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Study of 16 X-STRs in a prostate cancer population sample (preliminary results) |
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| Authors: | R Carvalho MF Pinheiro R Medeiros |
| Institution: | a Universidade do Porto, Portugal b Instituto Nacional de Medicina Legal, Delegação do Porto, Portugal c Universidade Fernando Pessoa, Porto, Portugal d Instituto de Ciências Biomédicas de “Abel Salazar”, Porto, Portugal e Grupo de Oncologia Molecular, I.P.O. Porto, Portugal |
| Abstract: | Prostate cancer, like numerous other cancers is a result of genetic alterations that accumulate during disease progression. Study of short tandem repeats (STRs) have already demonstrated that this type of polymorphism could provide a mean to rapidly scan genomes at known or unknown predisposing loci for some diseases. In this study, DNA samples of 282 unrelated males with prostate cancer and 101 apparently healthy and unrelated males were analysed with Argus X-8 (Biotype®) and 77 with a new X-Decaplex used in a collaborative study of GEP-ISFG. |
| Keywords: | X-STR Prostate cancer North of Portugal |
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