Abstract: | Objective:To study the effects of total glucosides on Radix paeonieae rubra of coagulation and thrombus formation.Method:Total glucosides of Radix paeonieae rubra were used in ig.At dosage of 50,100and 200mg/kg,observed the effects on blood coagulation time of mice and rats,the respiratory distress due to pulmonary thrombosis in mice induced by ADP Na and the thrombus formation of rats by electro irritation.Result:The glucosides on Radix paeonieae rubra can markedly prolong blood coagulation time of mice and rats,relieved respiratory distress due to pulmonary thrombosis in mice induced by ADP Na,inhibit the thrombosis formatin of rats by electro irritation.Conclusion:The anticoagulation and anti thrombosis effects of glucosides on Radix paeonieae rubra is powerful. |