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创缘周围血管生成在皮肤损伤时间推断中的应用
引用本文:陈志明,卢英强,宣兆艳,刘东辉,王利君.创缘周围血管生成在皮肤损伤时间推断中的应用[J].中国法医学杂志,2006,21(3):163-165.
作者姓名:陈志明  卢英强  宣兆艳  刘东辉  王利君
作者单位:1. 吉林大学基础医学院法医教研室,吉林,长春,130021
2. 长春市公安局,吉林,长春,130021
摘    要:皮肤损伤时间推断一直以来都是法医病理学者所需解决的重要问题,免疫组织化学技术具有方便、敏感的特性,它的应用大大提高了皮肤损伤时间推断研究的发展。然而,有效指标的缺乏却限制了免疫组织化学技术的应用。血管生成在皮肤损伤愈合过程中发挥着非常重要的作用,因此,血管生成相关因子可能在皮肤损伤时间推断方面具有重要价值。

关 键 词:法医病理学  皮肤损伤时间推断  血管生成
文章编号:1001-5728(2006)03-0163-03
修稿时间:2005年5月31日

Application of micro-vascularity incurred during skin wound repair to wound age determination
CHEN Zhi-ming,LU Ying-qiang,XUAN Zhao-yan,et al..Application of micro-vascularity incurred during skin wound repair to wound age determination[J].Chinese Journal of Forensic Medicine,2006,21(3):163-165.
Authors:CHEN Zhi-ming  LU Ying-qiang  XUAN Zhao-yan  
Institution:CHEN Zhi-ming,LU Ying-qiang,XUAN Zhao-yan,et al. Forensic Department of Basic Medical College in Jilin University,Jilin 130021,China
Abstract:Determination of wound age has long been one of the most important missions of the forensic pathologist in practice.During the last several decades,the use of immunohistochemical technique,which is considered as a convenient and sensitive method,has greatly improved the potential to estimate wound age.However,the lack of effective immunohistochemical markers has greatly limited the application of the technique.Angiogenesis plays a critical role during wound healing process.Therefore,some biological factors involved in angiogenesis may be possibly useful markers for wound age determination.
Keywords:Forensic pathology  skin wound age determination  Angiogenesis
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