Protecting cultural heritage in war zones

In the throes of war, protecting such cultural heritage as the Bamiyan Buddhas, the Mostar Bridge, the Timbuktu libraries and Palmyra supposedly is a priority on the international public policy agenda; but government responses so far have been limited to deploring such destruction. This article explores the evolving, albeit contested, norm of the ‘responsibility to protect’ (R2P) and its relevance for cultural heritage. There is no need for a hierarchy of protection – civilians or culture – because the juxtaposition is as erroneous as choosing between people and the environment. This essay begins with a discussion of cultural heritage and defines the scope for the application of any new international normative consensus. It then explores why R2P, in the original concept of the International Commission on Intervention and State Sovereignty (ICISS), is an appropriate framework for thinking about cultural protection, despite considerable political headwinds. It then examines the current opportune political moment and existing legal tools. Finally, there is a brief consideration of the obstacles facing the creation of a better framework for cultural protection in zones of armed conflict.     

UDHR and Modern Slavery: Exploring the Challenges of Fulfilling the Universal Promise to End Slavery in All Its Forms

This article reflects on the prohibition of slavery set out in article 4 of the 1948 Universal Declaration of Human Rights, and analyses efforts undertaken in the years since to fulfil this commitment. It first addresses the evolution in the prohibition from historic forms of slavery to contemporary forms of slavery and human trafficking. Second, the article examines the Modern Slavery Act 2015 and the National Referral Mechanism to appreciate the UK's efforts to implement various international commitments to prohibit slavery, noting that the current focus towards criminalisation and the meagre support offered as victim protection does not constitute a sufficiently comprehensive strategy towards effective prohibition. Third, areas for reform are identified that could reorient government strategy toward more effective victim protection and support, starting with better identification of victims. And finally, the article argues in favour of actions that seek to prevent modern slavery crimes and abuse, including with a more robust regulatory framework that engages private sector actors to recognise the risks of slavery and exclude forced labour from supply chains.     

现代化背景下黔西北苗族民俗体育研究

苗族是我国古老的少数民族之一,它在漫长的不断迁徙历史发展中创造了自己独具特色的民族传统体育。黔西北(贵州省毕节地区)是我国苗族主要聚集地之一,民俗体育类型多样,形式丰富。但在现代化背景下也面临着历史传承的紧迫问题。     

合成毒品4-甲基甲卡西酮的危害及滥用的预防

4-甲基甲卡西酮是苯丙氨的衍生物质,是基于卡西酮的人工合成兴奋剂。本文对4-甲基甲卡西酮的起源和管制情况进行介绍,并进一步研究了其对人体的危害、依赖性及毒性。分析了我国预防4-甲基甲卡西酮滥用存在的问题,有针对性地提出解决对策。     

Interaction of 3,4-methylenedioxymethamphetamine and methamphetamine during metabolism by in vitro human metabolic enzymes and in rats

Illicit amphetamine-type stimulant (ATS) tablets commonly contain one or more active ingredients, which have hallucinogenic and/or stimulant effects. Because components such as 3,4-methylenedioxymethamphetamine (MDMA) and methamphetamine (MA) in ATS tablets have similar chemical structures, they could be metabolized by common metabolic enzymes. To investigate potential metabolic interactions of ATS tablet components, we studied the in vitro metabolism of MDMA and MA using human metabolic enzymes. MDMA and MA were mainly metabolized by cytochrome P450 2D6 (CYP2D6) and mutually inhibited the production of their main metabolites. In vivo experiments were also performed using intravenous administration of MDMA, MA, or their mixture to rats. The plasma concentrations of MDMA and MA after co-administration were higher than those after administration of MDMA or MA alone. The results in this study imply that multiple components in ATS tablets can interact to mutually inhibit their metabolism and potentially enhance the toxicity of each component.     

Comparison of bulk and compound-specific δ13C isotope ratio analyses for the discrimination between cannabis samples

Five marijuana samples were compared using bulk isotope analysis compound-specific isotope ratio analysis of the extracted cannabinoids. Owing to the age of our cannabis samples, four of the five samples were compared using the isotope ratios of cannabinol (CBN), a stable degradation product of Δ(9)-tetrahydrocannabinol (THC). Bulk δ(13)C isotope analysis discriminated between all five samples at the 95% confidence level. Compound-specific δ(13)C isotope analysis could not distinguish between one pair of the five samples at the 95% confidence level. All the measured cannabinoids showed significant depletion in (13)C relative to bulk isotope values; the isotope ratios for THC, CBN, and cannabidiol were on average 1.6‰, 1.7‰, and 2.2‰ more negative than the bulk values, respectively. A more detailed investigation needs to be conducted to assess the degree fractionation between the different cannabinoids, especially after aging.     

Does Hyperthyroidism Increase Risk of Death Due to the Ingestion of Ecstasy?

Ecstasy (3,4-methylenedioxymethamphetamine, MDMA) is a psychoactive amphetamine derivative widely used for recreational purposes. Deaths caused by acute drug intoxication with MDMA are rare but can often involve a severe hyperthermic episode. The factors underlying the increased risk of some ecstasy users to a fatal drug reaction are not known. We present a case report of a 24-year-old woman who developed fatal hyperthermia with multi-organ complications following MDMA use and was found at autopsy to have diffuse thyroid hyperplasia (Graves' disease). An antemortem blood MDMA concentration of 0.68 mg/L was measured in a sample obtained on admission to hospital. Although a cause and effect cannot be established, as the thyroid hormone is a major regulator of thermogenesis, we suggest that hyperthyroidism predisposed the subject to ecstasy-induced hyperthermia and that a pre-existing defect affecting temperature status could be one factor in explaining some ecstasy intoxication deaths.     

Validation of LAB color mode as a nondestructive method to differentiate black ballpoint pen inks

Nondestructive digital processing methods such as lab color mode (available in Adobe Photoshop) are emerging as alternative methods for forensic document examiners to use when attempting to differentiate writing instrument inks. Although these techniques appear to be viable, little data currently exists regarding the known or potential error rates associated with these techniques. Without adequate data, the validity and reliability of these techniques, including lab color, can not be established. In an attempt to begin to address these issues, 44 black ballpoint ink pens were obtained and used to create 990 pen-pair samples for analysis using established lab color mode techniques. No erroneous findings of "different" were reported following the examination of the known pen-pair combinations in which the same pen was used to create the samples (n = 44). Of the remaining 946 samples, 737 pen-pair samples were differentiated using the lab color mode method, while 209 samples were unable to be differentiated and were recorded as either being "similar" (n = 153) or "unsure" (n = 56). Comparison of the lab color mode results with the results obtained through additional testing using traditional infrared reflectance and infrared luminescence test methods showed that lab color differentiated 102 pen-pair samples (11%; 102/946) that were not differentiated using a VSC-4C.     

Dynamischer Erhaltungsbegriff und Verbesserungspflicht des Vermieters im MRG

Im Bereich voller Anwendbarkeit des MRG hat der Vermieter für eine Erhaltung des Mietgegenstandes "im jeweils ortsüblichen Standard" zu sorgen. Der vorliegende Beitrag versucht, dem unbestimmten Gesetzesbegriff der Ortsüblichkeit anhand der bisherigen Rechtsprechung Konturen zu verleihen sowie Kriterien für die bisher unklare Abgrenzung zwischen dem dynamischen Erhaltungsbegriff des § 3 MRG und der Verbesserung nach § 4 MRG herauszuarbeiten.