| 广东汉族人群D7S809的基因频率及其在亲子鉴定中的应用 |
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| 作者姓名： | Lu D Liu QL Wu XR |
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| 作者单位： | 中山医科大学法医学系, |
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| 摘 要： | 利用PCR和聚丙烯酰胺凝胶电泳分型技术，调查了以四核苷酸为重复单位的位点D7S809在广东人群的群体资料。在190个被调查的个体中，共发现14个等位基因和50种基因型。经计算杂合率、个人识别率和非父排除率分别为0.8613、0.9645和0.7184，基因型分布符合Hardy-Weinberg平衡。D7S809位点已成功地应用于100例亲权鉴定案中。D7S809是一个高度多态性、稳定、易于分型的位点，在法医学上极有应用价值。
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| 关 键 词： | 微卫星 D7S809 群体数据 亲权鉴定 广东人 |
| 文章编号： | 1004-5619（2001）01-0017-02 |
| 修稿时间： | 1999年9月15日 |
Cantonese population data of the tetranucleotide repeat locus D7S809 and its application in paternity test |
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| Lu D,Liu QL,Wu XR.Cantonese population data of the tetranucleotide repeat locus D7S809 and its application in paternity test[J].Journal of Forensic Medicine,2001,17(1):17-18. |
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| Authors: | Lu D Liu Q L Wu X R |
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| Institution: | Faculty of Forensic Medicine, Sun Yat-sen University of Medical Sciences, Guangzhou, Guangdong 510089. |
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| Abstract: | The tetranucleotide repeat locus D7S809 was investigated in Cantonese population by polymerase chain reaction (PCR) amplification, subsequent polyacryramide gel electrophoresis and silver staining. 14 alleles and 50 genotypes were detected in 190 sample individuals. All alleles differed in size by 4bp repeat. No interalleles were found. The heterozygosity, power of discrimination and chance of non-paternal exclusion were 0.8613, 0.9645 and 0.7184 respectively. No significant deviations from Hardy-Weinberg equilibrium were found. The D7S809 was a highly polymorphic, stable and accurate type locus and had been successfully applied to 100 paternity test cases. |
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| Keywords: | D7S809 |
| 本文献已被 CNKI 维普 万方数据 PubMed 等数据库收录！ |
