Validity of Demirjian and Willems methods for dental age estimation for Malaysian children aged 5–15 years old

BackgroundOne of the most commonly used method for dental age assessment is the method reported by Demirjian and coworkers in 1973. It was later modified by Willems and coworkers whereby they “performed a weighted ANOVA” in order to adapt the scoring system.AimTo evaluate the applicability of Demirjian and Willems methods for dental age estimation for Malaysian children and to correlate the accuracy of the findings with the chronology of tooth development of premolars and second molars.Materials and methodsA total of 991 dental panoramic radiographs of 5–15-year-old Malaysian children were included in the study. The mean Demirjian and Willems estimated ages were compared to the mean chronological age.ResultsThe mean chronological age of the sample was 10.1 ± 2.8 and 9.9 ± 3.0 years for males and females respectively. Using the Demirjian method, the mean estimated dental age was 10.8 ± 2.9 years for males and 10.5 ± 2.9 years for females. For Willems method, the mean estimated age was 10.3 ± 2.8 years males and 10.0 ± 3.0 years respectively.ConclusionsWillems method was more applicable for estimating dental age for Malaysian children. Overestimation in Demirjian method could be due to advanced development of second bicuspids and molars.     

Understanding Havel?

The presented article tries to make sense of Václav Havel, a man of many qualities and professions yet not a professional in the conventional sense of the word. The aim is to offer deeper insight into diverse cognitive elements which formed Havel's political reasoning and attitudes. The idea is to provide an alternative interpretation and get beyond the customary explanations expressed through traditional IR language seeing Havel as a dissident idealist who was pushed by some realist impulses to clearly define real political and later also geopolitical stands. In doing so, the article is divided into three parts. The first part discusses conceptual frameworks (rather than a single framework) within which Have saw and understood the political world. The middle part examines Havel's political agenda, namely the issues of the return to Europe, the German question, and relationships with Russia, the United States and toward multilateral institutions. The final part that utilizes primary data obtained through personal interviews with many Havel's close collaborators presents two faces of Václav Havel: the dramatist and the ideologue.     

The US–Russian security ‘reset’: implications for Central-Eastern Europe and Germany

Abstract

The article examines the reactions of selected European states to the US-performed ‘reset’ in relations with Russia and explores the ways in which they have been adapting to the new set-up. The article is divided into three parts: after the discussion of the substantive continuity and limited change in US foreign and security policy (USFSP), the multilateral and bilateral dimensions of USFSP procedure are examined through John Ruggie's theoretical observations. The second part of the article deals with implications of the USFSP for Central-Eastern European countries. This part begins with a discussion of Russian attempts to wheedle Europe into embracing its plans for new European security architecture. The next section sheds light on the unexpected process of strategic realignment of the region (USA/NATO/EU/CSDP) and simultaneous transformation of the special relationship with the USA into ‘normal life’. The third part of the article tackles the implications of heightened US–Russian bilateralism for Germany. Authors' findings, many of them based on conducted elite interviews, suggest the contrary process, namely Germany's strengthened multilateral commitment to the EU and specifically to European Security and Defence Policy, limiting the bilateral option to energy trade with Russia. What follows are concluding remarks.     

Fast quantification of 11-nor-Δ9-tetrahydrocannabinol-9-carboxylic acid (THCA) using microwave-accelerated derivatisation and gas chromatography–triple quadrupole mass spectrometry

A rapid and sensitive determination of cannabinoids in urine is important in many fields, from workplace drug testing over toxicology to the fight against doping. The detection of cannabis abuse is normally based on the quantification of the most important metabolite 11-nor-Δ9-tetrahydrocannabinol-9-carboxylic acid (THCA) in urine. In most fields THCA needs to be present at a concentration of exceeding 15 ng/mL before a positive result can be reported.The method described in this paper, combines a 4 min GC–MS/MS method with a fast sample preparation procedure using microwave assisted derivatisation in order to complete the quantification of THCA in urine in 30 min, using only 1 mL of urine.The method is selective, linear over the range 5–100 ng/mL and shows excellent precision and trueness and hence, the estimated measurement uncertainty at the threshold level is small. The method also complies with applicable criteria for mass spectrometry and chromatography. Therefore the method can be used for rapid screening and confirmatory purposes.     

Coping with U.S. and EU's challenges? Strategic confusion in the Czech foreign and security policy

This article traces developments in the Czech political elite's thinking about structural changes that the region and the country have experienced during the last several years. It is argued that two parallel, external structural constraints have significantly shaped decisions of the Czech political elite as the country has, once again, proven to be an ostensibly “reactive state”. These structural constraints have been the ongoing U.S. recalibration of its grand strategy as well as the financial crisis with a systemic challenge to the European political project in which fiscal and monetary issues have largely replaced previous criticism of the Constitutional Treaty and then the Reform Treaty. It is argued that these developments have posed a notable problem for two predominant ideological convictions present in the Czech political thinking – Atlantism and Europeanism, as neither of them has offered readily answers to deal with such a challenge. As will be shown, this mutually reinforcing dual challenge has further exacerbated previously existing Czech government's lack of political vision, and resorted to a political mentality which has contained elements of denial, rationalization, and political resignation.     

Age-related distribution of longitudinal pre-strain in abdominal aorta with emphasis on forensic application

It is a well-known fact that the length of an artery in situ and the length of an excised artery differs. Retraction of blood vessels is usually observed. This pre-tension plays crucial role in arterial biomechanics. It augments an artery wall load-bearing capacity. This paper presents the longitudinal pre-strain of the human aorta as an index of human age. The length of abdominal aortas was measured during autopsies before and after segment resection. The longitudinal pre-strain was calculated in 130 donors; 100 male and 30 female bodies. The pre-strain was defined as the ratio between in situ length and the length after the excision. The mean pre-strain was found to be 1.18±0.10 for male and 1.14±0.10 for female sample (mean±standard deviation). The age in the male group was 41.6±15.9 years; and 47.7±17.7 years in the female group. Statistical analysis revealed the correlation coefficient between age and pre-strain r=-0.821 and r=-0.839 in male and female group, respectively. The analysis also confirmed close correlation between aortic circumference and age; and between circumference and pre-strain. Linear and power law regression equations were employed and prediction intervals were computed. The power law estimates the age more accurately than linear one model. Nevertheless, especially for small values of the pre-strain (aged individuals) the linear model can be advantageous.     

Research capacity building through twinning: experiences from a Danish–Malaysian twinning project

Twinning and its contribution to institutional capacity building in developing countries is the theme of an ongoing debate in Public Administration and Development. Unlike earlier contributions this article focuses on twinning in the context of research capacity enhancement. Using a 3 year Danish–Malaysian twinning research project as case our objective is to evaluate whether the general premises regarding a twinning project, as formulated by the Danish Development Cooperation Agency (Danida), appropriately support the twinning ambitions when the capacities in focus concern research. Besides institutional capacity building, twinning is expected to favour local ownership, involvement of the Danish resource base and continuing of cooperation after termination of funding. From 21 semi‐structured interviews with project participants it was found that although new research capacities had been gained, the prospects on continued cooperation are rather discouraging, both sides pointing to the lack of truly joint research experiences as the main reason. To care for this important incentive, the twinning premises are recommended to be modified to allow for the Northern resource base to advance its own research, and for Southern partner to demonstrate in‐house research capacities. Further, the North–South balance in project management needs to be more equal. This apart, the twinning premises appear sound. Copyright © 2007 John Wiley & Sons, Ltd.     

Methadone‐Related Deaths – Epidemiological,Pathohistological, and Toxicological Traits in 10‐year Retrospective Study in Vojvodina,Serbia

The number of methadone‐related deaths (MRDs) during a 10‐year period (2002–2011) in the region of Vojvodina, Serbia, was increased. The cases were evaluated according to epidemiological parameters, pathohistological findings, and toxicological screening. The majority of victims were men, aged from 20 to 38. Pathohistologically, the signs of acute focal myocardial damage were present in the heart of victims with drug abuse history shorter than 2 years, while both signs of recent and chronic focal myocardial damage were developed among victims with longer drug abuse history (2–5 years). In postmortem blood samples of 54.84% of victims, methadone was detected in combination with diazepam, both in therapeutic range. Alcohol was absent in most cases. Other detected drugs were antipsychotics and antidepressants in therapeutic concentrations. These findings raise the attention to the concomitant use of methadone and benzodiazepines with the need for further studies to clarify the mechanism of death in such cases.