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正交试验法优选血康胶囊提取工艺
作者姓名:吴宗好  王晓华  郑琳
作者单位:[1]安徽省医学科学研究所,安徽合肥230061 [2]安徽中医学药学系
摘    要:目的:研究血康胶囊提取工艺。方法:采用正交试验法进行优选,以TLCS法测定人参皂苷Rg1的含量。结果:提取交数、乙醇浓度对人参皂苷Rg1提取率及干膏率有显性影响。结论:最佳提取工艺为500ml/L乙醇回汉提取2次,溶剂用量依次为6,5倍,提取时间为1.5,1.5h。

关 键 词:正交试验法  人参皂苷Rg1  干膏率  血康胶囊  提取工艺
修稿时间:2002/1/17 0:00:00

EXTRACTION PROCESS OF XUEKANG CAPSULE WITH ORTHOGONAL DESIGN
Abstract:Objective:To study the extraction process of Xuekang capsule. Method: The optimum extraction process was selected with the orthogonal design. The content of Ginenoside Rg 1 was determined by thin layer chromatography scanning. Results:The significant effects of extraction time and alcohol concentration on the extraction ratio of Ginenoside Rg 1 and ratio of dry extraction were observed. Conclusion: The optimum extraction process was as follows: with 500 ml/L alcohol for 2 times, with the solvent volume 6,5 folds amount and reflux for 1.5,1.5 hours in turn.
Keywords:Orthogonal design  Ginenoside Rg  1  Ratio of dry extraction  Xuekang capsule  Extraction process
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