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1.
A new solid-phase extraction procedure for the determination of cocaine and benzoylecgonine in amniotic fluid, using high flow co-polymeric sorbents is reported. The recoveries of cocaine and benzoylecgonine within the range 0.1-1 mg/l were 95.7% and 50.3%, respectively. The use of high-flow sorbents allowed the easy extraction of amniotic fluid regardless of sample viscosity or physical nature. The use of these solid-phase columns provided many advantages over the more commonly used solvent extraction, including an increase in extraction speed and efficiency, reduced operator time, reduced solvent use and disposal volumes and exceptional extract quality. Further, the determination of amniotic fluid obtained from pregnant cocaine users may provide important information about handling of cocaine by the fetus at various gestational ages. The procedure was successfully applied to amniotic fluid from suspected cocaine abusers.  相似文献   
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American government in the twentieth century has been faced with a serious value conflict between the need for rational allocation of scarce resources through planning, and the need to be responsive to a diverse society. Two ideal types of planning correspond to these two values. Rational planning emphasizes the importance of the planner's expertise in achieving the "best" path to socially defined goals. Advocacy planning emphasizes the importance of responsiveness to group interests since all planning decisions are basically a matter of value choice. Citizen participation in planning often combines elements of these two models, embodying the value conflict in planning agency procedures. Health systems agencies are examined as a typical case of such planning. Their failure to build a constituency is viewed as a consequence of role conflict reduction strategies by representatives who did not know whether to play the planner or the advocate role, and how to play either.  相似文献   
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The effect of childhood trauma on later psychological adjustment   总被引:1,自引:0,他引:1  
This study examined whether adult attachment and cognitive distortion mediate the relationship between childhood trauma and psychological adjustment. The participants were 219 students (40 men and 117 women) enrolled in a university degree. Participants completed the Childhood Trauma Questionnaire, which assessed retrospective accounts of childhood trauma; the Relationships Scales Questionnaire, which measured two dimensions of adult attachment (model-of-self and model-of-other); the Cognitive Distortions Scale, which measured internal attributions and perceptions of controllability; and the Trauma Symptom Inventory, which assessed posttraumatic symptoms and was used in this study to measure psychological adjustment. Results supported the hypothesis that model-of-self and cognitive distortion are related constructs. The influence of model-of-self on psychological adjustment however was only via its effect on cognitive processes. In other words, a negative model-of-self influenced cognitive distortion, which in turn influenced the expression of symptoms in adults reporting a history of childhood trauma. The implications for therapy were considered.  相似文献   
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This article argues that the securitisation of an issue can involve not only negative, exclusionary and repressive extraordinary measures but also more positive, inclusionary and productive strategies of engagement. It also argues that such bifurcated strategies of security can evoke a spectrum of responses that sets limits on the process of securitisation. It examines these two arguments through the lens of the securitisation of development NGOs post-9/11. Development NGOs have become associated as a potential ‘second-order’ security issue related to the macro-securitisation of the War on Terror. After the launch of President Bush's War on Terror, US and allied governments shifted their approach to development NGOs from one of enthusiastically courting them as co-producers of development and security to an approach that cast greater suspicion on their activities. Aware that development NGOs still had a positive role to play in development and security, Western governments adopted a bifurcated strategy of containment and engagement towards development NGOs. State attempts to restrict development NGOs have evoked a spectrum of responses, ranging from ready compliance to outright resistance that has led to only partial success in securitising development NGOs.  相似文献   
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The need for accurate risk assessment of sexual offence recidivism has never been greater. It is widely accepted that actuarial risk instruments outperform clinical judgement and the literature has recently witnessed a surge of empirically derived actuarial measures. However, in spite of the increased levels of predictive accuracy, actuarial measures have been criticized as being unrepresentative, lacking specificity, and being heavily reliant on static risk factors without taking into account dynamic risk, psychological emotional states and treatment effects. Rather than offering a critique of the actuarial movement, this paper offers a summary of static and dynamic risk factors associated with sexual offence recidivism as identified from the literature. Implications of incorporating dynamic factors into risk assessments and actuarial measures are discussed.  相似文献   
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‘Sustainable development’ – as currently and politically correctly formulated – provides an inappropriate basis on which to frame a future-oriented UN agenda, and risks perpetuating patterns of assistance in which most UN organisations perform poorly and in the shadow of alternative and more able multilateral and bilateral sources. UN operations should take as their point of departure the comprehensive agenda outlined by the two world summits of 2000 and 2005. This agenda recognises the value-based UN as the only universal-membership organisation, which combines the concerns of satisfying human needs while ensuring security, human rights, justice and sound governance. The post-2015 agenda should not look only at development and environment but aspire to what a million global voices canvassed by the UN in ‘the world we want’ campaign are clamouring for.  相似文献   
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In this article I examine Onora O’Neill’s philosophical critique of human rights in the context of her appointment to the Chair of the Equality and Human Rights Commission and the recent political turn against human rights in the UK.  相似文献   
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The heterogeneity of domestic violent men has long been established. However, research has failed to examine this phenomenon among men committing the most severe form of domestic violence. This study aims to use a multidimensional approach to empirically construct a classification system of men who are incarcerated for the murder of their female partner based on the Holtzworth-Munroe and Stuart (1994) typology. Ninety men who had been convicted and imprisoned for the murder of their female partner or spouse in England were identified from two prison samples. A content dictionary defining offense and offender characteristics associated with two dimensions of psychopathology and criminality was developed. These variables were extracted from institutional records via content analysis and analyzed for thematic structure using multidimensional scaling procedures. The resultant framework classified 80% (n = 72) of the sample into three subgroups of men characterized by (a) low criminality/low psychopathology (15%), (b) moderate-high criminality/ high psychopathology (36%), and (c) high criminality/low-moderate psychopathology (49%). The latter two groups are akin to Holtzworth-Munroe and Stuart's (1994) generally violent/antisocial and dysphoric/borderline offender, respectively. The implications for intervention, developing consensus in research methodology across the field, and examining typologies of domestic violent men prospectively are discussed.  相似文献   
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