异位方配合甲氨蝶呤治疗异位妊娠32例临床观察

目的:观察自拟异位方配合甲氨蝶呤(MTX)治疗异位妊娠的临床疗效.方法:采用随机方法将63例异位妊娠患者分为两组(治疗组32例,对照组31例),治疗组接受异位方加MTX治疗,对照组单用异位方治疗,观察两组保守治疗异位妊娠疗效.结果:治疗组治愈率(84.37%)高于对照组(64.51%)(P<0.05);治疗组β-HCG下降至正常及阴道流血停止时间短于对照组(P<0.01或P<0.05);治疗组治疗后包块缩小程度大于对照组,差异有显著性(P<0.01).结论:中西医结合治疗异位妊娠可加速β-HCG下降,减少阴道流血时间,促进包块吸收,降低保守治疗风险,缩短疗程,提高疗效,有利于输卵管功能的恢复.     

管制刑执行中存在的问题及对策探讨

管制刑是我国所独创的一种刑罚 ,在历史上曾经发挥了不可替代的重要作用 ,但今天 ,管制刑的执行面临诸多问题 ,难于实现刑罚的特殊预防与一般预防功能。因此 ,必须对管制刑作出必要的改革 ,完善立法 ,改革执行机构和执行方式 ,以适应时代和社会发展之要求 ,确保管制刑刑罚目的的实现。     

LANGUAGE AND CULTURE IN CHILD LAW

In 1989, England and Wales adopted the Children Act, a revolutionary and pioneering statute changing the language of the law in regards to the needs of children. Judge Nigel Fricker, the family court judge in York, formerly in Sheffield, describes this change and some of its effects on the practice of judging, the law, and the behavioral sciences regarding children.     

论金代社会治安管理制度

十二世纪初，骁勇的女真民族以武立国后，对社会治安的管理逐渐系统化，确立了社会治安秩序管理、市场经济秩序治安管理、户籍管理、交通安全管理、消防管理等专项治安管理制度，为维护政权的稳定和社会的发展起到强大的推动作用，在中国古代治安史上具有十分鲜明时代和民族特色，对今天的社会治安管理也具有一定的借鉴意义。     

An improved method for semen alpha-L-fucosidase typing--distribution in the Wuhan population of China

An improved method for the separation of the genetic variants of alpha-L-fucosidase in human semen is described. The method involves, isoelectric focusing in ultrathin-layer PAG containing a mixture of ampholines, pH 5-7 and pH 3.5-9.5, and separator HEPES. The Fu pattern obtained is simple, easy to interpret, and reproducible. The occurrence of fucosidase phenotypes in 189 semen samples from the population of Wuhan was investigated, and the frequencies of the Fu alleles were calculated.     

A rapid method for the extraction of cocaine and benzoylecgonine from body fluids

A method has been developed for the rapid extraction of cocaine and benzoylecgonine from post-mortem blood and urine samples. Solid phase columns containing C8 packing material gave clean, emulsion free extracts from body fluids. The total time for each extraction was approx. 10 min and the system has the capacity for the simultaneous extraction of up to 10 samples. Urine can be extracted directly, blood samples were sonicated before extraction to allow for their easy passage through the columns. The method gave excellent recoveries of cocaine (98-100%) from spiked samples at concentrations of between 50 ng/ml and 10 micrograms/ml. Analysis of the extracts was by high performance liquid chromatography (HPLC).     

Extravasation of plasma proteins in brain trauma

The cellular distribution of extravasated plasma proteins in cortical contusions was studied with an immunoperoxidase method using polyclonal antibodies against human plasma albumin, alpha 1-acid glycoprotein, alpha 2-macroglobulin, alpha 1-antitrypsin, transferrin, hemopexin, haptoglobin, fibrinogen, fibronectin and immunoglobulin G. The material consisted of 24 human autopsy brains with a primary diagnosis of cerebral contusion due to blunt trauma. The time interval between injury and death ranged between minutes and 7 years. Immediately after the trauma, a complete breakdown of the blood-brain barrier (BBB) occurred with hemorrhage and extravasation of all types of plasma proteins. This was followed by spreading of edema fluid within the extracellular space in and around the wound. Uptake of extravasated protein by glial cells began on the 3rd day followed by proliferation of reactive astrocytes whose ample cytoplasm appeared to serve as a reservior for the extravasated plasma proteins. Within the reactive astrocytes, plasma proteins and S-100 protein had a similar and diffuse distribution in the immunostained sections. The plasma proteins once incorporated into the glial cells remained unchanged for several years with little sign of degradation. It is suggested that the extravasated plasma proteins subsequent to uptake and processing by the glial cells, may serve some important physiological function in wound healing.     

Melatonin concentrations in the sudden infant death syndrome

To examine a possible relationship between pineal function and the sudden infant death syndrome (SIDS), samples of whole blood, ventricular cerebrospinal fluid (CSF) and/or vitreous humor (VH) were obtained at autopsy from 68 infants (45 male, 23 female) whose deaths were attributed to either SIDS (n = 32, 0.5-5.0 months of age; mean +/- S.E.M., 2.6 +/- 0.2 months) or other causes (non-SIDS, n = 36, 0.3-8.0 months of age 4.3 +/- 0.3 months). The melatonin concentrations were measured by radioimmunoassay. A significant correlation was observed for melatonin levels in different body fluids from the same individual. After adjusting for age differences, CSF melatonin levels were significantly lower among the SIDS infants (91 +/- 29 pmol/l; n = 32) than among those dying of other causes (180 +/- 27; n = 35, P less than 0.05). A similar, but non-significant trend was also noted in blood (97 +/- 23, n = 30 vs. 144 +/- 22 pmol/l, n = 33) and vitreous humor (68 +/- 21, n = 10 vs. 81 +/- 17 pmol/l, n = 15). These differences do not appear to be explainable in terms of the interval between death and autopsy, gender, premortem infection or therapeutic measures instituted prior to death. Diminished melatonin production may be characteristic of SIDS and could represent an impairment in the maturation of physiologic circadian organization.