Population genetic studies: is there an emerging legal obligation to share benefits?

It appears that large-scale population genetic studies are the necessary next step in genomics research. Such studies promise to provide correlative data to permit researchers to understand the etiology of a vast array of complex human diseases. Simultaneously, such studies are increasingly seen as yet another mechanism for the developed world to benefit at the expense of the developing world. In fact, a recent World Health Organization Report suggests that "without explicit attention at the international level, the initial technological fruits of genomics are likely to consist primarily of therapeutic and diagnostic applications for conditions affecting large populations in rich countries." (World Health Organization, Genomics and World Health, 2002). In developed and developing countries alike, there are concerns that the pharmaceutical industry stands to gain at the expense of the population(s) from which population genetic data are derived. In light of the current interest concerning ongoing population genetic studies and an increasing interest by many countries, Canada included, in embarking on large-scale population genetic research, it is appropriate to consider the concept of benefit-sharing as a potential mechanism to assuage these concerns. It is the author's position that by virtue of common law equitable principles and developing norms in international law, including the Human Genome Organization Statement on Benefit-Sharing, that there are principled legal and ethical reasons to compel the sharing of benefits that accrue from the commercialization of the resulting data. Using the United Nations Convention on Biological Diversity and the Bonn Guidelines as a model, I suggest that appropriate benefit-sharing mechanisms have been considered in the context of non-human biological materials and that these same mechanisms may be applicable in the context of international and intra-national population genetic studies.     

Responsible and responsive knowing in medical diagnosis: the medical gaze revisited

The medical gaze has long been privileged over the voice of the patient as the source of medical knowledge, in western societies. The ontology (that is, the very existence) of symptoms invisible to scientific observation will thus tend to be questioned by medical professionals. Yet any gaze, even the medical one, is refracted through the lenses both of social‐cultural stereotypes and of gender, and its seeings are shaped by these refractions. In this article, two family physicians and an epistemologist examine certain “unexplained” disorders, in a conversation informed by a feminist perspective: they bring a feminist point of view to bear on these issues. Medically unexplained disorders, which occur most frequently in women, are disabling conditions for which objectively observable symptoms and/or scientific causal explanations are not available. The approach taken in this article makes some of the assumptions underlying clinical knowledge more clearly visible: the authors' conversation situates diagnostic activity in medicine as a gendered, power‐infused social interaction within a cultural context where the gold standard of medical knowledge is very narrowly set. The participants propose responsible and responsive knowing as alternative strategies for knowing well. As they are presented here, these strategies incorporate an awareness of the inherent uncertainty of medical knowledge, raise questions about those to whom the knower is accountable, acknowledge the patient's experiences, and attend to the potentially oppressive effects of expert knowing.     

An Exploration of Religion and Education in the Life of Constance Maynard,Mistress of Westfield College

This article provides an overview of the motivation for digitising Maynard's writings, evaluates the benefits and challenges of reproducing and publishing archives, and considers the implications of greater digitisation. Maynard's writings reveal that she drew on her evangelical belief system as a means of protection and inspiration, and never overcame the concerns of early educationalists to maintain ‘decorum’ and ‘femininity’ in the management of the college. Published and unpublished sources are considered to review Maynard's decision to enter higher education, the inspiration for a Christian college for women, impact of contemporary arguments opposing education for women on Maynard and Westfield College, and Maynard's reaction to the development of a science faculty in the early twentieth century.     

第三方警务与保险——以市场为基准的犯罪预防案例研判（上）

本文试图探讨一种新的发展趋势。即以市场为基准展开的犯罪预防。保险公司是该种新型犯罪预防模式的代表机构。尽管保险的传统关注点在于犯罪或其他灾难发生后所遭受的损失，我们在此将揭示保险业从反应型犯罪管理模式向主动型管理模式的转变。该种趋势是更广义上的“去中心化警务”（decentralization of policing）的一部分，即警务从国家控制的管理机构向以社区和市场为基准的第三方的转移。新的意识形态支持这种转变，包括针对犯罪的保险统计理念的更新和对谨慎之人看法的转变。     

Campbell Collaboration systematic reviews and the Journal of Experimental Criminology: Reflections on the last 20 years

Journal of Experimental Criminology -