Iatrogenically-related, fatal methotrexate intoxication: a series of four cases

Since the early eighties, the folic antagonist methotrexate (MTX) has been used in long-term treatment of rheumatoid arthritis. Because of the high toxic potential clinical and laboratory controls at regular intervals and patient education in order to avoid misadventure is of overriding importance. We present four cases of fatal MTX intoxication due to medical malpractice from the Tübingen Institute of Forensic Medicine autopsy material, which show the severe consequences of MTX overdose. It becomes evident that among non-rheumatologists there still is need for information about toxicity and dose limitation in MTX low-dose treatment.     

刑事司法与人权保障——欧中刑事司法改革比较与借鉴

本文剖析了欧陆各国刑事司法改革的主要成果以及欧洲人权法院在人权保障方面发挥的重要作用,并对欧中刑事司法制度予以比较。     

Horizontalföderalismus und Schweizer Demokratie

Der Beitrag analysiert den zunehmenden Horizontalföderalismus im politischen Mehrebenensystem der Schweiz und fragt nach den Gefahren und Chancen für die Weiterentwicklung der Schweizer Demokratie. Die Evaluierung erfolgt auf der Basis der komplexen Demokratietheorie von Fritz Scharpf, ergänzt um die konstitutiven Perspektiven einer reflexiven Demokratietheorie. Insgesamt wird deutlich, dass der Horizontalföderalismus vor allem aus einer liberalen Position innerhalb einer Output‐ orientierten Demokratietheorie als problematisch angesehen werden muss, da die kantonale Exekutive gegenüber der Legislative gestärkt wird. Der Aufsatz betont aber die Chancen für die schweizerische Demokratie, da der Horizontalföderalismus grosse Ähnlichkeiten mit den Entscheidungsfindungsprozessen auf internationaler Ebene besitzt. Er liefert damit der Schweiz ein Übungsfeld, um ihr traditionell sehr introvertiertes Verständnis von demokratischer Selbstbestimmung zu überwinden und anzuerkennen, dass in einer interdependenten und mobilen Welt die “Einbeziehung des (externen) Anderen” ein Bestandteil einer legitimen demokratischen Ordnung darstellt.     

The Case for Congressional Budgeting

William Howard Taft and Frederick A. Cleveland’s vision of executive budgeting clashes with the unique status of the U.S. Congress among the world’s legislatures, and its proponents may exaggerate the potential for presidents to act as fiscal guardians. This article advocates more congressional budgeting by reinstituting effective fiscal rules and strengthening the role of the budget committees. These mechanisms would enhance fiscal discipline and aid consolidation.     

Dual citizenship and theories of democracy

Dual/multiple citizenship has become a widespread phenomenon in many parts of the world. This acceptance or tolerance of overlapping memberships in political communities represents an important element in the ongoing readjustment of the relationship between citizens and political communities in democratic systems. This article has two goals and parts. First, it evaluates dual citizenship from the perspective of five normative theories of democracy. Liberal and republican as well as multicultural and deliberative understandings of democracy deliver a broad spectrum of arguments in favour of dual citizenship. Only communitarians fear that dual citizenship endangers national democracies. Nevertheless, empirical evidence and national policies largely contradict these fears. The second part of the article reverses the perspective and shows that most theories of democracy do not only legitimate and facilitate the acceptance of dual citizenship – the phenomenon of multiple citizenships induces innovation in democratic theory in turn. A second look at the relationship between dual citizenship and theories of democracy reveals that dual citizenship stimulates refinements, expansions and reconceptualisations of these theories for a transnationalising world.     

Writing Human Rights History—And Social Science Encounters

This review essay on Aryeh Neier's The International Human Rights Movement: A History (Princeton University Press, 2012) discusses Neier's central themes: the origins and maturation of the movement and its effects, including the expansion of human rights and humanitarian law, enhanced criminal accountability for human rights crimes, and the appearance of criminal tribunals, culminating in the International Criminal Court. An overview is interspersed by imaginary conversations between Neier and scholars who speak to his themes, especially legal scholar Jenny Martinez, political scientists Margaret Keck and Kathryn Sikkink, historians Devin Pendas and Tomaz Jardim, and sociologists John Hagan, Daniel Levy, Natan Sznaider, Joachim Savelsberg, and Ryan D. King. Linking a practitioner's account with scholarly analyses yields some benefits of “Pasteur's Quadrant.”     

Countering Hybrid Eco-threats to Global Security Under International Law: The Need for an Comprehensive Legal Approach

Threats to environmental security (‘eco-threats’) face not only shortcomings of environmental protection during hostilities under the Law of Armed Conflict. Considering the new ‘Hybrid Threat’ concept, which had recently been discussed by NATO, the authors recognise from the perspective of International Law the need for adopting a comprehensive legal approach towards such threats. The International Environmental Law, the International Humanitarian Law and the Customary International Law show some shortcomings to tackle the new challenge. In the focus is the rule of law, in particular the principle of proportionality, which can play a role when countering such threats and legal rules can have a positive effect on the international community’s ability to act.     

The Impact of Drinking Water Quality and Sanitation on Child Health: Evidence from Rural Ethiopia

This paper examines the association between stored drinking water quality and sanitation on diarrhoea incidence among under-five children in Ethiopia. Using primary household survey data and microbiological water quality testing for Escherichia coli, our results show that uncontaminated stored drinking water and safe child stool disposal are associated with decreased child diarrhoea incidences of 18 and 20 percentage points, respectively. In contrast, neighbourhood concentration of pit latrine shows an increased incidence of child diarrhoea of 16 percentage points. To protect rural children from the risk of contracting diarrhoea, improving household drinking water quality and changing people’s behaviour towards safe sanitation practices is needed.