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法医学相关SNP的分类
引用本文:景晶晶,李潭.法医学相关SNP的分类[J].辽宁警专学报,2009(6):61-63.
作者姓名:景晶晶  李潭
作者单位:中国医科大学临床医学七年制 91期3班,辽宁 沈阳,110001
摘    要:法医学的样本通常已经高度腐败降解或是只残留很少的DNA模板,因此,需要改变原有的遗传标记和分析的方法以便更好地应用于日常工作和案件。单核苷酸多态性(SNP)为法DNA分析提供了可能。SNP标记将在具有挑战性的法医学样本分析中发挥重要作用.如分析过度降解的检材.提高对于身份不明和走失者亲缘关系鉴定的能力.或在某些案件中提供嫌疑人的线索。SNP的法医学应用可分为四个方面:身份鉴定SNP、系谱推断SNP、始祖推断SNP和表型推断SNP。

关 键 词:SNP  分类  法医学应用

Relevant SNP Classes in Forensics
JING Jingjing,LI Tan.Relevant SNP Classes in Forensics[J].Journal of Liaoning Police Academy,2009(6):61-63.
Authors:JING Jingjing  LI Tan
Institution:1K3B, Seven-year-system of Clinical Medicine, China Medical University, Shenyang Liaoning 110001, China)
Abstract:Forensic samples that contain too little template DNA or are too degraded, and require alternate genetic marker analyses or approaches to what is currently used for routine casework. Single nucleotide polymorphisms (SNP) offer promise to support forensic DNA analyses. The SNP markers will serve an important rote in analyzing challenging forensic samples, such as those that are quite degraded, for augmenting the power of kinship analyses and family reconstructions for missing persons and unidentified human remains, as well as for providing investigative lead value in some cases without a suspect. The SNP for forensic analyses can be divided into four categories: identity-testing SNP; lineage informative SNP; ancestry informative SNP; and phenotype informative SNP.
Keywords:SNP
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