Entrepreneurial ecosystems in cities: establishing the framework conditions

This study focuses on regional entrepreneurial ecosystems and offers a complex model of start-ups, Regional Entrepreneurship and Development Index (REDI) and six domains of the entrepreneurial ecosystem (culture, formal institutions, infrastructure and amenities, IT, Melting Pot and demand). Altogether they capture the contextual features of socioeconomic, institutional and information environment in cities. To explain variations in entrepreneurship in a cross-section of 70 European cities, we utilize exploratory factor analysis and structural equation modelling for regional systems of entrepreneurship using individual perception surveys by Eurostat and the REDI. This study supports policymakers and scholars in development of new policies conducive to regional systems of innovation and entrepreneurship and serves as a basis for future research on urban entrepreneurial ecosystems.     

Student and graduate entrepreneurship: ambidextrous universities create more nascent entrepreneurs

Despite its importance, student and graduate entrepreneurship at universities has received limited scholarly attention. The literature on university entrepreneurship has mainly focused on university scientists who have founded their own firms or spin-offs that were created based on intellectual property that is owned by universities. This paper focuses on technology new ventures that are created by university students and new graduates and aims to investigate the linkages among university-level organizational competencies, the entrepreneurial competencies of nascent entrepreneurs and the number of start-ups that have been created by students and new graduates. Our argument is that universities are heterogeneous in their resources and competencies, and these organizational competencies are influential on students in the development of entrepreneurial competencies and hence in the creation of start-ups. Differences among universities have led to information asymmetries and variances in entrepreneurial competencies among students and graduates. This study uses two data sources at the university level from Turkey. The first is the Technoenterprise Funding Support Program, and the second is the Entrepreneurial and Innovative University Index. Our research covers 40 universities over 3 years from 2012 to 2014, and we apply a panel data methodology. Our research suggests that (1) ambidextrous universities that provide a good context for the exploration and exploitation of new knowledge support their students in the development of entrepreneurial competencies and in starting their own technology new ventures, (2) the traditional role of universities (research and teaching) is important for the creation of entrepreneurial universities and finally, (3) university entrepreneurship is path-dependent.     

The role of universities in the location of innovative start-ups

Start-ups increasingly find the prospect of university–industry collaborations to be a powerful driver of innovation and entrepreneurship activity. Moreover, at the geographical level, they are attracted by teaching and research institutions, either public or private. This paper focuses on the role played by universities. Our hypothesis is that geographical proximity favors the transfer of knowledge and technology from universities to industries and, consequently, represents a positive factor for regional economic development. Results show that university spillovers are positively correlated with the creation of innovative start-ups. Furthermore, the presence of human capital (graduates) exerts a significant influence on the location decisions of start-ups, being a source for competitiveness for firms close to universities. Research quality, especially in the social sciences area, attracts innovative start-ups, while third-mission activities have a weak impact on locational choice.     

Public research and the innovation performance of new technology based firms

Assessing the role of publicly funded scientific research in entrepreneurial ecosystems is of great interest for science and entrepreneurship policy. Knowledge from academic research flows into the private sector through publications, patents, and researcher mobility as well as through direct interactions between founders and researchers at public research institutions (PRIs). New technology-based firms (NTBFs) are generally praised for high innovativeness despite their resource constraints and liability of newness. This study therefore investigates the impact of direct interactions with PRIs on NTBFs’ innovation success. In a large sample of NTBFs in Germany, we find that those firms engaging in such knowledge interactions are more likely to introduce new products and services to the market. The strength of this association, however, depends on interaction persistency, internal R&D and the founders’ academic backgrounds. Non-academic start-ups benefit more from continuous informal interactions if they pursue own R&D, which suggests that absorptive capacity matters. In academic start-ups, higher intensities of both formal and informal interactions are associated with greater innovation likelihood. Moreover, continuous informal interactions complement formal ones in the absence of own R&D activity.

     

Exploring the spatial heterogeneity of entrepreneurship in Chinese manufacturing industries

The prevalence of entrepreneurship not only varies across regions, but also differs among industries. Based on a unique data set of 146 manufacturing industries across 30 provincial-level regions in China, this study investigates the importance of geographical conditions and industry dynamism on net entry rates of Chinese manufacturing firms, and empirically explores how these two sets of factors jointly influence the distributional pattern of entrepreneurship. By testing for the significance of interactions between industry dynamism and local condition variables, it is found that growth-driven entrepreneurial activities favor agglomerated regions and do not value knowledge creation capability much, although both knowledge creation capability and factor market maturity are important for a region to attract entrepreneurs pursuing technological opportunities. For start-ups exploiting niche opportunities, agglomeration and local competition both act as deterring factors. Overall, the results confirm the importance of local conditions and industry structural variables as joint determinants of entrepreneurship in Chinese manufacturing industries.     

Labour as a knowledge carrier: how increased mobility influences entrepreneurship

According to the knowledge-based spillover theory of entrepreneurship (KSTE), entrepreneurship is positively associated with the knowledge endowment level. An increase in knowledge expands the opportunity set, which is then exploited by heterogeneous entrepreneurs. The objective of this paper is to empirically test the validity of the KSTE by employing a detailed database comprising more than 19 million observations for the period 2001–2008 at the level of individuals, firms and regions in Sweden. Knowledge is claimed to be partly embodied in labour, implying that an increase in labour mobility can be expected to influence knowledge endowment at the regional level. Our dependent variable is an individual who has remained in a region throughout the time period considered. Controlling for a number of other variables, inter-regional labour inflows and intra-regional mobility levels are shown to exert a strong positive effect on entrepreneurship. This contrasts with inter-regional outflows, which negatively affect entrepreneurial entry. Another noteworthy result is that the probability of exploiting an increased knowledge stock through entrepreneurship increases by 15 % points if the individual has previous experience in starting a firm.     

Determinant factors of university spin-off: the case of Korea

Increasingly more research has examined the creation of university spin-off firms as are seen as an important source of regional and national economic growth. However little is known about the factors influencing the formation of university spin-off in Asian countries, especially in Korea. This paper contributes to the literature on academic entrepreneurship by deepening our understanding on determinant factors of university spin-off in the case of Korea. We investigate organizational and institutional factors highlighted in the literature as influencing the creation of university spin-off companies. The Korean government has implemented the INNOPOLIS Research Institute Spin-off (IRIS) program to enable universities to create new firms within special research and development (R&D) zones to commercialize public R&D output. The capability of universities to establish new firms through the program varies; consequently, this study utilized 122 universities from 2013 to 2015 to analyze determinant factors that affect university spin-offs. Panel logit and negative binomial analysis results indicate that university location has the highest positive influence on IRIS. Government-sponsored funding has a negative impact; however, the likelihood that universities create spin-offs and the number of IRIS firms are positively and significantly affected by publications, patents, research funding, and number of university spin-offs.     

Closing the divide: accelerating technology commercialization by catalyzing the university entrepreneurial ecosystem with I-Corps™

In recent years, universities have seen an increasing amount of activity in entrepreneurship and commercialization, not only for students, but for faculty as well. Traditionally, these initiatives have been separate, such that programs and curriculum have been focused on supporting just students or just faculty. In 2012, the National Science Foundation (NSF) launched the NSF I-Corps? program, an innovative funding program that not only offered principle investigators (PIs) funding, but also exposed PIs to an innovation/entrepreneurship curriculum as well. The University of Michigan (U-M) was one of the first two NSF I-Corps? Nodes funded in 2012 and has leveraged the program to catalyze the entrepreneurial ecosystem. This paper describes the growth of this entrepreneurial ecosystem since 1983, the call of entrepreneurship in the U-M College of Engineering and describes the role the U-M NSF I-Corps? program has played across the university. The paper concludes with lessons learned and recommendations to administrators and policy makers considering more active promotion of academic entrepreneurship and commercialization in universities.     

Adverse selection and financing of innovation: is there a need for R&;D subsidies?

We study the interaction of private and public funding of innovative projects in the presence of adverse-selection based financing constraints. Government programs allocating direct subsidies are based on ex ante screening of the subsidy applications. This selection scheme may yield valuable information to market-based financiers. We find that under certain conditions, public R&D subsidies can reduce the financing constraints of technology-based entrepreneurial firms. First, the subsidy itself reduces the capital costs related to the innovation projects by reducing the amount of market-based capital required. Second, the observation that an entrepreneur has received a subsidy for an innovation project provides an informative signal to the market-based financiers. We also find that public screening works more efficiently if it is accompanied with subsidy allocation.     

Universities and the success of entrepreneurial ventures: evidence from the small business innovation research program

There has been little direct, systematic empirical analysis of the role that universities play in enhancing the success of entrepreneurial ventures. We attempt to fill this gap by analyzing data from the US SBIR program, a ??set-aside?? program that requires key federal agencies (e.g., Department of Defense) to allocate 2.5% of their research budget to small firms that attempt to commercialize new technologies. Based on estimation of Tobit and negative binomial regressions of the determinants of commercial success, we find that start-ups with closer ties to universities achieve higher levels of performance.     

From the entrepreneurial university to the university for the entrepreneurial society

This article examines how and why the role of the university in society has evolved over time. The paper argues that the forces shaping economic growth and performance have also influenced the corresponding role for the university. As the economy has evolved from being driven by physical capital to knowledge, and then again to being driven by entrepreneurship, the role of the university has also evolved over time. While the entrepreneurial university was a response to generate technology transfer and knowledge-based startups, the role of the university in the entrepreneurial society has broadened to focus on enhancing entrepreneurship capital and facilitating behavior to prosper in an entrepreneurial society.     

“To have and have not”: founders’ human capital and university start-up survival

In order to preserve innovation, knowledge development and diffusion, as well as the transfer of new technologies, the emergence of University Start-Ups (USU) and their survival as a particular dimension of performance represents a relevant research topic. As USU generally have scarce initial resources, the human capital of their founders is one of their main business assets. Although the survival of such firms is supposed to be heavily dependent on the human capital characteristics of their founders, this has not received enough attention in existing research. In this paper we investigate the contribution of founders’ specific human capital characteristics to the survival of USU, building on Gimeno et al. (Adm Sci Q 42:750–783, 1997) threshold model of entrepreneurial exit. We divide USU founders’ specific human capital into three components (entrepreneurship, industry and university) in order to better understand its impact on firm survival. Our theoretical model is empirically tested on a unique sample of Catalan USU through a logistic regression analysis. Coherently with our theoretical reasoning, the results show that industry human capital negatively affect USU survival, while university human capital and entrepreneurship human capital enhance the likelihood of USU survival.     

Parting the ivory curtain: understanding how universities support a diverse set of startups

Universities are widely recognized as a critical source of technological innovation and are heralded for the entrepreneurial ventures cultivated within their walls. To date, most research has focused on academic entrepreneurship—new ventures that spin out of academic laboratories. However, universities also give rise to startups that do not directly exploit knowledge generated within academic laboratories. Such firms—and the societal and economic benefits they create—are an important contribution of modern universities. We propose a framework for understanding the full scope of university entrepreneurship and its driving factors, with the goal of providing scholars, university administrators, and policymakers with insights regarding the resources required to foster entrepreneurship from within the ivory tower.     

The M&;A dynamics of European science-based entrepreneurial firms

This paper investigates the dynamics of a sample of 131 science-based entrepreneurial firms (SBEFs), selected out of 500 innovative small and medium enterprises (SMEs) that went public in Europe in the period 1995–2003. We found that the market for control of these firms was active, with most of our sample firms being acquired after their Initial Public Offering (IPO), usually by companies operating within the same industry. Floated SBEFs showed a higher propensity to be acquired than independent firms; this distinction persisted after controlling for intellectual capital and other possible determinants. While university affiliation enhanced attractiveness in the eyes of other companies, it negatively affected the propensity for acquisition. We argue that university-based firms do contribute to the technology transfer process, as evidenced by the widespread interest of the business world in investing in these firms. The creation of a SBEF is a first step in the process of commercial exploitation of university-research, while the subsequent step of going public is a sign of the success of this entrepreneurial venture. The take-over of SBEFs may be a final outcome of the process of knowledge diffusion.     

Country level efficiency and national systems of entrepreneurship: a data envelopment analysis approach

This paper tests the efficiency hypothesis of the knowledge spillover theory of entrepreneurship. Using a comprehensive database for 63 countries for 2012, we employ data envelopment analysis to directly test how countries capitalize on their available entrepreneurial resources. Results support the efficiency hypothesis of knowledge spillover entrepreneurship. We find that innovation-driven economies make a more efficient use of their resources, and that the accumulation of market potential by existing incumbent businesses explains country-level inefficiency. Regardless of the stage of development, knowledge formation is a response to market opportunities and a healthy national system of entrepreneurship is associated with knowledge spillovers that are a prerequisite for higher levels of efficiency. Public policies promoting economic growth should consider national systems of entrepreneurship as a critical priority, so that entrepreneurs can effectively allocate resources in the economy.     

Academic and Surrogate Entrepreneurs in University Spin-out Companies

Universities have two options when they formulate policies to develop new technology-based start-ups. One approach is to encourage faculty members to engage in this activity. Another avenue is to encourage surrogate (external) entrepreneurs to assume a leadership role. Based on a survey of technology transfer/business development officers at 57 U.K. universities, we examine perceptions regarding the advantages and disadvantages of each approach. We also analyze whether there are significant differences in these attitudes between universities that have launched many start-ups and those that have been less active in this arena. Our results imply that the most significant barriers to the adoption of entrepreneurial-friendly policies are cultural and informational. We also find that universities that generate the most start-ups have more favorable attitudes towards surrogate entrepreneurs. It appears that a combination of academic and surrogate entrepreneurship might be the best approach for universities that wish to develop successful technology-transfer based start-up companies.     

How and Why do Research-Based Start-Ups Differ at Founding? A Resource-Based Configurational Perspective

This paper studies the initial resources on which new organizations are based and how these resources interact with the institutional origin and market characteristics. Using a unique hand-collected data set of research-based start-ups (RBSUs), we empirically test how technological, financial and human resources relate to each other to form distinct starting resource configurations. We find four different start- ing configurations: “venture capital-backed start-ups,” “prospectors,” “product start-ups” and “transitional start-ups”. The results show that VC-backed start-ups are a minority while half of the firms start as prospectors. Market complexity and growth prospects influence the probability of starting with venture capital. The unclearness of the product market at founding characterizes prospectors, while product start-ups mostly have an almost market-ready product targeted at an international niche market. Transitional starters initially commercialize technical know-how through consulting and become product oriented later on. This discussion contributes to the debate concerning the interplay of environment and firm resources.     

Financing knowledge-intensive enterprises: evidence from CVCs in the US

Since the 1990s, the importance of corporate venture capital (CVC) programs has grown around the world. CVCs are investments that established firms make in entrepreneurial companies. At the most basic level, CVC describes an equity investment made by a corporation or its investment entity in a high growth, high potential, privately held business. There is no systematic evidence that corporate venture capital investments create value for the investing firms. Firm value, however, can be created as a result of other benefits from investing (e.g., accessing a new technology). These considerations can explain why many firms currently choose to operate venture units: They have recognized the importance of CVC for strategic innovation in addition to its potential to generate financial returns. Some evidence from the US context described in this paper supports this intuition.     

Do academic spinoffs internationalize?

Universities are key actors within the entrepreneurial ecosystems. A positive spillover of their knowledge creation and dissemination activity is the establishment of academic spinoffs. This study is one of the first to investigate the post-entry internationalization of academic spinoffs in terms of international sales. Adopting a conditional difference-in-differences approach, we matched a sample of 508 Italian academic spinoffs established between 1999 and 2014 with 404 comparable non-academic innovative start-ups. We find that university spinoffs are more prone to internationalize than their non-academic counterparts. This result is intrinsic to their affiliation with universities but is also related to the degree of internationalization of the parent university. A two-stage Heckman procedure confirms indeed that university internationalization translates into the internationalization of their spinoffs. This study contributes to different streams of literature, ranging from entrepreneurial ecosystems to academic entrepreneurship and internationalization literature due to the academic spinoffs’ nature of being a phenomenon at the confluence of several research fields.

     

Patent-based investment funds: from invention to innovation

In the context of entrepreneurial ecosystems the transformation of inventions to innovations is a crucial measure of success. Yet, the exploitation of inventions stemming from academic or corporate research is not as extensive as we would wish leaving room for improvements. Drawing on the knowledge spillover theory of entrepreneurship we investigate the phenomenon of patent-based investment funds as a new type of intermediary in the knowledge spillover process, which could facilitate the transformation from invention to innovation. Using a qualitative research design we analyze data from 21 expert interviews and complementary archival data. We find common characteristics of funds’ activities which decrease knowledge filters and fill the financing gap in the early stages of technology development. We propose a classification of commercialization strategies and link them to a specific set of invention characteristics. Our insights contribute to the knowledge spillover theory of entrepreneurship and to the knowledge filter model by providing empirical evidence for the division of labor between knowledge creator and commercialization agent. This adds to our view on entrepreneurial ecosystems as we shed light on different players in the transition process from invention to innovation and thus enhance our understanding of the multifaceted aspects in such an ecosystem. In addition, we refine the literature on patent-based investment funds by providing a classification of the entire commercialization spectrum used by funds and add to extant theorizing on how the nature of a technology determines its commercialization.