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Allele frequencies, together with some parameters of forensic interest were estimated for nine STRs included in the AmpF/STR Profiler kit (CSF1PO, D3S1358, D5S818, D7S820, D13S317, FGA, TH01, TPOX and vWA) in a sample of 215 unrelated individuals from Cartagena (Colombia). For all loci, no significant deviations from Hardy-Weinberg equilibrium were observed. Comparative analysis results between our data and those from other Colombian and African population samples revealed significant differences, except with two Colombian Caribbean Coast sub-regions.  相似文献   
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An analytical method using solid-phase extraction (SPE) and high-performance liquid chromatography–mass spectrometry (LC–MS) has been developed and validated for the confirmation of Δ9-tetrahydrocannabinol (THC) in oral fluid samples. Oral fluid was extracted using Bond Elut LRC-Certify solid-phase extraction columns (10 cm3, 300 mg) and elution performed with n-hexane/ethyl acetate. Quantitation made use of the selected ion-recording mode (SIR) using the most abundant characteristic ion [THC + H+], m/z 315.31 and the fragment ion, m/z 193.13 for confirmation, and m/z 318.00 for the protonated internal standard, [d3-THC + H+]. The method proved to be precise for THC, in terms of both intra-day and inter-day analyses, with coefficients of variation less than 10%, and the calculated extraction efficiencies for THC ranged from 76 to 83%. Calibration standards spiked with THC between 2 and 100 ng/mL showed a linear relationship (r2 = 0.999). The method presented was applied to the oral fluid samples taken from the volunteers during the largest music event in Portugal, named Rock in Rio-Lisboa. Oral fluid was collected from 40 persons by expectoration and with Salivette®. In 55% of the samples obtained by expectorating, THC was detected with concentration ranges from 1033 to 6552 ng/mL and in 45% of cases THC was detected at concentrations between 51 and 937 ng/mL. However, using Salivette® collection, 26 of the 40 cases had an undetectable THC.  相似文献   
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Surfmen are thus called young daredevils who climb to the roof of suburban trains in Rio de Janeiro, Brazil and vie with each other in agility and prowess, some of them often falling on the railway tracks and being killed. The practice started as a need to hang on anything outside the crowded train and became a sport of sorts. Even though repressed by the railway authorities and punished by fines and imprisonment, the practice has been going on since the eighties and developed into a competition with rules, code of honour, grading of achievement. It became a means of improving self-esteem as well as securing leadership and social prestige by people who otherwise carry on lives devoid of any charm or ludic stimulus. A substitute behavior, it results from processes of cultural elaboration at work in the youth culture of our cities.  相似文献   
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The purpose of this study was to examine in a sample of 11,516 secondary school students the extent to which different behavioral, emotional and cognitive problems (a) reflected one or more underlying common factors; (b) actually cooccurred; and (c) were single problems. Principal Component Analyses were performed and percentagewise techniques were used. PCA demonstrated that one or more general syndromes could not by far account for all of the variance of the variables. The results suggest the existence of adolescent subgroups with divergent comorbidity patterns: those who primarily report one single symptom; those who report concurrent symptoms either exclusively in the category of behavioral problems or exclusively in the category of emotional and cognitive problems; and those who report concurrent symptoms in both categories. This distinction between different subgroups has important theoretical, diagnostic, and treatment implications.  相似文献   
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This article addresses the rise of corporate citizenship in the context of the changes in the nature of individual citizenship and the emergence of new, non‐territorial forms of national identity that are occurring in the current era of intensifying globalization. It also ponders the power of corporate citizens and the role they play in the prevailing global governance framework, as well as the extent to which they can behave responsibly and pursue sustainable development goals. More generally, the article discusses the limits to corporate social responsibility and the extent to which capitalism can be ‘caring’. The argument advanced is that, by virtue of their very nature, transnational corporations (TNCs) cannot become fully responsible and accountable citizens. Nonetheless, they can be induced to transform themselves in ways that may be compatible with socially and environmentally desirable objectives. Lastly, the article explores paths for action and, in particular, the potential of NGOs and anti‐globalization social movements to become civil regulators able to push for the introduction of binding rules and regulations and the construction a governance framework capable of restraining and harnessing the power of TNCs.  相似文献   
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This paper seeks to examine the extent to which left-wing forces are making a comeback in Latin America and to draw out the political implications of their political ascendancy. It argues that while left-of-centre parties have developed a persuasive critique of the failures of liberal democracy and economic neoliberalism in the region, there is as yet no conceptual clarity or distinct policy initiatives materialising from the left's promises of deepening democracy and implementing an alternative economic model. When in power, left-of-centre parties have followed a strategy of 'bending and moulding' existing political institutions and the free-market economic model rather than attempting radical political and economic reforms. This paper concludes that left-of-centre parties are right in accepting that there is little room in the region for an anti-systemic model and that instead the emphasis should be placed on making states, markets and democracy work better to secure development, address social demands and attack the root causes of discrimination and inequality. But leaving behind old certainties and adapting to the new political and economic environment has come at the cost of a loss of intellectual confidence, ideological clarity and weakened identities.  相似文献   
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