“Sex change” in skeletal remains: Assessing how heat-induced changes interfere with sex estimation

The true impact of heat-induced changes in human bone regarding their sex estimation has not been comprehensively documented having a potentially negative impact on forensic anthropology. The objective of this paper was to evaluate how heat exposure affects sex estimation based on both morphological and metric features. The study focused in both low-to-medium intensity burns and high intensity burns. Selected sexually dimorphic features were analysed in 51 experimentally burnt skeletons from the 21st Century Identified Skeletal Collection. Bones were burnt to maximum temperatures between 450 °C and 1050 °C achieved after 75 to 257 min. Morphological methods tested in this study comprised the recommendations for hipbone features from Buikstra and Ubelaker (1994) and from Bruzek (2002). On the other hand, metric references tested here were the ones from Wasterlain (2000), Curate et al. (2016) and Gonçalves et al. (2013) focused on the humerus, femur, calcaneus and talus. Agreement was tested with Gwet’s AC1 test and was further assessed by calculating the relative amount of perfect agreements. Results demonstrated that heat-induced changes affected not only the scoring of morphological features burnt at high temperatures but also the scoring of features burnt at lower intensities. On the other hand, metric features were only considerably affected in high intensity burns, no major changes being documented for low-to-medium intensity burns. For low-to-medium intensity burns, the Bruzek and Curate et al. methods revealed a better agreement between the pre- and post-burning scores. For high intensity burns, better agreement was obtained by using the Bruzek (2002) and Gonçalves et al. (2013) methods. As expected, heat-induced warping, fracture and metric change had a major impact on the pre- and post-observations’ agreement. Contrary to what has been systematically assumed over the years, this impact is also quite substantial in bones burnt at low-to-medium burn intensities so caution is advised during the analysis of this kind of burnt skeletal material.     

Molecular genetics of sudden cardiac death

Sudden cardiac death (SCD) is one of the most common causes of death. An important number of sudden deaths, especially in the young, are due to genetic heart disorders, both with structural and arrhythmogenic abnormalities. In recent years, significant advances have been made in understanding the genetic basis of SCD. Identification of the genetic causes of sudden death is important because close relatives are also at potential risk of having a fatal cardiac condition. A comprehensive post-mortem investigation is vital to determine the cause and manner of death and provides the opportunity to assess the potential risk to the family after appropriate genetic counselling. In this paper, we present an update of the different genetic causes of sudden death, emphasizing their importance for the forensic pathologist due to his relevant role in the diagnosis and prevention of SCD.     

Populism,ontological insecurity and Hindutva: Modi and the masculinization of Indian politics

Abstract

In an era increasingly defined by insecurity and populist politics, India has emerged as a forceful ontological security provider under the leadership of Marendra Modi. If ontological security is about finding a safe (imagined) haven, then ontological insecurity is about the lack of such a space in narrative terms. Drawing on Lacanian understandings of ‘the imaginary’ as something that can fill and naturalize this lack of space, the article is concerned with how memories, places and symbols of narrative identity constructions are used in populist discourse. More specifically, it attempts to understand the relationship between ontological insecurity and the imaginaries of populist politics in India. In so doing, it argues that the re-invention of ‘nationhood’, ‘religion’ and ‘Hindu masculinity’ along gendered lines has created a foundation for governing practices aimed at ‘healing’ a number of ontological insecurities manifest in Indian society. It specifically looks at how the Modi doctrine has formulated and expanded its foreign policy discourse into one that privileges populist narratives of nativism, nationalism and religion as forms of ontological security provision at home and abroad, but also how everyday practices can challenge such narratives, thus allowing different imaginaries of the Indian state.     

Sarcomeric gene mutations in sudden infant death syndrome (SIDS)

In developed countries, sudden infant death syndrome (SIDS) represents the most prevalent cause of death in children between 1 month and 1 year of age. SIDS is a diagnosis of exclusion, a negative autopsy which requires the absence of structural organ disease. Although investigators have confirmed that a significant percentage of SIDS cases are actually channelopathies, no data have been made available as to whether other sudden cardiac death-associated diseases, such as hypertrophic cardiomyopathy (HCM), could be responsible for some cases of SIDS. The presence of a genetic mutation in the sarcomeric protein usually affects the force of contraction of the myocyte, whose weakness is compensated with progressive hypertrophy and disarray. However, it is unclear whether in the most incipient forms, that is, first years of life, the lack of these phenotypes still confers a risk of arrhythmogenesis. The main goal of the present study is to wonder whether genetic defects in the sarcomeric proteins, previously associated with HCM, could be responsible for SIDS. We have analysed 286 SIDS cases for the most common genes implicated in HCM in adults. A total of 680 mutations localised in 16 genes were analysed by semi-automated matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry (MALDITOF-MS) using the Sequenom MassARRAY(?) System. Ten subjects with completely normal hearts showed mutated alleles at nine of the genetic variants analysed, and one additional novel mutation was detected by conventional sequencing. Therefore, a genetic mutation associated with HCM may cause sudden cardiac death in the absence of an identifiable phenotype.     

The role of a Proof of Concept Center in a university ecosystem: an exploratory study

The Proof of Concept phase in university technology transfer is considered to be critical for the success of both licensing and the creation of spin-off companies. In the United States, Proof of Concept Centers are emerging as successful structures to address the challenges of this phase. In this paper, we present a framework to assess the role for such a structure in a university ecosystem. The framework is built from previous references that we use to explicitly link the features of Proof of Concept Centers with the challenges of the Proof of Concept phase, and establish their specific contributions to the overall technology commercialization efforts of a university. We illustrate the application of this framework in a case study of the University of Coimbra, in Portugal, and develop a characterization that is representative of the role that a Proof of Concept Center can play in comparable university ecosystems that feature conventional technology commercialization structures, and struggle with the challenges of the Proof of Concept phase. Our study suggests that there is in fact a possible role for a Proof of Concept Center in the regional ecosystem of the University of Coimbra, with a potentially very relevant impact in the technology commercialization process, through networking outside academia and research environments, funding of Proof of Concept activities, and technology entrepreneurship education for the development of entrepreneurial skills for researchers.     

Uncivil society and social policies in Brazil: The backlash in the gender,sexual, and reproductive rights and ethnic and racial relations fields

This paper analyzes how dynamics between Brazil's right-wing populist government and civil and uncivil organizations affected the role of civil organizations, especially rights-based ones, and Brazil's democratization process. These dynamics contributed to stripping policies of their progressive nature and rejecting the values of diversity, freedom, and equality. Our analysis relies on the inhabited institutions approach to comprehend the role of action, interaction, and meaning in institutionalized spaces. We analyzed two policy fields—gender, sexual, and reproductive rights, and ethnic and racial relations—through documents and in-depth interviews. Our analysis shows that Bolsonaro's government mobilized mechanisms related to institutional changes, the replacement of actors, and their interactions to inhibit civil society organizations' influence in policy formulation and provision and strengthen the participation of uncivil groups, thereby legitimating conservative ideas and discourses, and closing civic space for NGOs with rights-based agendas.     

Policy diffusion in subnational governments: State–local relationships in the Brazilian education policy

Intergovernmental relations play a key role in policy diffusion among constituent units. Federal governments have adopted different mechanisms to guarantee minimum standards across the countries, but historical trajectories and widely shared policy ideas are also mentioned as relevant in diffusion processes. This paper focuses on the influence of federalism in policy diffusion at the subnational level in Brazil. The 1988 Constitution consolidated decentralization of the Brazilian education policy but required cooperation between states and municipalities. The lack of a national definition resulted in a great variety of cooperative programmes and coordination arrangements, allowing the identification of similarities and differences among their diffusion processes. This article shows that state governments are the main policy-makers regarding cooperation, which highlights that the role of the federal government does not entirely explain these processes. Nevertheless, policy trajectories and the movement of ideas and people municipalities were keys for policy diffusion.     

Family Functioning and Adolescent Internalizing and Externalizing Problems: Disentangling between-, and Within-Family Associations

Journal of Youth and Adolescence - Adolescence is often a period of onset for internalizing and externalizing problems. At the same time, adolescent maturation and increasing autonomy from parents...     

Business,social responsibility,and corruption

This paper explores the role of corporate social responsibility and the reporting thereof in the fight against corruption. A special focus is laid on the international endeavors to improve transparency through reporting, and the paper elaborates extensively on the United Nations Global Compact (UNGC), the Organisation for Economic Co‐operation and Development (OECD) Guidelines for Multinational Enterprises and the Global Reporting Initiative's (GRI) Sustainability Reporting Guidelines. Voluntary initiatives, such as the UNGC, the OECD guidelines, and the GRI guidelines, are considered to play an important role in providing the trust‐based informal social norms, without which markets and societies cannot function. Copyright © 2012 John Wiley & Sons, Ltd.     

Security,subjectivity and space in postcolonial Europe: Muslims in the diaspora

Abstract

In this article, we call into question the assumptions that undergird conceptions of boundary, territory, community and ethno-cultural belonging in the constitution of European security. Both the term ‘human security’ as defined by development and human rights scholars and ‘securitisation’ as conceptualised by critical security studies concern the socio-psychological aspects of security. Yet, few attempts have been made to seriously discuss the psychological effects of securitisation on subjectivity and space. There is, as we will argue, a tendency in much literature to use concepts of ‘existential security’, ‘fear’, ‘needs’ and the ‘politics of belonging’ – obviously connected to the human mind and individual emotionality – without much space being devoted to the investigation of these concepts in terms of socio-psychological processes. We intend to fill this gap by discussing security and securitisation in terms of the psychology of subjectivity and space among young Muslims in Europe. Our principal argument is that through openness to the political psychology of subjectivity and space, and the (de)securitisation of both, we are able to develop more adequate maps of the European experience of danger and opportunity.