Evaluation and applicability of Alere iCup DX 14 for rapid postmortem urine drug screening at autopsy

Performing point‐of‐care urine drug screen testing at autopsy by a forensic pathologist may provide an early indication of the presence of analytes of interest during autopsy. An evaluation for the screening of 14 classes of common drugs of abuse in postmortem urine by the point‐of‐care screening device, Alere iCup DX 14, is presented. One hundred ninety postmortem urine samples were screened with the iCup occurring at autopsy by the forensic pathologist. Positive and negative results obtained from the screening kit were evaluated against confirmatory test results obtained using routine forensic toxicology analyses that employed LC‐MS/MS and GC‐MS to detect a combination of over 85 common drugs of abuse and medications. Sensitivity for each respective iCup drug class ranged from 66% (buprenorphine) to 100% (methadone, tricyclic antidepressants). Specificity for each respective iCup drug class ranged from 89% (benzodiazepines) to 100% (amphetamines, barbiturates, buprenorphine, 3,4‐methylenedioxymethamphetamine, methadone). Positive predictive values ranged from 44% (benzodiazepines) to 100% (amphetamines, barbiturates, buprenorphine, methylenedioxymethamphetamine, methadone), while negative predictive values ranged from 96% (methamphetamine) to 100% (barbiturates, methadone, tricyclic antidepressants). A high false‐positive rate was yielded by the benzodiazepine class. The lack of fentanyl screening in the point‐of‐care device is a significant limitation considering its prolific prevalence in forensic casework. The results obtained in the study should be acknowledged when considering the use of the Alere iCup DX 14 in the context of postmortem casework to help indicate potential drug use contemporaneously with autopsy and when requiring such preliminary results prior to the release of a final forensic toxicology report.     

Intimacy at work: servant and employer relations in Que horas ela volta? (The second mother)

ABSTRACT

This chapter examines servant/employer relationships in Anna Muylaert’s film Que horas ela volta? (The Second Mother, 2015). Written in the first person by someone who locates herself as a white, middle-class Brazilian from humble origins who has lived abroad for nearly 30 years, the chapter focuses on the sense of discomfort caused on her by the film and by Brazilian middle-class reliance on domestic servants, whilst at the same time analysing the role played by intimacy and servitude in the film. In dialogue with Sérgio Buarque de Holanda’s definition(s) of “cordialidade” (and with later discussions of it), the chapter examines what “cordialidade” can mean in the context of employers/domestic servants relationships in contemporary Brazil.     

A comparative analysis of regionalism in the Global South: The security and defence dimension of Unasur and the African Union

The aim of this article is to compare Unasur and the African Union with regard to their institutional structure, agenda and performance. Although some scholars have made comparative assessments of regional institutions in the same region or comparisons between regional projects worldwide and the European Union, there are still few academic contributions which develop a cross-regional comparison among regional initiatives from different regions of the Global South. By assessing the cases of Unasur and the African Union, and particularly Unasur’s Defence Council and the AU’s Peace and Security Council, taking into account their institutional structure, performance and limitations, and the role of regional leaders and exogenous actors in both cases, we have elaborated an analytical framework aiming to identify and explain the similarities and differences between two regional institutions outside Europe. Based on the contributions of comparative regionalism and the evaluation of Unasur and the AU, we conduct a comparative analysis of both regional organisations, giving specific attention to their security and defence agendas, moving forward the empirical and analytical agenda of comparative regionalism.     

Does Welfare Provision Promote Democratic State Legitimacy? Evidence from Brazil's Bolsa Família Program

Conditional cash transfer programs may boost the electoral fortunes of incumbents among beneficiary groups, but do they also influence recipient attitudes toward state legitimacy? This article examines the relationship between Brazil's Bolsa Família program and recipients’ sense of the Brazilian state's political legitimacy, from 2007 to 2014. Using AmericasBarometer data and propensity score matching, this study provides evidence that targeted cash benefits correlate with citizens’ views of the state, but that this relationship is limited to increasing trust in core state institutions, local government, and incumbent political actors. Diffuse dimensions of regime legitimacy, including recipients’ sense of political community, support for regime principles, and retrospective perceptions of national economic performance, are largely unaffected by the receipt of targeted benefits. Over time, the evidence also suggests that the impact of program receipt on these measures of support remains largely unchanged.     

Memory and ethnic leadership among Afro-descendants and Africans in Argentina

Several academic studies on African and Afro-descendant population in Argentina have made reference to the ‘oblivion’ of the black component in the creation of an ethnically white and homogeneous national collective. The present work intends to rethink this issue in light of an Anthropology of the memory that promotes a critical analysis of the construction of an African past as diacritic of ethnic identification and interaction strategy related to the largest society, paying special attention to the actions of ethnic leaderships in the Afro community. In other words, we consider the processes of creation and validation of a social memory from an African origin by the ethnic entrepreneurs. For that purpose, we conduct a qualitative study employing the techniques characteristic of anthropological ethnography.     

Forensic Pathological Considerations of a Unique Case of “Complicated Suicide”*,†

In the forensic literature, peculiar and uncommon cases of suicides defined as “complicated” are reported. In these circumstances, the suicide method chosen by the victim fails, and death occurs due to a subsequent unforeseen accidental event defined as secondary trauma. Through retrospective examination of 25,512 autopsies in 27 years (1993–2019) at the Bureau of Legal Medicine of Milan, a unique case of complicated suicide was identified from a total of 4497 suicides. It concerns an elderly man who, after killing his wife by inflicting incised wounds to her neck, tried to hang himself by tying a rope to a heater and jumping from the window located over the heater itself. However, the rope suddenly snapped and the man fells to the ground causing fatal traumatic injuries. Death occurred because of an accidental event caused by the failure of the hanging mechanism. Therefore, a peculiar yet characteristic case of complicated suicide is described.     

Why Foundations Flourish: A Comparative Policy Framework to Understand Policy Support for Foundations across Countries*

Abstract

Philanthropic foundations have bloomed since the 1990s, contributing to the expansion of third sectors worldwide. This research aims to contribute to the comparative analysis of the policy conditions that shape the development – size and structure – of foundation fields across countries. A framework for comparative policy analysis encompassing key dimensions of policy support – policy milestones, levers, and alternatives – is proposed and applied to five southwestern European countries. Results demonstrate that although Spain, France, Italy, Belgium, and Portugal have been traditionally clustered under the same corporatist foundation model, their foundation fields vary widely in terms of size, structure and institutional embeddedness.