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A rapid and efficient procedure is described for the extraction and analysis of oxazepam, the major urinary metabolite of diazepam in greyhounds. Urine was extracted by passing through a bonded silica column (Bond Elut) following enzyme hydrolysis. The adsorbed drug was eluted and then detected and measured by high performance liquid chromatography (HPLC). Recoveries were in excess of 85% at 50 ng/ml concentrations. Detection was possible up to 30 h after a single oral dose of diazepam (5 mg).  相似文献   
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Abstract: This is a case study of the campaign over daylight saving in New South Wales from the mid-1960s. The period leading to the legislation making daylight saving a permanent feature in 1972 was marked by the involvement of various groups, media campaigns and inter-governmental negotiations. After the legislation was passed, the character of the campaign changed. Conflict was confined mainly to the rural sector, where large-scale citizen involvement occurred. Many anti-daylight saving bodies were created and a petition of over 40,000 names protesting about daylight saving was presented to the Premier. The Country Party was pressured sufficiently to promise during 1973, 1974 and 1975 that a referendum would be held, and this was achieved in May 1976. The results of the poll showed majority approval lay with continuing daylight saving. Until 1972 the policy area appeared to correspond to Theodore Lowi's "regulative" category, but from 1972 the policy arena altered to one which may be viewed in terms of T. Alexander Smith's "emotive symbolic" policy. The article assesses the Smith concept and its usefulness in explaining the issue of daylight saving as an example of intense community debate.  相似文献   
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This article examines whether the payoff from engaging in innovation‐generating activities is contingent on an organization's level of customer and learning orientation. The authors suggest that innovative activity is associated with higher public service quality when the level of customer and learning orientation within the focal organization is high. They test this hypothesis by drawing on a novel panel data set covering all public nonspecialist hospital organizations in England. Using dynamic panel data estimation techniques, the authors find strong support for a direct relationship between innovative activity and public service quality and for a moderating role of both customer and learning orientation. These findings call for a contingency perspective on public sector innovation and highlight some of the boundary conditions that need to be in place if public service organizations are to benefit fully from their innovative activities.  相似文献   
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Presidential candidates regularly use crime issues to help win electoral support. Contrary to conventional wisdom, crime control became an issue in the 2008 presidential campaign. Despite decreasing crime rates and public opinion focused only temporarily on illegal immigration, the three major presidential candidates (Obama, Clinton, & McCain) discussed many anticrime initiatives during the campaign. Unlike past research which has found presidential candidates use primarily symbolic rhetoric in their anticrime rhetoric, all three presidential candidates in the 2008 presidential election were found to have employed tangible statements. The article discusses the different findings, making recommendations for future research.  相似文献   
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