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| 大鼠心肌早期缺血内皮素的表达 | |
| 引用本文： | Ma M,Xu X,Luo B,Wu X,Zhu J. 大鼠心肌早期缺血内皮素的表达[J]. 法医学杂志, 2000, 16(3): 141-142 |
| 作者姓名： | Ma M Xu X Luo B Wu X Zhu J |
| 作者单位： | 1. 中国人民公安大学侦察系法医学教研室,北京,100038 2. 汕头大学医学院法医学教研室,广东,515031 3. 中山医科大学法医病理学教研室,广东广州,510089 |
| 基金项目： | 国家自然科学基金资助项目 !(No 39700167) |
| 摘 要： | 为探讨心肌缺血后内皮素在心肌组织内表达的变化。用免疫组化SABC法研究内皮素的表达情况。结果发现缺血60min后 ,缺血区心肌细胞呈局灶性阳性 ;缺血120min后 ,血管平滑肌、内皮细胞及心肌细胞浆均呈阳性着色。对照和缺血30min组心肌组织未见有阳性反应。上述各组HE染色未见明显病理改变。 |
| 关 键 词： | 早期心肌缺血 内皮素 免疫组化 SABC法 |
Expression of ET of early ischemic myocardium in rats |
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| Ma M,Xu X,Luo B,Wu X,Zhu J. Expression of ET of early ischemic myocardium in rats[J]. Journal of Forensic Medicine, 2000, 16(3): 141-142 | |
| Authors: | Ma M Xu X Luo B Wu X Zhu J |
| Affiliation: | Sun Yat-sen University of Medical Sciences, GuangZhou 510089, PRC. |
| Abstract: | To study the expression of ET of early ischemic myocardium, we designed a model of early myocardial ischemia (EMI) in rats The study was conducted with SABC method and HE staining Cardiac myocytes of ischemia showed a little ET-positive at 60-min Cardiac myocytes, endothelium and smooth muscle of vessel showed ET-positive staining in the area of EMI after 120-min Staining was negative for Ischemia myocardium at 30-min and for the control group No change was seen with HE staining in all groups The data indicates that ET-SABC method may reveal the injury of myocardial ischemia 60-min and longer and may provide a new marker to diagnose EMI in forensic pathology |
| Keywords: | Early myocardial ischemia ET ABC method(Original article on page 141) |
| 本文献已被 CNKI 维普 万方数据 PubMed 等数据库收录！ | |