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Current forensic DNA profiling methods rely on the analysis of samples at specialised laboratories with an average turnaround time of several days. The ability to rapidly determine a partial profile of short tandem repeats at the point-of-arrest would be of great benefit to police forces around the world, for example enabling a suspect to be rapidly included or excluded from an investigation. We have developed a homogeneous PCR method for the interrogation of STR loci utilising fluorescent oligonucleotide probes and melting curve analysis. Alleles of the D18S51, TH01 and D8S1179 loci were differentiated and identified on the basis of target length and probe melting temperature. Assay performance was evaluated by comparing melting peak data with the AmpFlSTR® SGM Plus® system. The method is compatible with direct analysis of unpurified buccal swab samples, enabling a partial STR profile to be generated within 1 h.  相似文献   
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Over time, many fields of work - law, medicine, and teaching - matured from informal bodies of knowledge and skills, passed from one practitioner to another, into professions. In the process each began enumerating and affirming their intellectual and practical roots. Each also began testing practitioners to insure comprehension of relevant knowledge and an ability to demonstrate relevant skills. Family mediators in Canada have moved in this direction. In the United States, people who mediate interpersonal disputes also feel pressured to take additional steps to assure the quality of our work. This article summarizes what mediation organizations in the United States have done and could do to vouch for work in our field. But, taking additional steps calls for a clearer understanding of what a mediator should know and what they are expected to do. These two critical pieces of information remain nebulous. So, this article goes beyond describing ways of insuring accountability by also describing a recently completed job analysis, a tool frequently used in other fields of work to describe the skills and knowledge relevant to a particular job.  相似文献   
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In current armed conflicts around the world, over 90 per cent of casualties are civilians. This article reviews medical and anthropological evidence of the psychosocial effects of extreme experiences such as torture, mutilation, rape, and the violent displacement of communities. The consequences for women and children are considered in particular. The author argues that the social development programmes of non-governmental development organisations should be extended to support social networks and institutions in areas of conflict, and ends by giving guidelines for mental health promoters working in traumatised communities.  相似文献   
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The family functioning of 30 nonhandicapped and 30 learning handicapped adolescents and their parents was examined. Measures of adaptability, cohesion, and communication were taken from the parent and the adolescent perspectives. Parent and adolescent perspectives on these areas of functioning were analyzed with a cluster analytic technique, which resulted in five distinct profiles of family functioning. These statistical groupings were confirmed by information gathered through participant observation from an accompanying investigation. The nature of the five clusters confirmed the existence of similar family functioning across the nonhandicapped and learning handicapped groups. Additionally, variations in reaction and adjustment to the amount of structure in the family environment by different families was documented. The importance of considering adolescent and parent perspectives separately was highlighted.Received degree from University of California, Riverside. Research interests are in the area of the social development of at-risk or mildly handicapped children and adolescents in school and family settings.Received degree from Teachers College, Columbia University. Research interests in social competence and family relations of learning handicapped populations as well as the development of family, community, and school partnerships.  相似文献   
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A two-year collaboration among researchers, practitioners, and advisers from the major national organizations of mediators produced a job analysis relevant to mediators involved in interpersonal disputes (i.e., divorce, community, formal parent-child mediation, etc.). One byproduct of the job analysis is an extensive list of the knowledge areas and skills important to effective job performance. This essay defines the knowledge and skill areas that emerged from the analysis.  相似文献   
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Global brands remain under increasing pressure to ensure labor standards and codes of conduct are met by their suppliers. Little is known about how this is addressed by lower tier suppliers. We investigate whether, and how, occupational health and safety standards permeate down the computer industry value chain. We compare first and second tier suppliers' engagement with a private voluntary industry code, the Electronic Industry Code of Conduct, and the publicly regulated European Union Directive on the Restriction of Hazardous Substances. We find the industry code absent at the lower tier, yet second tier suppliers do implement the European Union Directive. This is achieved without support from public agencies or global value chain linkages. Our findings question the emphasis placed on chain governance in studies of labor compliance in global value chains, and suggest that alternative and complementary approaches may be required for effective labor compliance throughout the value chain.  相似文献   
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Largey G 《Society》1977,14(5):57-59
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