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1.
Tim Kalafut Simone Pugh Peter Gill Sarah Abbas Marie Semaan Issam Mansour James Curran Jo-Anne Bright Tacha Hicks Richard Wivell John Buckleton 《Journal of forensic sciences》2022,67(1):128-135
Semaan et al. (J Forensic Res, 2020, 11, 453) discuss a mock case “where eight different individuals [P1 through P8] could not be excluded in a mixed DNA analysis. Even though … expert DNA mixture analysis software was used.” Two of these are the true donors. The LRs reported are incorrect due to the incorrect entry of propositions into LRmix Studio. This forced the software to account for most of the alleles as drop-in, resulting in LRs 60–70 orders of magnitude larger than expected. P1, P2, P4, P5, and P8 can be manually excluded using peak heights. This has relevance when using LRmix which does not use peak heights. We extend the work using the same two reference genotypes who were the true contributors as Semaan et al. (J Forensic Res, 2020, 11, 453). We simulate three two-donor mixtures with peak heights using these two genotypes and analyze using STRmix?. For the simulated 1:1 mixture, one of the non-donors’ LRs supported him being a contributor when no conditioning was used. When considered in combination with any other potential donors (i.e., with conditioning), this non-donor was correctly eliminated. For the 3:1 mixture, all results correctly supported that the non-donors were not contributors. The low-template 4:1 mixture LRs with no conditioning showed support for all eight profiles as donors. However, the results from pair-wise conditioning showed that only the two ground truth donors had LRs supporting that they were contributors to the mixture. We recommend the use of peak heights and conditioning profiles, as this allows better sensitivity and specificity even when the persons share many alleles. 相似文献
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Richard Hornsey 《Women's history review》2019,28(1):111-138
In May 1935, the British manufacturer Boots launched ‘Number Seven’, a premium range of skin-care products sold via its nationwide network of chain-store chemists. Using material from the Boots Archive, this paper traces the early history of Number Seven to explore the changing meanings of middle-class cosmetics across the mid-twentieth century. Number Seven offered provincial and suburban women an explicitly modern form of facial beauty that married the logics of mass production to traditional moral aesthetics. Through the discourse of ‘loveliness’ and the careful management of in-store experience, it negotiated the prerogative connotations of colour cosmetics and the problematic influence of cinematic glamour. Yet by the mid-1950s, this construction had been superseded by a more situational understanding of beauty that was dependent on context and the appreciation of others. This fundamental shift in the normative aesthetics of public femininity had important implications for women on both sides of Boots’ toilet counters. 相似文献
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The #MeToo movement has done a great deal to address sexual abuse and violence. There is no doubt that justice may occur when the right person speaks out. However, what happens when the wrong people—that is, people of color, the working class women, and transgender people— speak out on the same issue? When these “wrong people” do speak out, they are discredited, marginalized, and silenced by being ignored. This Viewpoint essay addresses two populations that have been overlooked by the #MeToo movement: women of color and transgender people. The essay concludes with recommendations for how the movement can move forward given the criticisms around the absence of diversity and transparency. 相似文献
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We consider an election between two parties that nominate candidates for office. The parties are polarized along a traditional cleavage, but they are also internally divided along a second issue dimension. We introduce a threat of entry from Outsider candidates, who have the prominence and resources to bypass party elites. We consider when voters will turn to Outsiders, and identify the conditions under which Outsiders will enter the election through an established party's nomination process, as opposed to circumventing established parties via a third-party challenge. We further explore when the elites will fail to respond to the threat of Outsider candidates. Our framework highlights how established parties will be especially vulnerable to Outsider primary entry in periods of intense ideological polarization between the parties, and that this vulnerability is especially heightened for the majority party. 相似文献
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Richard Craven 《Journal of law and society》2020,47(1):29-59
The Public Services (Social Value) Act 2012 introduces a social value duty. It requires public authorities in England and Wales that are carrying out procurement activities to ‘consider’ how such activities might ‘improve … economic, social and environmental well-being’. This article analyses qualitative, empirical data on how the social value duty has been interpreted and applied across local government in England. Although only a weak legal duty, this law has made a notable impact on practice. The article explains the changes brought about in practice under the social value duty and seeks to understand why these changes have occurred. It does so by recognizing local government procurement markets, as well as local government organizations themselves, as strategic action fields. In these fields, there are competing visions for social value. It is through conversations between actors that a common meaning comes to be attached to the law. 相似文献