Validation of the Seratec® SeraQuant™ for the quantitation of prostate-specific antigen levels on immunochromatographic membranes

Abstract: Use of immunochromatographic membranes for the detection of prostate‐specific antigen (PSA) has become commonplace in forensic laboratories. Experiments were designed to test the newly developed Seratec^® SeraQuant? for accuracy, precision, and consistency in the quantitation of PSA. PSA standards were diluted with buffers and run on the instruments. Values obtained were examined for accuracy (was the correct value obtained?) and precision (were multiple sample values consistent?). To test for variation between instruments, large volumes of diluted PSA standard were run repeatedly on six units and the values obtained were plotted against the known PSA values to obtain a standard curve for each instrument. Fifty membranes having negative or weak positive results were then run on the six units, and the adjusted values were recorded and compared. Results of these experiments indicate that the instruments are accurate and precise in the quantitation of low levels of PSA.     

Der Fall Bautzen: Eine Netzwerkanalyse zur Entstehung digitaler Öffentlichkeiten

In autumn 2016, refugees and followers of the political right were caught up in a violent conflict in the Saxon town of Bautzen. The paper analyses how this event was discussed in the digital public. On the basis of Bruno Latour’s relational sociology it carries out a quantitative network analysis in order to understand the structural dynamics of Twitter as a discursive arena. It appears that the political debate of the event develops from unconnected partial publics via antagonistic battles of opinion up to closed echo chambers. In the case of Bautzen, Twitter works like a megaphone: the technology doesn’t contribute to intersubjective understanding but facilitates the distribution of personal constructions of reality.     

Medical and legal aspects of genital mutilation and circumcision part I: female genital mutilation (FGM)

Female genital mutilation (FGM) is considered to be against the law and against morality not only in Western countries, although a woman of age and able to consent may sometimes think differently. The procedure may have serious physical and emotional consequences for the girl or woman. Nevertheless there are attempts to justify the procedure with medical and hygienic pseudoarguments, ideology, freedom of religion, cultural identity and social adequacy. Outside the Western world, some people claim that religion and culture alone justify the practice. In Germany, parents can lose the right to determine the residence of their daughter, if she is faced with the risk of genital mutilation in order to prevent that the child or girl is taken to her home country. Genital mutilation as a gender-specific threat is recognized as a reason to grant asylum or prevent deportation. Proposals to make genital mutilation a separate punishable offence are presently discussed by the legislator.     

The relative indices of efficiency for selected methods of bloodstain analysis

Selected methods of analysis are compared with respect to man-hours, cost, and discrimination power. The methods are listed according to their efficiencies with Enzyme Group I System being the most efficient and Enzyme Group III System the least.     

Richard Rorty und die Reanimation des Pragmatismus im „Zeitalter der Komposition“

In recent years, pragmatism is experiencing a renaissance. Classic authors like George Herbert Mead, William James or John Dewey are entering sociological discussions and neopragmatistic approaches as the actor-network theory or the sociology of conventions are gaining influence. But under what social circumstances is the reanimation of pragmatism happening and what analytical use do pragmatistic tools have? In order to answer this research question the article develops a general model of social order that distinguishes between the states of collision, composition, institution and deconstruction. On this basis, a social diagnosis is articulated, making the currency of the pragmatistic vocabulary understandable. It appears that pragmatism is focused on experimental, creative and hybrid processes of becoming that are typical for the current age of composition. With the help of the often neglected Richard Rorty, the added value of a pragmatistically-informed sociology is shown in an exemplary manner. Therefore, Rorty is introduced as an integrating figure of pragmatistic ideas, from which important impulses for a Darwinian, relational, symmetrical and ironically-engaged sociology could exert.     

Medical and legal aspects of genital mutilation and circumcision. Part II: Male circumcision

In the last few years, male circumcision has become the subject of controversial discussion. On the one hand, medical and hygienic arguments, ideology, freedom of religion, cultural identity and social adequacy are claimed by those supporting male circumcision. On the other hand, the justification of this practice also has to be critically scrutinized just as the question whether the parents have the right to consent to the operation. Today, opinions range from those who claim that religion and culture alone justify the practice to those who consider circumcision of minors unable to give their consent as bodily injury subject to punishment. In contrast to female genital mutilation, most positions do not postulate that circumcision violates morality. If the person concerned is able to give his consent, freedom of religion may also justify circumcision after weighing its pros and cons as well as its risks and potential side effects.     

Public Enterprises and Canadian Foreign Economic Policy

To what extent can public enterprises serve as instruments ofpolicy enabling the federal government to assert a measure ofcontrol over Canada's foreign economic relations? This articlepresents an overview of public enterprises in Canada and highlightsthe special features of the Canadian political economy whichdifferentiate it from other advanced industrial economies. Theactivities of the Canada Development Corporation and CanadianNational Railways are analyzed in terms of whether they reinforceor undermine the federal government's authority in foreign economicpolicymaking. It appears that the relative autonomy of publicenterprises from government controls, most pronounced in thecase of commercial enterprises operating in competitive markets,fragments decisionmaking. Given that governmental power in Canadais already fragmented due to competitive federalism, and giventhe expanded activities of provincial public enterprises inrecent years, a lack of direction over the "subgovernment" offederal public enterprises compounds the difficulties for Ottawato conduct a coherent, foreign economic policy.     

Finanzmarktwächter: Über die Synchronisation von Politik und Ökonomie

From the perspective of an actor-centered theory of differentiation, the article explores how political decisions and developments in a financialized economy are temporally coordinated. For the purpose of answering this research question, the paper develops a four-dimensional heuristic model capable of capturing societal differences regarding time. By sketching the concept of a “hybrid organization”, it models an arena in which such differences may be bridged. Assuming this theoretical perspective, the paper examines the German Federal Financial Supervisory Authority (BaFin) in order to scrutinize how and to which extent the targeted synchronization of politics and finance is achieved. This qualitative organizational study shows that the BaFin accomplishes its function only to a limited degree: Global flows of capital and bureaucratic provisions erode its leverage as a supervisor of the financial market, and the accelerated dissemination of financial derivatives make it look like a lethargic authority. Thus, from a sociological point of view further structural alterations at the interface of the political and economic sphere are required in order to lower the risk of economic crises and post-democratic developments.