Chlorinated Opium Alkaloid Derivatives Produced by the Use of Aqueous Sodium Hypochlorite During the Clandestine Manufacture of Heroin

Abstract:  A clandestine chemist was observed producing heroin from crude morphine utilizing a solution of sodium hypochlorite during the process. Numerous chlorinated opium alkaloid derivatives were created when the morphine acetylation reaction was quenched and neutralized with a solution of sodium hypochlorite and ammonium hydroxide. Four of these compounds, 1-chloroheroin, 1-chloroacetylcodeine, 1-chloro-O⁶-monoacetylmorphine, and 2'-chloropapaverine, were characterized via preparative isolation, gas chromatography/mass spectrometry, nuclear magnetic resonance spectroscopy, and independent synthesis. These chlorinated derivatives were formed via electrophilic aromatic substitution with free chlorine during the illicit process. Although no illicit heroin exhibits containing these compounds have been observed in seizures to date, mass spectral data are provided for several of these compounds for their identification should they be seen within future seizures of illicit heroin.     

Programs for Men who Perpetrate Domestic Violence: An Examination of the Issues Underlying the Effectiveness of Intervention Programs

This review paper seeks to explore some of the reasons why rehabilitation programs for male perpetrators of domestic violence appear to be less effective in reducing recidivism than programs for other offender groups. It is argued that while the model of systems response to domestic violence has predominated at the inter-agency level, further consideration might be given to way in which men’s intervention groups are both designed and delivered. It is concluded that the program logic of men’s domestic violence programs is rarely articulated leading to low levels of program integrity, and that one way to further improve program effectiveness is to incorporate some of the approaches evident in more general violence prevention programs and from what is know about good practice in general about offender rehabilitation.

Asian Male Domestic Violence Victims: Services Exclusive for Men

The main reasons abused men do not seek social services include their strong endorsement of social/cultural values and avoidance of gender role conflict. Through internet-based service connections, we did not find sources in Asia, Australia, or New Zealand that advertised programs exclusively for male victims of domestic violence (DV). Nine social services in Hong Kong and Singapore describe their work with men in DV situations, but the main focus is “men as perpetrators.” Targeting men as victims, 32 sources in Canada, the United States, and the United Kingdom describe services designed especially for male DV victims. Findings demonstrate that services for male victims must address such factors as secretiveness, cultural values, masculine identity, tolerance, shame, and loss of face.     

Between market forces and knowledge based motives: the governance of defence innovation in the UK

The purpose of this contribution is to examine the evolutionary transformations that have characterised the UK defence innovation system since the mid 1980s. It focuses on the central and challenging issue faced by the Ministry of Defence (MoD) in implementing effective governance mechanisms emerging from the continuous trade-off between short-term market driven measures motivated by efficiency arguments, and more long term and relational considerations in terms of knowledge economics. Furthermore, in terms of technology transfer, this evolution has been accompanied by a gradual shift from an initial logic of spin-off to society expected from government driven military projects, to a logic of spin-in where the main concern of the military sector is to broaden its industrial and R&D base.

The National Partnership for Environmental Priorities Program

The National Partnership for Environmental Priorities (NPEP) program was created by the U.S. Environmental Protection Agency (USEPA) to reduce or eliminate the nation's production of hazardous wastes and products. The NPEP is a voluntary program that provides incentives to public, private, and federal organizations that minimize their use and generation of thirty-one priority chemicals. These chemicals are considered to be persistent, bioaccumulative, and toxic in the environment and present health risks to human and ecological receptors. The USEPA estimates that 90 percent of priority chemicals are used or produced during manufacturing of various household and industrial products and, as a result, end up in municipal and industrial waste streams. Ultimately, these chemicals find their way back into the environment through wastewater discharges, incineration, or other disposal practices. The NPEP program supports the goals of the National Waste Minimalization Program by encouraging simple waste minimalization solutions such as recycling, replacement, or elimination of wastes or products that contain priority chemicals, and cradle-to-cradle management of waste. Although the USEPA does not limit waste minimalization practices to only the priority chemicals, the program has set specific goals to track the elimination of these thirty-one chemicals to the environment on an annual basis.     

Multiple Symmetric Lipomatosis

A significant number of medicolegal deaths involve ethanol. Deaths may be related to the acute, intoxicating effects of ethanol, either in decedents or within persons responsible for causing the deaths of others. Additionally, deaths may be related to chronic alcoholism. A chronic alcoholic may display characteristic external features which allow an observer, such as a forensic pathologist or other physician, to conclude that he/she is probably an alcoholic. Herein, the authors report two decedents with a rare condition known as “multiple symmetric lipomatosis” (MSL), which has a strong correlation with chronic alcoholism. Identification of the peculiar features associated with MSL should prompt the forensic pathologist to consider chronic alcoholism as a probable diagnosis.     

Relation of Antisocial and Psychopathic Traits to Suicide-related Behavior Among Offenders

Offenders with antisocial traits are relatively likely to attempt suicide, largely because they are more likely to have high negative emotionality and low constraint. Among 682 male offenders, we tested whether negative emotionality, low constraint, and also substance use problems mediated any relationship between antisocial personality disorder (ASPD) and psychopathy on the one hand, and suicide-related behavior (SRB) and ideation on the other. ASPD and the impulsivity/lifestyle features of psychopathy weakly predicted SRB. High negative emotionality and low constraint (but not substance use) mediated the relation between ASPD and SRB. Impulsivity/lifestyle features of psychopathy retained an independent predictive effect. Self-report psychopathy measures added unique predictive variance to the Psychopathy Checklist—Revised. We discuss implications for suicide risk assessment and prevention.

Thatcherism and the Conservative Party

Neither spatial models of party competition nor the 'Westminster' model of British politics explain the phenomenon of Thatcherism. One explanation of its success, examined by Crewe and Searing, suggests that Mrs Thatcher sought to convert the Conservative party and the wider electorate to her distinctive brand of liberal Whiggism and traditional Toryism. They found little evidence of the success of this, however, among the British electorate as a whole. In this paper, data from the first national survey of Conservative party members demonstrates that she had little success in converting the Conservative party to these ideas either, although she did have a secure ideological base within the party. The results also suggest that her successor, John Major, has a rather different support base within the party from that of Mrs Thatcher. The implications of these findings for spatial models of party competition and the Westminster model of British politics are discussed.     

Mass Political Behaviour: Is There More to Learn?

Research progress in voting studies and party competition, the mass media, work on social movements, interest groups and collective action, is reviewed for the last decade. Theoretical impetus in applied work seems weak in British studies; sub-fields of research are being pursued in isolation. In electoral studies at least there are signs of over-specialization and loss of valuable interconnections with the mainstream of political science. A number of pathways for improving the state of the art are identified, focusing on a renewal of theoretical input, the correction of some 'system biases', greater methodological pluralism and more integration of demand-side and supply-side studies.     

Emergency relief programmes for pastoral communities

This article makes the case that emergency relief programmes in pastoral areas of Africa do little to relieve the fundamental effect of famine, which is destitution. It argues that traditional mechanisms of coping with drought are often disrupted by food-aid programmes, especially Food-For-Work. Three case studies from Sudan and Kenya are used to support the argument. The article concludes by making policy recommendations for emergency programmes to be more effective in meeting the primary need of pastoralists following severe drought, which is to rebuild herds and therefore their livelihoods.