Hair analysis of opiates in mothers and newborns for evaluating opiate exposure during pregnancy

The increasing interest in toxicological hair analysis as a marker of human exposure to xenobiotics such as illicit substances or therapeutic drugs, has been made feasible by the extension of mass spectrometry, a highly sensitive method of detection. A newborn exposed to drugs in utero can suffer from a varying degree of withdrawal syndrome, a few days after birth. If of opiate origin, the withdrawal syndrome can be treated with morphine, among other therapeutics, but it is not easy to diagnose because of atypical symptoms presented by neonates and especially when maternal drug addiction has not been revealed. To assess and measure toxicological factors linked with the appearance and the severity of this syndrome, maternal and neonatal matrices such as urine, meconium and hair were collected during a protocol approved by the ethical committee. Opiates in particular were measured with GC-MS and potential combined dependences (cannabis, cocaine, amphetamine, LSD and benzodiazepines) and/or substitutive therapeutics (methadone or buprenorphine) were also assessed in 17 mother/neonate couples. Gestational opiate exposure profiles were drawn up and linked with the observed withdrawal syndromes. A withdrawal syndrome seems to appear more frequently after foetal exposure to an association of opiates/substitutive molecules (8 out of 10 withdrawal syndromes observed in this study), although the impact of cocaine and benzodiazepines must also be taken into account. The results obtained in neonatal hair make it possible to affirm foetal drug exposure and are in accordance, for the majority, with the appearance of a neonatal withdrawal syndrome (NWS). Neonatal hair analysis could contribute to assess in utero exposure to opiates, particularly when results in urine and meconium are negative or when these matrices are not available.     

A comparison of animal jaws and bite mark patterns

The purpose of this study was to compare the jaw shapes and bite mark patterns of wild and domestic animals to assist investigators in their analysis of animal bite marks. The analyses were made on 12 species in the Order Carnivora housed in the Mammalian Collection at the Field Museum of Natural History in Chicago, Illinois. In addition to metric analysis, one skull from each species was photographed as a representative sample with an ABFO No. 2 scale in place. Bite patterns of the maxillary and mandibular dentition were documented using foamed polystyrene exemplars, which were also photographed. A total of 486 specimens were examined to analyze the jaw and bite mark patterns. A modified technique for measuring intercanine distances was developed to more accurately reflect the characteristics seen in animal bite marks. In it, three separate areas were measured on the canines, rather than just the cusp tip. This was to maximize the amount of information acquired from each skull, specifically to accommodate variances in the depth of bite injuries.     

Psychosocial Aspects of Body Mass and Body Image Among Rural American Indian Adolescents

This study examines the psychosocial risks associated with body weight (BMI) and body image in a southeastern, rural Lumbee American Indian community. A total of 134 adolescents (57% female) were surveyed over 2 years at ages of 13 and 15 years. On average, boys (55%) were more likely to be overweight or obese than were girls (31%). BMI was related to a variety of weight control efforts including onset and frequency of smoking, dieting, and body dissatisfaction. Body dissatisfaction was associated with peer relations, self-esteem, anxiety, depression, and somatization in adolescence. Longitudinally, psychological health, peer competence, and ethnic identity were associated with positive body image. In boys, early ethnic identification was associated with the development of later body image. Implications of findings for ethnic- and gender-specific interventions are discussed.On faculty at Tulane University. Received PhD in clinical and developmental psychology from the University of Minnesota. Major research interests are developmental psychopathology and personality, and diverse topics in American Indian mental health.Department of Psychology, University of Florida, Gainesville, Florida. A graduate student in the developmental psychology. Received BS in psychology from Tulane University in 2004. Major research interests include developmental psychopathology, emotion regulation, and biological responses to stress.Department of Psychology, Tulane University, New Orleans, Louisiana. A doctoral student in developmental and school psychology at Tulane University. Received MS in psychology from Tulane University and BA in psychology from CUNY Hunter College. Major research interests are social and personality development, developmental psychopathology, minority mental health, and the impact of hearing loss on social and cognitive development.     

Financing multifamily rental housing: The changing role of lenders and investors

Abstract

A broad consensus exists that there are significant barriers to accessing capital markets for multifamily rental housing, particularly for housing targeted at low‐and moderate‐income households. While there is a growing secondary market for multifamily mortgages, the market is in the early stages of development and remains quite small. Expanding this market requires increasing standardization of mortgages, increasing credit quality with better underwriting and credit enhancement, and educating investors as to the risks and returns of multifamily investments. In addition, dramatically improved data collection on the performance of multifamily investments and analysis on the determinants of success are needed.     

Partner Violence in Women's Prison: The Social Consequences of Girlfriend Fights

In this article, we use qualitative interviews with female inmates to examine how these women describe the consequences of girlfriend fights in prison. We find that they describe these fights as both social and pervasive. We also find that those who were counseled by staff members describe being empowered by the event. We argue that prison officials must use better methods of identifying and addressing partner violence in prison. We also recommend the use of widespread programs aimed at reducing partner violence.     

Temperance Culture and the Repression of Scientific Inquiry Into Illegal Drug‐Altered States of Consciousness

American scientific inquiry into the understandings of drug‐altered states of consciousness is underdeveloped primarily because government regulations embedded within a temperance culture has repressed it. Despite preliminary evidence of the therapeutic value of altered states of consciousness associated with the use of illegal drugs to both physical and mental health, science has been able to do little to understand this potential. Within this essay, we examine the influence of this temperance culture on government regulations and its impingement on scientific practice in the study of illegal drug‐altered states of consciousness as the explanation for much of the failure of science to adequately explore these lines of inquiry. Much of our analysis is based upon examples from research in the area of alcohol studies, as the temperance movement arose primarily in response to this particular drug.     

Encryption and the first amendment

Recently, only secret government agencies were concerned about cryptography. It now is an important matter for many individuals and businesses who use the Internet. That has led to an intense effort on the part of several governmental agencies to control cryptography. This article provides an explanation of the evolution of cryptography, a synopsis of the evolving cryptography debate, an examination of the different interests represented within the debate and a framework for analyzing the First Amendment issues that are involved. The paper applies the framework to the Clinton administration's initiatives and finds them unconstitutional.