Death caused by neglect?

Over a period of several months a 23-year-old bedridden woman suffered from increasing cachexia with numerous decubital ulcera in the parental house. The parents induced the hospitalization not before the patient reached the agonal phase. The reported case was especially spectacular because the left arm had fallen off and lay beside the woman showing maggot infestation, mummification and skeletonization. Against the parents a preliminary investigation for manslaughter by negligence was instituted. This case report describes the unusual course of disease and the striking familiar situation.     

Axe blow injuries caused by reflex action?

In cases of questionable insurance fraud through self mutilation axe blows now as before play an important role. Occasionally it is alleged that the billet began to totter during the stroke and that the left hand responded to this stimulus by an unwilled movement to the billet. By this the thumb or forefinger was placed unfortunately on the upper surface of the timber and hit by the chopper. According to the literature and on the basis of own experiments we estimate the reaction time, i.e. initiation time plus movement time, at 700 msec., at least, whereas the stroke needs only 220-290 msec. (chopper), and 280-380 msec. (axe), respectively, as could be shown in further experiments. That means, that the left hand can only touch the billet when the blow already has reached the goal. Hence unwilling finger mutilations can scarcely be the result of a "reflex action" of this kind.     

Animal bites caused by a song bird?

The report describes a case of post-mortem scavenging by a songbird. A married couple had opened the cage of an astrild (finch) prior to their joint death. The body of the wife showed unusual patchy epidermal lesions on parts of the body not covered by the clothing, which were obviously caused by the songbird. According to the observations made by Roll and Rous they are attributable to "pecking and pulling". The behaviour of the bird was most probably due to lack of fluid.     

DNA identification of skeletal remains by investigator’s intuition

In June 2006 a decapitated woman was found in a parking area of the motorway in the area of Prato (Florence). Since the body was beheaded and no victim’s documents or objects were present at the crime scene, identification at that time was impossible. However, DNA profile from woman’s bones were collected. In the same year (2003), a mother had reported her daughter's disappearance but the two events were not related at that time. About ten years later the mother’s DNA profile was finally acquired for a genetic identification of another girl’s body found in the Ferrara area. These genetic profiles were completely discordant. All these genetic comparisons were carried out on behalf of the prosecutors of the cities involved in the findings of the bodies and in the disappearance complaints, but due to the lack of a database the events remained disconnected. In January 2017, the head of the scientific police of Prato who had followed the investigation and questioned the mother of the missing girl found about ten years later, suggested to the magistrate to order the comparison of the mother's DNA with the genetic profile of the bones found in 2006. This comparison finally allowed the identification of the missing daughter.This story highlights the importance of having forensic DNA database to search for missing persons and how the investigator's intuition can play a key role in resolving criminal cases. In fact, databases of unknown bodies and relatives of missing persons were created in Italy as a part of national DNA database just at the beginning of 2018.     

Off-Label Prescribing by Psychiatrists: What is the Practitioner's Liability?

In psychiatry, the molecules available and the dosages recommended when a drug receives marketing authorization are not always adequate to treat patients with major behavioral disturbances. Off-label prescribing is frequent in this context, with regard to the indications and the dosages given as well as to the drug combinations used. However, if complications or death occur, the practitioner's liability may be engaged. The authors report three deaths attributed to off-label prescribing in psychiatry and which led to charges against the physicians. They review the precautions to be taken when prescribing in such conditions (no other possible treatment, existence of sound scientific evidence, consent obtained from the patient, or their legal representatives except in cases of force majeure) and the physician's liability if adverse events occur that could be attributed to off-label prescribing.     

Is the power of a state to impose sales tax in Nigeria fettered by the imposition of value added tax by the federal government?

The imposition of sales tax by some states in Nigeria has been resisted on the grounds either that a state lacks the power to impose taxes under Nigeria’s constitution or that a state cannot validly impose sales tax as long as the Value Added Tax Act, a federal law, remains in force, the Value Added Tax Act having ‘covered the field’. This article contends that none of these grounds is valid under Nigeria’s constitution: a state government can impose sales tax in exercise of its residual powers; and the doctrine of covering the field is inapplicable in the inquiry.     

Violence against women as conveyed by surveys – the Finnish case

The methodological choices made in a survey may partly shape the picture a survey conveys of partnership violence. This article considers some of the choices made in the Finnish survey on violence against women, such as the way the violence was defined and how the definition tried to take into account the special characteristics of this kind of violence, in order to help the respondents to identify and recall different events of it. The empirical analyses showed that the used definition of violence had not reached all the respondents representing different population groups. The experiences of partner violence among older, less educated women, and the experiences of those who felt embarrassed or ashamed to speak about issues concerning their partner or partnership, were more probably under-represented in the survey.     

Share repurchase regulations: Do firms play by the rules?

Open market share repurchases are strictly regulated to prevent managers from taking advantage of selling shareholders. We examine compliance with these rules in France, where the mandatory disclosure of share repurchases provides detailed information on repurchases actually undertaken. Using a database containing 36,848 repurchases made by 352 French firms over the period 2000–2002, we show that very few firms fully comply with the regulations for all their buybacks. We document that illegal repurchases before earnings announcements are the most detrimental to selling shareholders.     

Intimate Partner Violence and Child Adjustment: Moderation by Father Contact?

Little is currently known about father-child contact in families with histories of intimate partner violence (IPV), despite important implications of father contact for these families. The current study of 219 ethnically diverse children aged 6 to 12-years-old and their abused mothers examined relations between father contact, IPV, and children’s internalizing and externalizing problems. Approximately 30 % of the children had no current in-person contact with their father, while another 15 % saw their father every day of the past year. Child internalizing and externalizing problems were positively correlated with frequency of IPV, but unrelated to father contact. Controlling for marital status and mother education, father contact moderated relations between IPV and child externalizing, but not internalizing problems. While father contact was not associated with child adjustment across the entire sample, it did moderate relations between IPV and child behavior problems, suggesting that child contact with a less violent or nonviolent father or father figure might have a buffering effect on behavior problems in children exposed to IPV. Recommendations around father contact in families with IPV are discussed.     

An unusual death by transcranial stab wound: homicide or suicide?

Penetrating stab wounds of the brain are uncommonly seen in modern times and occur almost exclusively in homicides. We report an unusual death by self-stabbing. A 24-year-old man was found dead at home, the handle of a kitchen knife protruding from his forehead. Data such as the psychiatric history of the victim, the multiplicity and site of wounds, the implement used, the presence of hesitation, and defense wounds were studied to elucidate the manner of death, and the suicidal nature of the event was established after police investigation. Atypical injuries require a careful forensic investigation, and medico-legal aspects of the differentiation between homicide and suicide are discussed in this particular case. A review of the literature revealed few cases of suicidal transcranial stab wounds.     

Accidental autoerotic death by volatile substance abuse or nonsexually motivated accidents?

In contrast to typical autoerotic fatalities, when death is due to asphyxia mostly by mechanical compression of the neck, atypical autoerotic accidental deaths (AADs) involve sexual self-stimulation by other means such as electrocution or inhalation of chemical agents. Especially in lethal cases of volatile substance abuse (VSA), a differentiation between suicide or sexually or nonsexually motivated accident is often complicated in practical casework. Considering the small number of AADs involving chemical substance abuse reported in the literature, the number of unreported cases seems to be very high. We report about 5 lethal cases of VSA; analysis was performed using headspace solid-phase microextraction (HS-SPME) and gas chromatography-mass spectrometry (GC/MS). When headspace sampling is not performed at autopsy, the analysis of volatile substances can be very complicated. In 2 cases, an AAD was diagnosed considering findings at the scene, reconstruction of the event, and discussion of the circumstances of the death. These findings demonstrate the importance of VSA in atypical autoerotic asphyxia. Therefore, in cases of suspected lethal inhalational intoxications, as a matter of principle, headspace asservation should be performed at autopsy and an autoerotic motivational background should be taken into consideration for differential diagnosis.     

Homicide by asphyxia--yes or no? On the use of muscle histology

In two cases of death autopsy revealed large hemorrhages in the muscles of the neck, which lead to the conclusion of a murder by strangulation, e.g. with a soft tool. Histologic examination of the injured muscles didn't show any sign of vital reaction, which means, that they had developed post mortem. There was no reason for further suspicion of a violent crime. Later it became obvious, that neck lesions resulted from inadequate recovery and transport of the corpses. "Vital" type of muscular alteration is characterized by segmental or disk-like fragmentation of muscle fibres, loss of sarcoplasmatic cross-striation and appearance of pathologic longitudinal fibrillar structures. These signs are missing in case of a postmortal injury, whereas the cross striation is intact. The slides should be stained with PTAH. With these two cases we would like to demonstrate the importance of histologic examination of injured muscles, when question for intravital or postmortal injury rises.     

Rapid GC–MS confirmation of amphetamines in urine by extractive acylation

Amphetamine and related derivatives are widely abused central- and psychostimulants. Detection of certain derivatives, such as methcathinone, by commonly available immunoassay screening techniques is insufficient. Multi-analyte confirmations for amphetamine type stimulants are therefore required, but traditional gas chromatography–mass spectrometry methods necessitate lengthy analytical procedures with prolonged sample turn-around times. A validated rapid GC–MS assay for urinary confirmation of amphetamine, methamphetamine, methcathinone, ephedrine, norephedrine, methylenedioxyamphetamine, methylenedioxymethamphetamine, methylenedioxyethylamphetamine and N-methyl-1-(3,4 methylenedioxyphenyl)-2-butanamine is reported. The method entailed in situ derivatization of urine specimens by extractive acylation with pentafluoropropionic anhydride, followed by rapid chromatography on a microbore capillary column. Analytes were separated in less than 3 min and quantified simultaneously by selected-ion monitoring using stable isotope substituted internal standards. The total instrument cycle-time was 6 min per sample. The limits of detection were between 1.5 ng/mL and 6.25 ng/mL for the various analytes. Intermediate precision and accuracy were in the range of 6.3–13.8% and 90.5–107.3% for the respective analytes at the lower limit of quantitation, and between 5.8–12.6% and 95.4–103.1% for the high control. Long-term storage of methcathinone positive specimens at ?20 °C proved insufficient stability of this analyte. The proposed assay is precise and accurate for confirmation of amphetamine and derivatives in urine. The complementary approach of extractive-derivatization and fast GC–MS analysis is especially applicable in routine clinical settings where reduced sample turn-around times are required. Further investigation of cathinone as a possible metabolite of methcathinone is warranted, based on results from analyzed authentic urine samples.