Use of sibling pairs to determine the familial searching efficiency of forensic databases |
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Authors: | Thomas M Reid Michael L Baird John P Reid Susannie C Lee Richard F Lee |
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Institution: | aDNA Diagnostics Center, One DDC Way, Fairfield, OH 45014, USA |
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Abstract: | Pairs of individuals tested at the 13 CODIS core STR loci to determine sibship were used as a source of familial data that was seeded into a larger data set of 12,000 plus DNA profiles simulating a CODIS-like offender database. To determine whether known sibs could be found in the larger database two methods were used: degree of allele sharing and a kinship matching approach. The allele sharing method detected 62 of 109 of the known sib pairs (57%) while kinship matching detected 90 of the sib pairs (83%). Although kinship matching was the more efficient method of the two, the number of false positives generated prior to finding a true match was inversely related to the likelihood of sibship suggesting that many true siblings would not be easily found in a large forensic database via familial searching techniques. |
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Keywords: | STR loci Familial Database Searching Kinship |
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