Segmental determination of ethyl glucuronide in hair: a pilot study

Ethyl glucuronide (EtG) is a minor metabolite of ethanol. Its detection in hair is more and more studied in both clinical and forensic context for the purpose of alcohol abuse monitoring. In this pilot study, hair specimens from 15 patients included in a treatment program after alcohol abuse cessation, were segmented and analyzed for EtG. The results were then compared to their self-reported past alcohol consumption and to their blood biomarkers values (GGT, MCV, ASAT, ALAT). EtG concentrations measured in hair varied from 8 to 261 pg/mg. The pattern of EtG concentration detected in the different hair segments matched with the drinking history of patients, displaying variations (increase and decrease) in alcohol consumption and also time of cessation. Results also demonstrated the existence of a significant correlation (r(p)=0.5357; p=0.0390) between EtG concentration in hair and the amount of alcohol intake. Variations in the EtG concentrations with respect to hair segments may provide an overview of the drinking history of patients. Moreover, EtG concentration in hair may help to estimate the daily alcohol intake.     

The social foundations of global production networks: towards a global political economy of child labour

The resilience of the problem of child labour in the global economy has been amply documented, but, we suggest, the reasons for this situation have not yet been fully captured in the associated debates. Our aim is to advance a way of thinking about those forms of child labour which occur in the context of global production networks (gpns), and to contend that greater attention must be paid to the organisation and functioning of gpns, and the social foundations on which they rest, if we are to grasp more fully the conditions and processes which facilitate the persistence and evolution of child labour. The way of thinking we propose is rooted in the concept of ‘adverse incorporation’ in the global economy, which we develop by drawing together currents in gpn analysis and poverty research to explore the commercial and social dynamics in gpns which give rise to these forms of labour exploitation. We illustrate our arguments with reference to the garments industry in New Delhi, India.