Brain Fluid Content Related to Body Position and Postmortem Interval – An Animal Model

Adult male Sprague Dawley rats were euthanized and placed in a horizontal or vertical (head‐down) position at room temperature, after which brain fluid content was measured by a moisture analysis technique at variable time points. No significant difference in brain fluid content was observed between horizontal and vertical postmortem positions. A significant increase in brain fluid content was demonstrated 3, 6, and 24 h after death, with maximal fluid content observed at 24 h. Specifically, the brain fluid content of control animals was 77.79 ± 0.36%, increasing to 80.05 ± 0.22% at 24 h (p < 0.0001). This study has demonstrated no significant differences in brain fluid content related to postmortem position, suggesting that a head‐down position is not associated with increased brain fluid content or swelling. However, significant temporal increases in brain fluid content after death, most likely related to cerebral liquefaction, occur.     

Counterfeit Adderall Containing Aceclofenac from Internet Pharmacies

A nontargeted approach based on liquid chromatography equipped with a quadrupole time‐of‐flight mass detector (LC‐MS Q‐TOF) joined to nuclear magnetic resonance (NMR) analysis allowed rapid identification and quantification of the anti‐inflammatory drug aceclofenac in illegal Adderall tablets. The largest chromatographic peak had m/z = 354.030 and m/z = 376.012 matching, respectively, the ionic structures (M + H)⁺ and (M + Na)⁺ of a molecule M. The accurate mass data generated the molecular formula C₁₆H₁₃Cl₂NO₄. A screening of the pharmaceutical active substances having that molecular formula together with the MS/MS fragmentation pattern suggested aceclofenac. Aceclofenac structure was unambiguously confirmed by ¹H and ¹³C NMR experiments. The aceclofenac content was 90 mg/tablet (RSD 2%) as detected by quantitative NMR. Information on the identity and content of illegal drugs is required for legal purposes; it supports in evaluating the effective impact on users safety, and it is useful for control laboratories using a targeted approach in their analytical activities.     

Partner Violence Entrapment Scale: Development and Psychometric Testing

This article describes the development and testing of the psychometric properties of the Partner Violence Entrapment Scale (PVES), an instrument that evaluates the women’s perceived reasons for staying in violent partner relationships. After initial pilot testing, the scale was administered to 213 Spanish women who were victims of intimate partner violence (IPV). An exploratory factor analysis identified six factors: Socio-Economic Problems, Attachment and Fear of Loneliness, Blaming Oneself and Resignation, Impact on Children, Fear of Harm and Worry for the Partner, and Feelings of Confusion. Discriminant validity was established by demonstrating associations between PVES factors and socio-demographic, clinical and abuse variables. The scale appears to be a useful assessment tool for social and clinical settings. Its factor structure, reliability, and validity need to be replicated in other populations and samples.     

University–Industry collaboration in the biopharmaceuticals: the Italian case

We investigate the determinants of University–Industry (U–I) interactions in the biopharmaceuticals in Italy over the period 2004–2010, choosing co-publishing as a proxy of U–I partnerships. We construct a novel dataset of co-published articles, that contains measures of proximities, agglomeration, firms’ and universities’ characteristics. Following a consolidated methodology, we integrate our dataset of effective interactions with the set of all potential interactions, to estimate probabilistic models for the occurrence and the intensity of U–I interactions. Our main findings confirm and extend the predictions of the previous literature: (1) geographical proximity and prior partnership increase the probability and the intensity of co-publication; (2) the proximity of a firm to other biopharmaceutical firms and universities attenuates the relevance of geographical proximity; (3) there exists complementarity between prior partnerships and geographical proximity. A novel result is that firms’ and Universities’ size, firms’ R&D and patents expenditure and the composition of the academic staff as well as quality of academic research exert a significant impact on the intensity of co-publishing.     

In need of a cultural shift to promote restorative justice in Southern Europe

The article describes the main results of a European project on restorative justice (RJ) called Freedom Wings (FW) and presents a new model to promote RJ in Southern Europe, which was developed from FW findings. The principal mission of the FW project is to disseminate best practices of RJ within a transnational network and to promote community participation in conflict prevention and resolution, in order to support individual and social well-being. This paper presents the main findings of multiagency and professional focus groups exploring restorative approaches and community justice. Observation of experts’ social representation of RJ helped the authors to understand the operation of the justice systems in each country and the attitudes of senior officials towards implementing restorative practices in a way that actively involves the community. The analysis shows the necessity of a cultural change in order to switch from a form of RJ managed by the judicial system to one led by the community. The EU project enabled the research team to theorize a model for promoting a relational and restorative community.     

Do Market Participants Learn? The Case of the Budapest Stock Exchange

In the paper we consider one of the faster growing Central European emerging markets: the Budapest Stock Exchange (BSE), in order to see whether the market becomes more weak-form efficient over time. The Hungarian exchange is selected because it is the oldest stock exchange operating in the region and, in 1995, it was the first Central European exchange admitted by the London Stock Exchange as a properly regulated stock exchange. As an econometric tool for comparative analysis, we use a Test for Evolving Efficiency (TEE). In a comparison of nine stocks and the market index (BUX) we found that the BSE becomes more mature but the process is surprisingly slow.     

Diagnose: Doppelbefund — Ursache: ungeklärt? Die kontroversen um den „demokratischen Frieden“

Ohne Zusammenfassung     

“Success” in policy piloting: Process,programs, and politics

Research has demonstrated that pilots contain multiple shifting purposes, not all of which relate to simple policy testing or refinement. Judging the success of policy pilots is therefore complex, requiring more than a simple judgment against declared goals. Marsh and McConnell provide a framework against which policy success can be judged, distinguishing program success from process and political success. We adapt Boven's modification of this framework and apply it to policy pilots, arguing that pilot process, outcomes and longer-term effects can all be judged in both program and political terms. We test this new framework in a pilot program in the English National Health Service, the Vanguard program, showing how consideration of these different aspects of success sheds light on the program and its aftermath. We consider the implications of the framework for the comprehensive and multifaceted evaluation of policy pilots.     

中俄有名合同立法比较研究

在市场经济条件下,民事主体之间的关系主要体现为合同关系。从计划经济向市场经济转型的中俄两国对各种类型的合同作出了立法规定,但由于两国改革设计者在改革思路、立法理念、国情和立法技术上的不同,两国对有名合同的规定仍然存在着重大的差别。中国至今没有完成民法典的制定,一部统一的单行合同法对各种类型的合同作出了系统规定。虽然中国合同法秉承世界先进理念,立法技术也臻于成熟,但典型合同的类型仍显不足,且受市场经济不够完善的制约,法律条文留给民商事主体的创新空间非常有限,从而影响有名合同的民间生成。俄罗斯民法典规定的有名合同类型相对较多,较之中国合同法的规定也相对完备,值得中国借鉴,但在理论与立法技术上亦存在诸多问题,亦有吸收中国立法经验的必要。     

Politicians Using History

The political potency of national history has been understood for generations. Yet there has been an unquestionable surge in history's political influence over the last twenty or thirty years, as the various history wars that have broken out around the world attest. Australia has been no exception: disputes over its national story continue to generate considerable controversy in the media, in politics and in public debate. But how has this politicisation of the past affected Australian political history in the present? This paper examines how history is practised in contemporary Australian politics — and notices an increasingly strategic use of the past by politicians in recent years.