| 龙葵素中毒及检测的研究进展 |
| |
| 引用本文： | 董晓茹,沈敏,刘伟.龙葵素中毒及检测的研究进展[J].中国司法鉴定,2013(2):35-41. |
| |
| 作者姓名： | 董晓茹 沈敏 刘伟 |
| |
| 作者单位： | 1. 司法部司法鉴定科学技术研究所上海市法医学重点实验室,上海200063;苏州大学材料与化学化工学部,江苏苏州215123
2. 司法部司法鉴定科学技术研究所上海市法医学重点实验室,上海,200063 |
| |
| 基金项目： | 上海市科委资助项目，上海市法医学重点实验室 |
| |
| 摘 要： | 龙葵素（Solanen）是存在于茄科植物马铃薯中的有毒甾体类糖苷生物碱。成熟的马铃薯中,龙葵素的含量一般为7~10mg/100 g,食用是安全的。当马铃薯由于贮存不当而变绿或发芽时,会产生大量的龙葵素,当龙葵素的含量超过20mg/100 g时,人服用后可能会导致中毒甚至死亡,相关中毒案件时有报道。结合近年来关于马铃薯中有毒成分龙葵素的研究作一综述,总结了龙葵素毒理学、药理学、药代动力学及检测方法,为法医毒理学工作者提供参考。
|
| 关 键 词： | 龙葵素 马铃薯糖苷生物碱 中毒 检测 |
Advances in Research on Solanen Poisoning and Analysis |
| |
| DONG Xiao-ru,SHEN Min,LIU Wei.Advances in Research on Solanen Poisoning and Analysis[J].Chinese Journal of Forensic Sciences,2013(2):35-41. |
| |
| Authors: | DONG Xiao-ru SHEN Min LIU Wei |
| |
| Institution: | 1.Shanghai Key Laboratory of Forensic Medicine, Institute of Forensic Science, Ministry of Justice, Shanghai 200063, China; 2. College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, China) |
| |
| Abstract: | Solanen, toxic steroidal glycoalkaloid, exists in solanaceous plants such as potato plant.Mature potatos containing 7-10 mg solanen/100g potato is safe for human consumption. Solanen can be rapidly stimulated when potato turns green and sprouted by improper storage. Solanen has been estimated to he toxic in human at doses greater than 20 mg/100g potato. This paper summarizes the current researches on solanen in potato, the toxicology, pharmacology, pharmacokineties and determina-tion of solanen, provides the reference for forensic toxicology workers. |
| |
| Keywords: | solanen potato glycoalkaloids poisoning detection |
| 本文献已被 维普 万方数据 等数据库收录！ |
|
