| 油樟叶乙醇提取物抗炎活性的研究 |
| |
| 引用本文： | 魏琴,殷中琼,杜永华,周黎军,陶翠,贾仁勇.油樟叶乙醇提取物抗炎活性的研究[J].中国兽医科学,2011(8). |
| |
| 作者姓名： | 魏琴 殷中琼 杜永华 周黎军 陶翠 贾仁勇 |
| |
| 作者单位： | 宜宾学院发酵资源与应用四川省高校重点实验室;四川农业大学动物医学院;四川农业大学动物疫病与人类健康四川省重点实验室;宜宾学院生命科学与食品工程学院; |
| |
| 基金项目： | 教育部“长江学者和创新团队发展计划”创新团队项目(IRT0848); 四川省科技厅支撑项目(2009FZ0090); 宜宾市科技局项目(200903019) |
| |
| 摘 要： | 为探讨油樟叶乙醇提取物的抗炎活性,建立了用二甲苯诱导小鼠耳肿胀、醋酸诱导小鼠毛细血管通透性增加和角叉菜胶诱导大鼠足肿胀的模型,并测定了角叉菜胶所致大鼠足炎性渗出液中前列腺素E2、组胺和5-羟色胺的含量。结果表明,油樟叶乙醇提取物能显著抑制二甲苯所致的小鼠耳肿胀、醋酸诱导的小鼠毛细血管通透性增加和角叉菜胶所致的大鼠足肿胀,且呈剂量依赖性,并能显著降低角叉菜胶所致大鼠足炎性渗出液中前列腺素E2、组胺和5-羟色胺的含量。证实油樟叶乙醇提取物具有较好的抗炎活性。
|
| 关 键 词： | 油樟叶 乙醇提取物 抗炎活性 前列腺素 组胺 5-羟色胺 |
Anti-inflammatory activity of the ethanol extract from Cinnamomum longepaniculatum leaves |
| |
| WEI Qin,YIN Zhong-qiong,DU Yong-hua,ZHOU Li-jun,TAO Cui,JIA Ren-yong.Anti-inflammatory activity of the ethanol extract from Cinnamomum longepaniculatum leaves[J].Veterinary Science in China,2011(8). |
| |
| Authors: | WEI Qin YIN Zhong-qiong DU Yong-hua ZHOU Li-jun TAO Cui JIA Ren-yong |
| |
| Institution: | WEI Qin1,YIN Zhong-qiong3,4,DU Yong-hua1,2,ZHOU Li-jun1,TAO Cui3,JIA Ren-yong3,4 (1.Key Laboratory of Fermentation Resource and Application of Institutes of Higher Learning in Sichuan,Yibin 644007,China,2.College of Life Science and Engineering,Yibin University,3.College of Veterinary Medicine,Sichuan Agricultural University,Ya'an 625014,4.Key Laboratory of Animal Disease and Human Health of Sichuan Province,China) |
| |
| Abstract: | The anti-inflammatory activity of the ethanol extract from Cinnamomum longepaniculatum leaves was investigated with three experimental models including the dimethyl benzene-induced ear edema in mice,the acetic acid-induced vascular permeability in mice and the carrageenan-induced paw edema in rats.The prostaglandin E2(PGE2),histamine and 5-hydroxytryptamine(5-HT) in exudates of paw edema induced by carrageenan in rats were also detected for the evaluation of anti-inflammatory activity of the ethanol extract... |
| |
| Keywords: | Cinnamomum longepaniculatum leaves ethanol extract anti-inflammatory activity prostaglandin histamine 5-hydroxytryptamine |
| 本文献已被 CNKI 等数据库收录！ |
|
