| 雏鸡感染马立克氏病强毒后抗氧化酶活性和丙二醛水平的变化 |
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| 引用本文： | 黄克和,陈万芳.雏鸡感染马立克氏病强毒后抗氧化酶活性和丙二醛水平的变化[J].中国兽医科学,1999(4). |
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| 作者姓名： | 黄克和 陈万芳 |
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| 作者单位： | 南京农业大学动物医学院 |
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| 摘 要： | 对１０日龄雏鸡人工感染马立克氏病强毒后，马立克氏病发病率为７８．０％，死亡率为７６．０％。在攻毒后２，４和６周，感染鸡血清中超氧化物歧化酶（ＳＯＤ）、血液中过氧化氢酶（ＣＡＴ）和谷胱甘肽过氧化物酶（ＧＳＨＰｘ）活性在总体上均显著低于健康对照组鸡（Ｐ＜０．０５），血清丙二醛水平极显著地高于健康对照组鸡（Ｐ＜０．０１）。结合对马立克氏病临床病例的研究结果认为，氧自由基介入了马立克氏病的发病过程。
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| 关 键 词： | 雏鸡 马立克氏病 抗氧化酶 丙二醛 |
Changes of the Activities of SOD, CAT and GSH Px and the Level of MDA in Chicks Infected
with Virulent Marek's Disease Virus |
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| Huang Kehe,Chen Wanfang.Changes of the Activities of SOD, CAT and GSH Px and the Level of MDA in Chicks Infected
with Virulent Marek's Disease Virus[J].Veterinary Science in China,1999(4). |
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| Authors: | Huang Kehe Chen Wanfang |
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| Abstract: | The
mobidity and mortality of Marek's disease (MD) in 10 day old chicks artificially infected with
virulent MD virus was 78% and 76% respectively. In the 2,4 and 6 weeks after challenge, the
activities of the serum superoxide dismutase (SOD), the blood catalase (CAT) and glutathione
peroxidase (GSH Px) in the affected chicks were generally much lower than those of the normal
control chicks (P<0.05), but the level of the serum MDA was significantly higher than that of the
normal control chicks (P<0.01). Combining with the previous researchs about field cases of MD.
it was suggested that oxygen free radicals were involved in the development of MD. |
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| Keywords: | Chick MD SOD CAT GSH Px MDA |
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