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The aim of this paper is to propose the main elements of a theoretical and methodological framework for the assessment of the success of complex policy mixes, to highlight the conflicts between individual instruments and other elements within those mixes and to propose policy recommendations in order to mitigate them. Some criteria are defined, and different levels of analysis are considered. The challenges in evaluating policy packages are illustrated with the case of the coexistence between renewable energy support and emissions trading schemes. It is shown that policy mixes inherently lead to interactions between the different instruments, either in the form of conflicts or synergies. Conflicts are horizontal (i.e., between different types of instruments) and/or vertical (i.e., between different administrative levels). It is suggested that mitigating those conflicts could require administrative coordination. Relevant coordination could take place between different administrative levels and relate to different instruments or different design elements within similar instruments. However, given the trade-offs between different criteria, the role of coordination is necessarily limited.  相似文献   
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Personality patterns, psychopathological symptomatology, dyadic relationship adjustment, and the characteristics of abuse suffered by a sample of women who attended residential services for battered women in Barcelona (Spain) are evaluated in this study. Over half the women had suffered psychological, physical, and sexual abuse on the part of her partner, mostly of long duration, and this had also been suffered by their children. The results obtained using the MCMI-II show a relatively low presence of anxious or depressive symptomatology and the predominance of a schizoid personality pattern. This means that clinical efforts need to be directed towards countering emotional withdrawal and social isolation. The importance of studying interpersonal patterns amongst battered women with a view to optimizing care and to preventing future victimization is also discussed.  相似文献   
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There have been many methods proposed to estimate the age of human bones in forensic medicine or in forensic anthropology, including those that assess histological structures. In this study, age was evaluated through the histomorphometric study of trabecular volume and cortical width of the right iliac crest. A total of 25 samples A total of 66 samples (42 male and 24 female) were obtained from necropsies of judicial cases, with ages ranging from 13 to 58years, who had died a sudden or violent death. The samples were obtained using Bordier's trocar for bone biopsy, in a period not exceeding 24h after death. The samples were examined without decalcification, with 96° alcohol dehydration, embedding in methyl methacrylate, and sectioned with a microtome Reichert (3μm). The sections were fixed on microscope slides and stained using toluidine blue, Goldner trichrome and hematoxylin-eosin methods. The samples were studied under a Leica DM LB microscope and the images were digitally captured. The digital images were processed using an image analysis program and data were analyzed using the SPSS statistical package. The results demonstrated that the combination of the trabecular volume and cortical width acted as predictors of the age in subjects which did not suffer from any deterioration of bone and/or mineral metabolism.  相似文献   
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The aim of this study was to assess the presence of alcohol, illicit drugs and medicinal drugs among Spanish drivers involved in fatal road accidents between 1991 and 2000. Samples were obtained for 5745 drivers killed in road accidents from January 1991 to December 2000. Of the samples, 91.7% represented males and 8.3% females; 40.7% were under 30 years of age, 31.9% were under 31-50 years of age, 19.5% were over 51 years of age, and for 7.9% the age was unknown. Between 1991 and 2000, some type of psychoactive substance was detected among 50.1% of those drivers killed in road accidents, this being mainly alcohol (43.8%) and, less frequently, illicit drugs (8.8%) and medicinal drugs (4.7%). In all the cases, in which alcohol was detected, combined use with other substances accounted for only 12.5%, whilst in the case of illicit and medicinal drugs, figures representing combined use with other substances were 75.6% for the former and 65.8% for the latter. For one in every three cases (32.0%), a blood alcohol level over 0.8 g/l was recorded; cocaine (5.2%), opiates (3.2%) and cannabis (2.2%) were the three illicit drugs most frequently detected. Among medicinal drugs, were benzodiazepines (3.4%), anti-depressant drugs (0.6%) and analgesics (0.4%). The results show the frequent presence of psychoactive substances, particularly alcohol, among Spanish motor vehicle users involved in fatal road accidents. It should be pointed out that illicit and medicinal drugs in combination with other substances were a common feature.  相似文献   
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Seminiferous tubules from heroin abusers and from rats chronically intoxicated by heroin samples presented a striking reduction in the thickness of the germinal epithelium. Light and electron microscopical studies showed a considerable increase of lipids and phagosomes in Sertoli cells, disorganization of their junction complexes, detachment of immature germ cells which appeared free in the tubular lumen, and formation of giant multinucleate spermatids. These alterations point out that Sertoli cells could be the target element for the toxic effect of heroin samples on the seminiferous epithelium.  相似文献   
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