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31.
Managing incidental findings in human subjects research: analysis and recommendations. 总被引:8,自引:8,他引:0
Susan M Wolf Frances P Lawrenz Charles A Nelson Jeffrey P Kahn Mildred K Cho Ellen Wright Clayton Joel G Fletcher Michael K Georgieff Dale Hammerschmidt Kathy Hudson Judy Illes Vivek Kapur Moira A Keane Barbara A Koenig Bonnie S Leroy Elizabeth G McFarland Jordan Paradise Lisa S Parker Sharon F Terry Brian Van Ness Benjamin S Wilfond 《The Journal of law, medicine & ethics》2008,36(2):219-48, 211
No consensus yet exists on how to handle incidental findings (IFs) in human subjects research. Yet empirical studies document IFs in a wide range of research studies, where IFs are findings beyond the aims of the study that are of potential health or reproductive importance to the individual research participant. This paper reports recommendations of a two-year project group funded by NIH to study how to manage IFs in genetic and genomic research, as well as imaging research. We conclude that researchers have an obligation to address the possibility of discovering IFs in their protocol and communications with the IRB, and in their consent forms and communications with research participants. Researchers should establish a pathway for handling IFs and communicate that to the IRB and research participants. We recommend a pathway and categorize IFs into those that must be disclosed to research participants, those that may be disclosed, and those that should not be disclosed. 相似文献
32.
Previous findings have shown both beneficial and adverse effects of parents’ attempts to influence adolescents’ eating habits.
The current study examined the differential effect of parents’ persuasion (e.g., encouragement, giving information) and pressure
tactics (e.g., guilt induction, ridicule) and the moderating influence of parental warmth on older adolescents’ emotional
and behavioral responses. An ethnically diverse sample of 336 older adolescents (M age = 18.6; SD = 1.1; 58.0% female) were surveyed. Adolescents who reported higher levels of pressure tactics by parents reported more negative
affect and behavioral resistance. Perceived parental warmth moderated the influence of persuasion tactics, but not pressure
tactics. For adolescents with low parental warmth, high levels of persuasion were associated with more negative emotional
and behavioral responses; persuasion had the opposite associations for adolescents with high parental warmth. These results
suggest that parental warmth plays an important role in how older adolescents respond to parents’ persuasion tactics. However,
when parents use more forceful pressure tactics to influence eating habits, adolescents react negatively regardless of the
overall quality of the parent–adolescent relationship. 相似文献
33.
Using data for the period 1989 – 2002, we examine the determinants of income inequality in post-communist economies. We find a strong positive association between equality and tax collection but note that this relationship is significantly stronger under authoritarian regimes than under democracies. We also discover that countries introducing sustainable democratic institutions early are characterised by lower inequality. We also confirm that education fosters equality and find that larger countries are prone to higher levels of inequality. 相似文献
34.
Courts resolving child support cases involving separated, divorced, and non‐marital children are charged with defining responsibility for health care coverage for the children under that order. This article explores historical and current medical child support requirements under Title IV‐D of the Social Security Act—the national child support enforcement (“IV‐D”) program. It analyzes legal requirements and policy recommendations, and provides a practical tool judges may use to determine whether health care coverage available to either or both parents is appropriate—that is, comprehensive, accessible, and affordable. 相似文献
35.
Ellen H. O’Donnell Melissa Moreau Esteban V. Cardemil Alisha Pollastri 《Journal of youth and adolescence》2010,39(1):12-22
Research on the mechanisms by which interparental conflict (IPC) affects child depression suggests that both parenting and
children’s conflict appraisals play important roles, but few studies have explored the role of general cognitive style or
included both parenting and cognitions in the same design. Moreover, the effects of IPC on minority children are not well
understood. In this longitudinal study, parenting was examined as a mediator of the relation between increasing IPC and change
in depression. General cognitive style was included as a moderator. The combined influence of parenting and cognitions was
also explored. A racially and ethnically diverse sample of 88 fifth and sixth graders from two urban schools reported their
cognitive style, depressive symptoms, and perceptions of conflict and parenting at two time points separated by one year.
Parental warmth/rejection mediated the relation between IPC and depression, and general cognitive style acted as a moderator.
Parenting, cognitive style, and IPC did not significantly interact to predict change in depression over time. Findings indicate
that both parenting and children’s general cognitive style play a role in understanding the impact of increasing IPC on children’s
well-being. 相似文献
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Ellen Sharp 《Citizenship Studies》2015,19(2):200-213
In this volatile moment in Latin America, when relations between the state and citizens are in flux, people at the margins of society draw on various notions of citizenship in social conflicts over proper behavior and the common good. I examine an intergenerational conflict over the legality of alcohol in an indigenous village in Guatemala to show how its protagonists creatively recombine different aspects of the various citizenship regimes that they have encountered. Elders have formed vigilante justice groups to combat the youth they consider gangsters. While the vigilantes draw upon a discourse of obligation to justify their actions, the generation below them counters with a language of rights. Some argue that citizenship is less meaningful in contexts where state power is ambiguous and extralegal violence is commonplace. I argue that in such contexts, it is not that citizenship does not have meaning, but rather that its meaning is intensely contested. 相似文献