Prevalence and correlates of psychopathic traits in the household population of Great Britain

There are no previous surveys of psychopathy and psychopathic traits in representative general population samples using standardized instruments. This study aimed to measure prevalence and correlates of psychopathic traits, based on a two-phase survey using the Psychopathy Checklist: Screening Version (PCL: SV) in 638 individuals, 16–74 years, in households in England, Wales and Scotland. The weighted prevalence of psychopathy was 0.6% (95% CI: 0.2–1.6) at a cut score of 13, similar to the noncriminal/nonpsychiatric sample described in the manual of the PCL: SV. Psychopathy scores correlated with: younger age, male gender; suicide attempts, violent behavior, imprisonment and homelessness; drug dependence; histrionic, borderline and adult antisocial personality disorders; panic and obsessive–compulsive disorders. This survey demonstrated that, as measured by the PCL: SV, psychopathy is rare, affecting less than 1% of the household population, although it is prevalent among prisoners, homeless persons, and psychiatric admissions. There is a half-normal distribution of psychopathic traits in the general population, with the majority having no traits, a significant proportion with non-zero values, and a severe subgroup of persons with multiple associated social and behavioral problems. This distribution has implications for research into the etiology of psychopathy and its implications for society.     

“‘I have done it and I have got to die’: Coroners' inquests of abortion deaths in Rhode Island, 1876–1938.”

This article offers an analysis of abortion deaths among white working-class women in Providence County based on thirty-three coroners records from 1876 to 1938. Most women were single and in their twenties: they chose abortion either because their lover was married, or they were too ashamed of their premarital sexual activity to confront their parents. Married women, on the other hand, did so primarily due to economic factors, extramarital affairs, or a strong desire for no more children. In seeking abortions, single women depended on lovers while married women relied on sisters or sisters-in-law. In investigating the deaths resulting from these abortions, coroners called husbands, but not lovers, before the inquests and sought out antemortem statements. Yet only 39% of cases had dying declarations: either doctors refused to participate in interrogating women on their death beds, or women refused to identify abortionists. Of the abortion providers identified, 45% were physicians. Working-class status did not prevent these women, and later their families, from securing expensive medical care from doctors. Both inquests and newspaper coverage in Providence County differ from studies by other scholars who find these venues used as mechanisms to embarrass women and warn single women of urban threats, and to target midwives over physicians. The evidence points to analogous handling of doctors and laypeople, and of married and single women. No intimate details of women's lives were exposed and newspapers did not use sensationalized headlines to draw attention to the illegal activity of abortion. Coroner inquests asked questions necessary to investigate death from a criminal activity, not to take a moral stance on female sexuality.     

Access and allocation in global biodiversity governance: a review

International Environmental Agreements: Politics, Law and Economics - Access and allocation is one of the five analytical themes of the science plan of the Earth System Governance (ESG) project....     

'Deeds and Words': The Woman's Press and the Politics of Print

The political and constitutional impact of the early twentieth-century British women's suffrage movement has been the subject of extensive research since the advent of second-wave feminism, yet the broader cultural impact of the movement remains a developing scholarly area. Murray examines the role of the Woman's Press, the publishing house established in 1907 as a strategic component of the Pankhursts' influential Women's Social and Political Union. The press is located within multiple and interpenetrative analytical contexts: examined in turn are its role in the various power struggles of the WSPU and the broader British suffrage movement; its significance as an independent means of cultural production around the contested site of the suffragette; and its ambiguity as a feminist publishing house run by male pro-suffragist and lobbyist, Frederick Pethick Lawrence. The Woman's Press and its central London retail outlet figured prominently in WSPU administration as a material concern-as literature packing department, revenue raiser and recruiting centre. Yet, symbolically, the Woman's Press was also integral to the campaigning of the WSPU to an extent that has generally remained under-examined. As an independent publishing house the press constituted a vital conduit guaranteeing the entry of suffrage arguments into public discourse, and a crucial tool for appropriating and refashioning the contested image of the suffragette in the wider politico-cultural landscape of the day. Acknowledging the significance of the Woman's Press provides both a necessary historical context for the post-1970 feminist press boom, as well as a counterpoint to the ongoing political-financial conundrums that beset its modern descendents.     

Framing a Needed Discourse on Health Disparities and Social Inequities: Drawing Lessons from a Pandemic

COVID-19 provides numerous opportunities for policy makers to consider matters of social equity in relation to the field of public health. Specifically, by reflecting on health disparities in relation to the disproportionate impact of COVID-19 on minority and historically underserved populations, we can leverage a needed discourse on health outcomes for many communities. Grounded in the social determinants of health conceptual framework, this essay explores the application of the disproportionate impact of COVID-19 to vulnerable populations and communities of color for a discussion of strategies for minimizing health disparities.     

Churches,mosques, and condoms: understanding successful HIV and AIDS interventions by faith-based organisations

There are an estimated 33 million people living with the Human Immunodeficiency Virus (HIV) worldwide. While national education campaigns have been successful in providing a broad platform of awareness of HIV and AIDS, within some countries faith-based organisations (FBOs) have assumed an important role in educating and supporting local communities to reduce HIV transmission. This article conceptualises the successful characteristics of a Christian organisation in West Papua and a Muslim organisation in Thailand. The ability of both these FBOs to engage successfully with their communities on issues of sexual practice provides important lessons for other FBOs seeking to reduce HIV transmission.     

Sarcomeric gene mutations in sudden infant death syndrome (SIDS)

In developed countries, sudden infant death syndrome (SIDS) represents the most prevalent cause of death in children between 1 month and 1 year of age. SIDS is a diagnosis of exclusion, a negative autopsy which requires the absence of structural organ disease. Although investigators have confirmed that a significant percentage of SIDS cases are actually channelopathies, no data have been made available as to whether other sudden cardiac death-associated diseases, such as hypertrophic cardiomyopathy (HCM), could be responsible for some cases of SIDS. The presence of a genetic mutation in the sarcomeric protein usually affects the force of contraction of the myocyte, whose weakness is compensated with progressive hypertrophy and disarray. However, it is unclear whether in the most incipient forms, that is, first years of life, the lack of these phenotypes still confers a risk of arrhythmogenesis. The main goal of the present study is to wonder whether genetic defects in the sarcomeric proteins, previously associated with HCM, could be responsible for SIDS. We have analysed 286 SIDS cases for the most common genes implicated in HCM in adults. A total of 680 mutations localised in 16 genes were analysed by semi-automated matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry (MALDITOF-MS) using the Sequenom MassARRAY(?) System. Ten subjects with completely normal hearts showed mutated alleles at nine of the genetic variants analysed, and one additional novel mutation was detected by conventional sequencing. Therefore, a genetic mutation associated with HCM may cause sudden cardiac death in the absence of an identifiable phenotype.     

Validation of a method to detect cocaine and its metabolites in nails by gas chromatography-mass spectrometry

The objective of the present work was to compare previously published methods and provide validation data to detect simultaneously cocaine (COC), benzoylecgonine (BE) and norcocaine (NCOC) in nail. Finger and toenail samples (5mg) were cut in very small pieces and submitted to an initial procedure for external decontamination. Methanol (3 ml) was used to release analytes from the matrix. A cleanup step was performed simultaneously by solid-phase extraction (SPE) and the residue was derivatized with pentafluoropropionic anhydride/pentafluoropropanol (PFPA/PFP). Gas chromatography-mass spectrometry (GC-MS) was used to detect the analytes in selected ion monitoring mode (SIM). Confidence parameters of validation of the method were: recovery, intra- and inter-assay precision, as well as limit of detection (LOD) of the analytes. The limits of detection were: 3.5 ng/mg for NCOC and 3.0 ng/mg for COC and BE. Good intra-assay precision was observed for all detected substances (coefficient of variation (CV)<11%). The inter-assay precision for norcocaine and benzoylecgonine were <4%. For intra- and inter-assay precision deuterated internal standards were used. Toenail and fingernail samples from eight declared cocaine users were submitted to the validated method.