Political Liberalism. Neutrality and the Political

Abstract. The paper examines the current discussion in liberalism around the issue of the "neutrality" of the state. It scrutinizes the "political liberalism" defended by John Rawls and Charles Larmore and shows that the consequence of their approach is to evacuate the dimension of "the political" from the idea of a well-ordered society. By presenting the exclusions existing in their model of liberal society as the product of free agreement resulting from rational procedures, "political liberals" offer us a picture in which antagonism, violence and power have only disappeared because they have been made invisible. The consequence is to leave liberalism unable to conceptualize power and antagonism. The paper concludes that there cannot be such a thing as a "neutral justification of the neutrality of the state" (Larmore 1987) and that a pluralist perfectionist perspective like the one proposed by Joseph Raz offers a more adequate way to envisage the specificity of modern pluralist democracy.     

Validation of short tandem repeats (STRs) for forensic usage: performance testing of fluorescent multiplex STR systems and analysis of authentic and simulated forensic samples

The amplification and typing conditions for the 13 core CODIS loci and their forensic applicability were evaluated. These loci are CSF1PO, FGA, TH01, TPOX, vWA, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, and D21S11. Results were obtained using the multiplex STR systems AmpFlSTR Profiler Plus and AmpFlSTR COfiler (Applied Biosystems, Foster City, CA), GenePrint PowerPlex (Promega Corporation, Madison, WI), and subsets of these kits. For detection of fluorescently labeled amplified products, the ABI Prism 310 Genetic Analyzer, the ABI Prism 377 DNA Sequencer, the FMBIO II Fluorescent Imaging Device, and the Fluorlmager were utilized. The following studies were conducted: (a) evaluation of PCR parameter ranges required for adequate performance in multiplex amplification of STR loci, (b) determination of the sensitivity of detection of the systems, (c) characterization of non-allelic PCR products, (d) evaluation of heterozygous peak intensities, (e) determination of the relative level of stutter per locus, (f) determination of stochastic PCR thresholds, (g) analysis of previously typed case samples, environmentally insulted samples, and body fluid samples deposited on various substrates, and (h) detection of components of mixed DNA samples. The data demonstrate that the commercially available multiplex kits can be used to amplify and type STR loci successfully from DNA derived from human biological specimens. There was no evidence of false positive or false negative results and no substantial evidence of preferential amplification within a locus. Although at times general balance among loci labeled with the same fluorophore was not observed, the results obtained were still valid and robust. Suggested criteria are provided for determining whether a sample is derived from a single source or from more than one contributor. These criteria entail the following: (a) the number of peaks at a locus, (b) the relative height of stutter products, and (c) peak height ratios. Stochastic threshold levels and the efficiency of non-templated nucleotide addition should be considered when evaluating the presence of mixtures or low quantity DNA samples. Guidelines, not standards, for interpretation should be developed to interpret STR profiles in cases, because there will be instances in which the standards may not apply. These instances include (a) a primer binding site variant for one allele at a given locus, (b) unusually high stutter product, (c) gene duplication, and (d) translocation.     

Population data on the thirteen CODIS core short tandem repeat loci in African Americans, U.S. Caucasians, Hispanics, Bahamians, Jamaicans, and Trinidadians

Allele distributions for 13 tetrameric short tandem repeat (STR) loci, CSF1PO, FGA, TH01, TPOX, VWA, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, and D21S11, were determined in African American, United States Caucasian, Hispanic, Bahamian, Jamaican, and Trinidadian sample populations. There was little evidence for departures from Hardy-Weinberg expectations (HWE) in any of the populations. Based on the exact test, the loci that departed significantly from HWE are: D21S11 (p = 0.010, Bahamians); CSF1PO (p = 0.014, Trinidadians); TPOX (p = 0.011, Jamaicans and p = 0.035, U.S. Caucasians); and D16S539 (p = 0.043, Bahamians). After employing the Bonferroni correction for the number of loci analyzed (i.e., 13 loci per database), these observations are not likely to be significant. There is little evidence for association of alleles between the loci in these databases. The allelic frequency data are similar to other comparable data within the same major population group.     

Le probléme des origines des Assemblées d'États: Réflexions méthodologiques à la lumière de l'histoire sud‐est européenne de l'institution

Summary

This paper examines the relations between republican and democratic forces in Restoration Spain. From the middle of the last century, republicanism was the political movement most clearly involved with the democratization of Spanish politics. After the collapse of the 1873 Republic, the republican movement went through a severe crisis which led to its fragmentation over issues both of principle (federalists against unitarists) and of practice (revolutionaries against reformists). Between 1873 and 1931 Spanish republicanism underwent a marked transformation. The old republicanism was characterized by the modes of political activity of the nineteenth century — the club, the committee, the masonic lodge. The new republicanism, on the other hand, emerged from the first decade of the present century clearly moving in the direction of the modern political parties which finally crystallized out in 1931. Together the Radical and the Reformist parties are a case‐study in the transition between the classical and the modern which perfectly exemplifies the hybrid nature of republican democracy.

Though Spanish republicanism was socially heterogeneous, embracing within its various parts elements of the upper and middle bourgeoisie, substantial sections of the petty, urban bourgeoisie, and a declining, but still numerous, section of the working class, it still needed an alliance with the socialists (the Conjunción of 1910). However, what was most notable about Spanish republicanism was its link with the intelligentsia; it was they who gave it its character and who made the greatest effort to integrate Spain into the most modern currents of European thought.