Statistical analysis of DNA mixtures using peak area information and allelic drop out

A case of a woman killed in Perugia is reported. The woman was beaten to death and the body showed evidence of bites, kicks and punches. The request of the Court was to verify the presence of bites and if they belonged to humans. Morphological examination and genetic analysis with human Y-specific markers were performed in order to verify the origin of the bites. The DNA profile from the surrounded area of the traces was compared with the profile of the victim's husband (the suspect).The results showed a match between the profile of the suspect and that of the traces for all loci examined. Due to the fact that also other relatives of the husband's male lineage lived in the same house, it was not possible to identify the man who really contributed to the traces. Therefore, the analysis was implemented with autosomal STR markers, which showed a mixed genetic profile. In order to verify the number and the identity of the contributors, statistical analysis based upon peak area information was performed with Probabilistic Expert Systems.     

Unpacking Acculturation: Cultural Orientations and Educational Attainment Among Mexican-Origin Youth

Given educational risks facing Mexican-origin children of immigrant parents, it is important to understand how aspects of the acculturation process influence Mexican-origin youth's educational success. Drawing from selective assimilation theory, this study examined how cultural orientations across myriad facets of acculturation were associated with the educational attainment of second-generation Mexican immigrant youth. The sample included 755 Mexican-origin youth (50% female) in the "Children of Immigrants Longitudinal Study." Results from structural equation models indicated that youth reporting greater facility in the English language and a stronger value on familism attained higher levels of education in young adulthood than did other youth. Parents' U.S. social ties and youth's value on early paid work were associated with less educational attainment. Innovative findings from this study indicate the importance of considering both Mexican and American cultural orientations across myriad facets of acculturation for understanding second-generation immigrant Mexican youth's educational attainment.     

A contractual model of the voting behavior of the supreme court: The role of the chief justice

Political scientists have long debated the role of the Supreme Court in public policymaking. Much of the debate has centered around the issue of judicial independence from political factors. Despite a rather extensive debate in the literature, the question of independence has rarely been subjected to systematic testing. This paper examines the role of the Chief Justice of the Supreme Court in linking decisions of the Court to the desires of Congress. Specifically, the paper focuses on the role of the Supreme Court Chief Justice as an agent of Congress that reacts to budgetary signals sent by the Congress. The resulting relationship between budgets allocated to the Court and decisions reached by the Court are analyzed from 1946 to 1988.     

Profiling tax and financial behaviour with big data under the GDPR

Big data and machine learning algorithms have paved the way towards the bulk accumulation of tax and financial data which are exploited to either provide novel financial services to consumers or to augment authorities with automated conformance checks. In this regard, the international and EU policies toward collecting and exchanging a large amount of personal tax and financial data to facilitate innovation and to promote transparency in the financial and tax domain have been increased substantially over the last years. However, this vast collection and utilization of “big” tax and financial data raise also considerations around privacy and data protection, especially when these data are fed to clever algorithms to build detailed personal profiles or to take automated decisions which may exceptionally affect people's lives. Ultimately, these practices of profiling tax and financial behaviour provide fertile ground for discriminating processing of individuals and groups.In light of the above, this paper aims to shed light on the following four interdependent and highly disputed areas: firstly, to review the most well-known profiling and automated decision risks emerged from big data technology and machine learning algorithmic processing as well as to analyse their impact on the tax and financial privacy rights through their immense profiling practices; secondly, to document the current EU initiatives toward financial and tax transparency, namely the AEOI, PSD2, MiFID2, and data retention policies, along with their implications for personal data protection when used for profiling and automated decision purposes; thirdly, to highlight the way forward for mitigating the risks of profiling and automated decision in the big data era and to investigate the protection of individuals against these practices in the light of the new technical and legal frameworks; in this respect, we finally delve into the regulatory EU efforts towards fairer and accountable profiling and automated decision processes, and in particular we examine the extent to which the GDPR provisions establishes a protection regime for individuals against advanced profiling techniques, enabling thus accountability and transparency.     

Validation of a large Italian Database of 15 STR loci

Results from a collaborative exercise with proficiency testing conducted by 20 Italian laboratories on the 15 loci included in the Identifiler kit were analyzed by allele sharing methods and by standard population genetics tests. The validated database, including about 1500 subjects, was merged with that of a previous exercise conducted on nine loci, and the resulting allele frequencies, subdivided by Italian region, were published on-line.     

Giant Diaphragmatic Lipoma: Two Autopsy Case Reports and Review of the Literature

Lipomas are common benign tumors most frequently found within the subcutaneous areas of the body. Deep-seated lipomas are rare and tend to be larger than cutaneous ones. Lipomas are rarely seen in the thoracic cavity, and they are usually located in the mediastinum, bronchiole, and lungs. Diaphragmatic lipomas have been occasionally reported in the literature, the first being described by Clark et al. in 1886. The authors report two rare cases of giant diaphragmatic lipoma incidentally found during forensic autopsies. In the first case, a Caucasian 85-year-old woman burned to death with another passenger, after her methane-fueled car collided with another car on a highway near Terni, Umbria, Italy. In the second case, a Caucasian 45-year-old man collapsed while walking through the countryside of Perugia. In either case, a large mass in the thorax was observed. The definitive pathologic diagnosis was giant intrathoracic diaphragmatic lipoma without evidence of malignancy. The authors also review the relevant literature and discuss differential diagnoses. These case reports contribute to the establishment of the actual incidence of diaphragmatic lipomas.     

Regulatory harmonization and agricultural biotechnology in Argentina and China: Critical assessment of state‐centered and decentered approaches

The international harmonization of technology‐related regulations seeks certain norms across diverse contexts. Harmonization efforts are based primarily on the promulgation of state‐centered command and control forms of regulation, though they may also be accompanied by the diffusion of more plural approaches that are decentered from the state. We contrast the ways in which the “proper” use of transgenic cotton seed technologies is understood in harmonizing regulations with the way this technology is used in practice in regions of Argentina and China. We find divergence that poses challenges for both state‐centered and decentered approaches to harmonization. While state‐centered approaches are blind to some critical processes on the ground, decentered strategies are found wanting in situations where norms remain deeply contested amongst actors situated in very uneven power relations. In both cases, we find that establishing and securing norms that are socially just and environmentally sustainable means attending much more explicitly to the political economies in which technological practices actually take root.     

Migrant women breadwinners in Italy during the crisis: improvement or trap?

Gender gaps in some aspects of the labour market in Europe narrowed during the recent economic crisis, mainly because men were hit harder and because of the ‘added worker effect’. Therefore, the number of families with a single wage-earner, in particular female-headed households, increased. However, the differential impact of the crisis on male and female labour force in part was an unintended effect of the ‘gendered’ and ‘racialized’ structure of the labour market. Occupational concentration in care and reproductive work and the public sector in fact protected women from unemployment. Adopting an intersectional approach and using individual and household data from the Labour Force Survey from 2008 to 2015, the aim of this paper is to assess to what extent the gendered and ‘racialized’ structure of the Italian labour market has changed, both from a quantitative and qualitative point of view, and to what extent the increase in female breadwinner families, especially among migrants, hides widening or narrowing intersectional inequalities by gender and citizenship.