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The superheated debate over breast implants awakened a sleeping giant of an issue clouding "medical devices"--the government's clumsy nomenclature for any medical product that is not a drug, from breast implants and artificial hips to X-ray machines and surgical thread. Some 130 categories of high-risk devices are in use with little or no proof of safety, reliability or effectiveness. All appeared before 1976, the year that the Food and Drug Administration got the authority to regulate such products. Under activist chief David Kessler and with added clout from a 1990 law, the FDA plans to scrutinize the entire 130-item list. Five will get special attention starting early next year: saline-filled breast implants, inflatable penile implants, testicular implants, heart-bypass pumps and cranial stimulators. U.S. News has looked at all five devices, using FDA data obtained through the Freedom of Information Act. In-depth computer analysis suggested that penile implants deserve closer examination. Why is clear from the following report. 相似文献
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Tammy O Tengs Sajjad Ahmad Rebecca Moore Eric Gage 《Journal of policy analysis and management》2004,23(4):857-872
If manufacturing a safer cigarette is technically possible--an open question--then mandating that tobacco manufacturers improve the safety of cigarettes would likely have both positive and negative implications for the nation's health. On the one hand, removing toxins may reduce the incidence of smoking-related diseases and premature mortality in smokers. On the other hand, smokers might be less inclined to quit, those who have quit might resume the habit, and youth who have never smoked will have one less reason to avoid tobacco use. To assess the expected population health impacts of a legislative or regulatory mandate, we created the Tobacco Policy Model, a system dynamics computer simulation model. The model relies on secondary data and simulates the U.S. population over time spans as long as 50 years. Our simulation results reveal that even if requiring cigarettes to be safer makes smoking more attractive and increases tobacco use, a net gain in population health is still possible. 相似文献
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The relation between women’s histories of experiencing violence and current psychological health were examined. Locus of control, feelings of personal power, depressive symptomatology, self-esteem, and judgments of control over a contingently responsive computer display were investigated in groups of 21 abused women and 18 comparison women. Within the sample of abused women, relationships between severity of abuse and the psychological variables were also examined. The group of abused women had lower beliefs in self-efficacy, were more depressed, and had lower self-esteem than the comparison women. There were no differences found, however, between the two groups in perceptions of control on the computer task. Severity of physical abuse among the abused women was positively correlated with depression scores. Verbal abuse was found to contribute significantly to many of the between-group differences. Empirical evidence of the positive impact of transition house residence on the abused women’s mental health was also presented. The importance of future research into both the differential effects of verbal and physical abuse on women and the role of the transition house in empowering abused women were discussed. 相似文献
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Terrorism and relative justice 总被引:1,自引:0,他引:1
Mark Findlay 《Crime, Law and Social Change》2007,47(1):57-68
Terrorist violence and violent justice responses have much in common. While contextually dependant, both forms of violence
lay claim to contestred legitimacies. The relationships between terrorism and justice responses require both theoretical and
empirical examination if the prospects for controlling the violence they perpetrate is to be sharpened.
相似文献
Mark FindlayEmail: |
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Jackson SA Mammel MK Patel IR Mays T Albert TJ LeClerc JE Cebula TA 《Forensic science international》2007,168(2-3):183-199
Here, we describe a novel microarray-based approach for investigating the genomic diversity of Escherichia coli O157:H7 in a semi-high throughput manner using a high density, oligonucleotide-based microarray. This microarray, designed to detect polymorphisms at each of 60,000 base-pair (bp) positions within an E. coli genome, is composed of overlapping 29-mer oligonucleotides specific for 60 equally spaced, 1000-bp loci of the E. coli O157:H7 strain EDL933 chromosome. By use of a novel 12-well microarray that permitted the simultaneous investigation of 12 strains, the genomes of 44 individual isolates of E. coli O157:H7 were interrogated. These analyses revealed more than 150 single nucleotide polymorphisms (SNPs) and several deletions and amplifications in the test strains. Pyrosequencing was used to confirm the usefulness of the novel SNPs by determining their allelic frequency among a collection of diverse isolates of E. coli O157:H7. The tiling DNA microarray system would be useful for the tracking and identification of individual strains of E. coli O157:H7 needed for forensic investigations. 相似文献