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肌成纤维细胞的研究进展及其法医学应用
引用本文:于天水,凌跃,官大威.肌成纤维细胞的研究进展及其法医学应用[J].法医学杂志,2013(2):140-143.
作者姓名:于天水  凌跃  官大威
作者单位:[1]中国政法大学证据科学教育部重点实验室,北京100040 [2]中国医科大学法医学院,辽宁沈阳110001 [3]南通市公安局崇川分局,江苏南通226006
基金项目:基金项目:国家自然科学基金青年科学基金资助项目(81202383);教育部高等学校博士学科点专项科研基金资助项目(200801590020)
摘    要:肌成纤维细胞(myofibroblast)同时具有平滑肌细胞和成纤维细胞双重特性,在组织损伤修复中,肌成纤维细胞参与纤维化级联反应中纤维形成和细胞外基质重塑两个阶段。本文综述了肌成纤维细胞形态学特征和生物学特性的研究进展及其在皮肤损伤时间推断中的作用,以期为法医学研究提供参考。

关 键 词:法医病理学  肌成纤维细胞  综述[文献类型]  损伤时间推断

Progress in Myofibroblast and Its Application in Forensic Medicine
YU Tian-shui,LING Yue,GUAN Da-wei.Progress in Myofibroblast and Its Application in Forensic Medicine[J].Journal of Forensic Medicine,2013(2):140-143.
Authors:YU Tian-shui  LING Yue  GUAN Da-wei
Institution:1. Key Laboratory of Evidence Science, Ministry of Education, China University of Political Science and Law, Beijing 100040, China; 2. School of Forensic Medicine, China Medical University, Shenyang 110001, China; 3. Chongchuan Branch of Nantong Public Security Bureau, Nantong 226006, China)
Abstract:The myofibroblasts have dual characteristics of smooth muscle cells and fibroblasts. In repair- ing tissular wound, myofibroblasts are involved in fibrogenesis and remodeling the extracellular matrix of the fibrotic cascades reaction. The review describes the morphological characteristics and biological be- haviors of myofibroblasts and the application of skin wound age determination, which may provide refer- ence for research in forensic medicine.
Keywords:forensic pathology  myofibroblast  review [publication type]  wound age determination
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