The effect of 1,2-indanedione,a latent fingerprint reagent on subsequent DNA profiling

The compound 1,2-indanedione was recently introduced in our laboratory as an operational reagent for developing latent fingerprints on porous surfaces. As part of the reagent implementation, a study was carried out in order to determine whether either of the two operational 1,2-indanediones formulations interferes with further DNA profiling. Both formulations are based on HFE7100 solvent. One is acidic and the other neutral. In a controlled experiment, known donors attached stamps to envelopes by licking them. The stamped envelopes were initially treated with either one indanedione formulation or the other, and DNA was then extracted for STR typing. No differences were observed between the STR profiles obtained from treated and untreated stamps and envelopes, indicating that 1,2-indanedione does not adversely affect the extraction and subsequent amplification of the STRs examined. However, preliminary results indicate that potential DNA analysis depends on the time interval between the indanedione treatment and DNA extraction as no DNA can be recovered six days following treatment. For this reason, it is strongly recommended to extract DNA from treated items of evidence as soon as possible after indanedione treatment.     

STR analysis of artificially degraded DNA-results of a collaborative European exercise

Degradation of human DNA extracted from forensic stains is, in most cases, the result of a natural process due to the exposure of the stain samples to the environment. Experiences with degraded DNA from casework samples show that every sample may exhibit different properties in this respect, and that it is difficult to systematically assess the performance of routinely used typing systems for the analysis of degraded DNA samples. Using a batch of artificially degraded DNA with an average fragment size of approx. 200 bp a collaborative exercise was carried out among 38 forensic laboratories from 17 European countries. The results were assessed according to correct allele detection, peak height and balance as well as the occurrence of artefacts. A number of common problems were identified based on these results such as strong peak imbalance in heterozygous genotypes for the larger short tandem repeat (STR) fragments after increased PCR cycle numbers, artefact signals and allelic drop-out. Based on the observations, strategies are discussed to overcome these problems. The strategies include careful balancing of the amount of template DNA and the PCR cycle numbers, the reaction volume and the amount of Taq polymerase. Furthermore, a careful evaluation of the results of the fragment analysis and of automated allele calling is necessary to identify the correct alleles and avoid artefacts.     

Genipin--a novel fingerprint reagent with colorimetric and fluorogenic activity

Genipin, the hydrolytic product of geniposide, which is extracted from gardenia fruit, shows good potential as a fingerprint reagent. It develops latent fingerprints on paper as blue impressions with good contrast and resolution. Even very faint impressions that are barely visible in ambient light will fluoresce brightly upon illumination at ca. 590 nm and are best viewed with a barrier filter above 630 nm. Potential advantages of genipin are the combination of colorimetric and fluorogenic activity in one reagent as well as its being a safe and environmentally friendly natural product.     

The reciprocal dynamics of organizing and sense‐making in the implementation of major public‐sector reforms

Abstract: Drawing on a longitudinal study from the early years of implementation of health‐care networks in Quebec, this article describes how public‐sector managers deal with complex challenges when both organizational structures and organizational strategies are radically transformed simultaneously. The new organizations studied had to completely re‐shuffle roles and responsibilities of their management teams while making sense of their new mandate of developing a population‐focused approach to health problems – all the time maintaining day‐to‐day operations. The four health‐care networks studied proceeded somewhat differently to meet these reciprocal challenges. The study reveals the importance of balancing organizing initiatives (focused on structures) with “sense‐making” initiatives (focused on strategies), of developing capacities for sense‐making through the creation of key “sense‐maker/sense‐giver” positions whose occupants are able to ensure that conceptual activities engage people working at different levels, even as organizational structures are in flux, and of mobilizing external constraints and influences as opportunities and resources in sense‐making and organizing. Sommaire : Se fondant sur une étude longitudinale des premières années de la mise en œuvre des réseaux de soins de santé au Québec, cet article décrit la manière dont les gestionnaires du secteur public font face à des défis complexes, alors que les structures et les stratégies organisationnelles sont radicalement transformées simultanément. Les nouveaux organismes étudiés ont dû complètement remanier les rôles et les responsabilités de leurs équipes de gestion et comprendre leur nouveau mandat d'élaborer une approche axée sur la population pour ce qui est des problèmes de santé, tout en maintenant leurs activités au jour le jour. Les quatre réseaux de soins de santéétudiés ont travailléà relever ces défis réciproques d'une manière assez différente. L'étude révèle l'importance de trouver un équilibre entre les initiatives consistant à organiser (axées sur les structures) et les initiatives consistant à interpréter les faits (axées sur les stratégies) ; de perfectionner les capacités à interpréter les faits grâce à la création de postes clés d'«interpréteurs de faits», dont les titulaires veilleraient à ce que des activités conceptuelles fassent intervenir les gens travaillant à différents niveaux même lorsque les structures organisationnelles fluctuent continuellement; et enfin de tirer parti des contraintes et influences externes comme autant d'occasions et de ressources pour interpréter et organiser les faits.     

The influence of bankruptcy law on equity value of financially distressed firms: A European comparative analysis

The reaction of stock prices to bankruptcy filing has been frequently analysed in the financial literature. In this paper we adopt a different approach to that of traditional study, and endeavour to determine whether the reaction of markets is conditioned by the orientation of bankruptcy law. Our results lead us to conclude that it is actually the type of bankruptcy law that conditions the valuation of firm's stocks. We have also found that the drop in share value is greater in creditor-oriented systems, while the negative returns are lower in debtor-oriented systems.     

The Politics of Security and Technology in Switzerland

Technologies play crucial roles in security politics. In a recent push to understand the dynamic interplay between technologies and politics, IR scholars increasingly draw on reflexive research traditions. The aim is to understand the social and political practices that influence the shape, design and use of security technologies instead of assuming that technologies have linear, independent effects on politics. This SPSR debate draws on this new perspective and applies it to topics salient in Swiss public debate. Its contributions analyze how cybersecurity, predictive policing, drones, artificial intelligence, targeted sanctions, urban design and spyware are deliberated, negotiated, programmed and critiqued in Switzerland. They chart different analytical avenues with which to address the recursive and non‐linear relationship between security politics and technologies, and, by familiarizing readers with the tenets and diversity of reflexive political science research, seek to give that longstanding scholarly research tradition better visibility in the Swiss political science community.     

“SMART” Photovoice agricultural consultation: increasing Rwandan women farmers' active participation in development

Through two case studies, this paper evaluates the value of the feminist visual methodology Photovoice as an interactive consultation tool with rural Rwandan women working in agriculture. This exploratory study suggests that it is possible, through an adapted Photovoice process, to engage and empower women in the production of information about what is most relevant to them, and reach and engage practitioners and officials through an exhibition of participants' photographs and captions. This confirmation of Photovoice's applicability with rural women in the generation of information that captures the attention of stakeholders demonstrates its potential for reproducibility in other development contexts.

Consultation agricole Photovoice « SMART » : accroître la participation active des agricultrices rwandaises au développement

À travers deux études de cas, cet article évalue la valeur de la méthodologie visuelle féministe Photovoice comme outil interactif de consultation avec des rwandaises rurales travaillant dans l'agriculture. Cette étude exploratoire suggère que cette utilisation est possible, à travers un processus Photovoice adapté, afin de mobiliser et d'autonomiser les femmes dans la production d'informations sur ce qui est le plus pertinent pour elles, et de toucher et de mobiliser les praticiens et les fonctionnaires en leur présentant une exposition des photos et des textes explicatifs créés par les participantes. Cette confirmation de l'applicabilité de Photovoice parmi des femmes rurales en vue de générer des informations qui attirent l'attention des parties prenantes démontre le potentiel que présente cette méthodologie d’être reproduite dans d'autres contextes de développement.

Consultas agrícolas por Photovoice “smart”: aumentando la participación activa de campesinas ruandesas en el desarrollo

Apoyándose en dos estudios de caso, el presente artículo evalúa la metodología visual feminista Photovoice como método de consulta interactiva a mujeres campesinas ruandesas que trabajan en la agricultura. Este estudio exploratorio revela la posibilidad de involucrar y de empoderar a las mujeres, a través de un proceso de Photovoice adaptado, destinado a producir información en torno a aquello que resulta más relevante para ellas; asimismo, dicho proceso permite involucrar a los operadores y a los funcionarios mostrándoles las fotografías de las participantes con sus correspondientes pies de foto. Una vez confirmado el valor de utilizar Photovoice para generar información entre mujeres campesinas, capturando, además, la atención de los actores principales, queda demostrado el potencial que tiene su replicación en otros contextos de desarrollo.

Consulta agrícola através da metodologia Photovoice “SMART”: aumentando a participação ativa de mulheres produtoras rurais de Ruanda no desenvolvimento

Através de dois estudos de caso, este artigo avalia a metodologia visual feminista Photovoice enquanto ferramenta de consulta interativa com mulheres ruandesas rurais que trabalham na agricultura. Este estudo investigativo sugere que é possível, através do processo Photovoice adaptado, engajar e empoderar as mulheres na produção de informações sobre o que é mais relevante para elas, e ter acesso e engajar profissionais e funcionários através da exposição de fotos de participantes e legendas. Essa confirmação da aplicabilidade do Photovoice com mulheres de áreas rurais na geração de informações que capturem a atenção de stakeholders demonstra seu potencial para a reprodução em outros contextos de desenvolvimento.