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关于法庭科学DNA数据库若干问题的探讨
引用本文:葛建业,严江伟,Bruce Budowle.关于法庭科学DNA数据库若干问题的探讨[J].中国法医学杂志,2011,26(3):252-255.
作者姓名:葛建业  严江伟  Bruce Budowle
作者单位:1. Institute of Investigative Genetics,University of North Texas Health Science Center,Ft Worth;Department of Forensic and Investigative Genetics,University of North Texas Health Science Center,Ft Worth
2. 中国科学院北京基因组研究所,北京,100029
摘    要:本文论述常染色体STR基因座的选取和数量对数据库直接匹配、亲缘关系检索、失踪人员检索等数据库检索应用可能带来的影响,指出大容量DNA数据库在应用中可能出现的问题,并讨论应用数据库时需要考虑的群体和群体内差异,以及Y染色体和线粒体DNA对数据库检索的辅助作用。旨在为今后建设和完善具有中国特色的大容量DNA数据库提供参考和帮助。

关 键 词:法医物证学  DNA数据库  数据库匹配  亲缘关系检索  失踪人员检索  群体内差异

Issues on China forensic DNA database
GE Jianye,YAN Jiangwei,Bruce Budowle,Ranajit Chakraborty,Arthur Eisenberg.Issues on China forensic DNA database[J].Chinese Journal of Forensic Medicine,2011,26(3):252-255.
Authors:GE Jianye  YAN Jiangwei  Bruce Budowle  Ranajit Chakraborty  Arthur Eisenberg
Institution:GE Jianye1,2,YAN Jiangwei3,Bruce Budowle1,Ranajit Chakraborty1,Arthur Eisenberg1,2/1.Institute of Investigative Genetics,University of North Texas Health Science Center,Ft Worth,TX 76107,USA,2.Department of Forensic and Investigative Genetics,3.Beijing Institute of Genomics,Chinese Academy of Sciences,Beijing 100029,China
Abstract:This study investigates the effects of selection and number of selected autosomal STR loci for the forensic DNA database applications,such as database matching,familial searching,missing person identification,the effects of population substructure,and the Y chromosome and mitochondrial DNA as the supplemental tools to improve the searching results,and provides suggestions for further improving the China forensic DNA database.
Keywords:forensic biological evidence  DNA database  database matching  familial searching  missing person identification  population substructure  
本文献已被 CNKI 维普 万方数据 等数据库收录!
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