努力提高领导干部有效应对媒体的能力

通过新闻媒体来引导舆论、凝聚人心、服务工作,是各级党政组织特别是各级领导干部重要而又紧迫的任务。     

Tianjin Surges Forward in the New Millennium

The history of Tianjin Municipality dates back to Emperor Yongle's reign in the early Ming Dynasty (1368-1644). In 1860, Tianjin was designated as anopen port city, one the first in China to trade with foreign countries. It furtherdeveloped into one of the modern industrial bases of north China, due to itsposition as the communications hub of the Haihe River and its close proximityto Beijing, the capital of China. Since China's, opening, the city has turned anew page in its history of in…     

Simultaneous analysis of d-3-methoxy-17-methylmorphinan and l-3-methoxy-17-methylmorphinan by high pressure liquid chromatography equipped with PDA

d-3-Methoxy-17-methylmorphinan (Dextromethorphan, DXM), which is a structural analog of morphine and codeine, has been widely used as a non-narcotic antitussive agent. It is a safe drug in therapeutic dose and does not produce analgesic effects, while its enantiomer, l-3-methoxy-17-methylmorphinan called levomethorphan (LXM) is a potent narcotic analgesic. DXM has been widely abused in Korea due to its hallucinogenic effect in large doses; therefore, the health authorities have regulated its use as a psychotropic agent since 2003. As its abuse has been serious, a possibility that DXM would be smuggled into Korea has also increased. Moreover, it has been suspected that there was the possibility of the adulteration or substitution of DXM with LXM due to their chemical similarities. Therefore, it was necessary for us to establish the enantiomeric separation of DXM and LXM. In this study, a liquid chromatographic method using a chiral column capable of separating stereoisomers of DXM as well as analyzing the major metabolites of DXM, 3-methoxymorphinan, 3-hydroxymorphinan, and 17-hydroxymethylmorphinan was developed. The validation of a method was studied through repeatability of retention times. Using this method, 32 confiscated DXM samples were analyzed to identify the enantiomers of DXM. As a result, DXM was detected in all samples and there was no evidence of the adulteration or substitution of DXM with LXM. Nevertheless, the stereochemical analysis of DXM and LXM is important not only to identify starting materials for illegal drug manufacture but also to understand the trends of abused drugs.     

血液和脑脊液中利多卡因的气相色谱-质谱检测研究

目的建立血液和脑脊液中利多卡因的气相色谱-质谱联用定性、定量检测方法。方法血液或脑脊液盐酸酸化后,氢氧化钠碱化(pH=9),乙醚提取,氮气流下挥干,乙醇定容,气相色谱-质谱联用仪分析,选择离子监测模式检测(86,58,72,87),定性、定量检测血液和脑脊液中利多卡因。结果血液和脑脊液中利多卡因的线性范围为1.0～60.0μg·mL-1(r=0.9999),检出限为0.02μg·mL-1(S/N=3),加样回收率为85%～103%,麻醉致死犬血液和脑脊液中检出利多卡因,结果满意。结论该法选择性好,干扰少,灵敏,准确,可用于生物体液中利多卡因的定性和定量检测。     

对廉政文化建设的几点思考

胡锦涛同志在党的十七大报告中首次使用党与腐败水火不相容这样的铿锵之词,显示了拥有7300多万名党员的中国共产党面对腐败的坚决态度。胡锦涛总书记说:对任何腐败分子,都必须依法严惩,决不姑息!、确保权力正确行使,必须让权力在阳光下运行。在构建社会主义和谐社会这一关键时期,解决腐败问题的重要任务是建设廉政文化。     

略论儒家思想中的“君子”人格价值理想

人们的价值取向,不仅表现在对当今现实的价值关系的选择上,还表现在未来理想价值目标的确定上.儒家学说对人的价值理想追求是以"君子"为标准,儒家学说中认为"君子"应当具备"文质彬彬"的素质结构、"重义轻利"的价值观念、"可受大任"的责任能力、"和而不争"的处世态度、"执两用中"的思维方式.儒家这种"君子"人格特征的价值追求对中华民族性格的形成与发展有着重要的影响.     

Age estimation of Korean adults by occlusal tooth wear

The aim of the present study was to evaluate the validity of the modified Kim's scoring system as a practical method of recording occlusal tooth wear and estimating age. For this purpose, 1092 pairs of maxillary and mandibular full-arch casts were randomly selected, scored, and analyzed. The results showed that the modified Kim's scoring system had excellent reliability, and that occlusal tooth wear had a positive correlation with age. Tooth wear scores of all teeth except the two lower central incisors were higher in males than in females. Calculating tables for age estimation were designed by multiple linear regression analysis. Estimated ages were within +/-5 years of actual ages in 63.5% of male subjects, and 64.0% of female subjects. The accuracy of age estimation was increased when the subjects were divided into two age groups and data were re-analyzed. Collectively, it was shown that the modified Kim's scoring system is a reliable and accurate method for age estimation, and that the data from these 1092 individuals can be used as a standard for age estimation of Korean adults.