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| 中国西北地区新城疫病毒分离株基因型与抗原性的关系 | |
| 引用本文： | 梁荣,曹殿军,陈杰,李健强,段明星.中国西北地区新城疫病毒分离株基因型与抗原性的关系[J].中国兽医科学,2001,31(7):5-8. |
| 作者姓名： | 梁荣 曹殿军 陈杰 李健强 段明星 |
| 作者单位： | 1. 清华大学生物科学与技术系,北京,100084;中国农业科学院哈尔滨兽医研究所,兽医生物技术国家重点实验室,黑龙江,哈尔滨,150004 2. 中国农业科学院哈尔滨兽医研究所,兽医生物技术国家重点实验室,黑龙江,哈尔滨,150004 3. 西北农林科技大学,动物科学与动物医学学院,陕西,杨凌,712100 4. 清华大学生物科学与技术系,北京,100084 |
| 摘 要： | 从我国西北地区分离到10株新城疫病毒(NDV),在蚀斑纯化、致病力和基因型鉴定的基础上,以LaSota、F48E9株免疫血清与分离毒株进行中和试验和交叉血凝抑制试验(HI).结果表明,弱毒株LaSota的免疫血清对分离毒株具有一定的保护力,但随毒株的不同有很大差异,对分离毒的中和指数远远低于强毒株F48E9免疫血清的中和指数.结合基因型鉴定结果,认为这种差别很可能是造成LaSota系疫苗免疫失败的原因之一. |
| 关 键 词： | 新城疫病毒 基因型 中和指数 |
| 文章编号： | 1000-6419(2001)07-0005-04 |
| 修稿时间： | 2001年3月13日 |
The relation of genotype and antigency of Newcastle disease virus strains isolated from northwestern China |
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| LIANG Rong ,CAO Dian jun ,CHEN Jie ,LI Jian qiang ,DUAN Ming xing.The relation of genotype and antigency of Newcastle disease virus strains isolated from northwestern China[J].Veterinary Science in China,2001,31(7):5-8. | |
| Authors: | LIANG Rong CAO Dian jun CHEN Jie LI Jian qiang DUAN Ming xing |
| Institution: | LIANG Rong 1,2,CAO Dian jun 2,CHEN Jie 3,LI Jian qiang 3,DUAN Ming xing 1 |
| Abstract: | NDV strains were isolated from northwestern China. After plague cloned, the virulence and genotype were detected. Neutralization test and cross HI test indicated that Anti LaSota strain sera could neutralize all strains, but there are much difference between different strains. Neutralization index of isolated vrius was much lower than that of F 48 E 9 strains sera. Combined the resultes of the identifying of their genotype, we thought that this kind of difference might be one of the reaoson that LaSota strain immunication defeated.ed .NeutralizationtestandcrossHItestindic |
| Keywords: | Newcastle disease virus genotype Neutralization index |
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