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| 肢体挤压伤大鼠早期心电图及血清cTnI的变化 | |
| 引用本文： | Chen YC,Liu SP,Guo W. 肢体挤压伤大鼠早期心电图及血清cTnI的变化[J]. 法医学杂志, 2002, 18(2): 76-77 |
| 作者姓名： | Chen YC Liu SP Guo W |
| 作者单位： | 中山医科大学法医病理学教研室,广东广州,510080 |
| 摘 要： | 目的观察挤压伤大鼠早期心电图的改变,并检测血清心肌肌钙蛋白I(cTnI)的变化。方法复制挤压伤大鼠动物模型,标准Ⅱ导联记录心电图变化,化学发光法检测血清cTnI水平。结果挤压伤后心电图ST段明显抬高,并持续24h,伤后6h血清cTnI则显著升高,并持续24h以上。结论肢体挤压伤早期存在心肌细胞的损伤。 |
| 关 键 词： | 挤压损伤 心肌肌钙蛋白 心电图 |
| 文章编号： | 1004-5619(2002)02-0076-02 |
| 修稿时间： | 2001-07-12 |
The changes of electrocardiogram and serum cardiac troponin I at the early stage of crush injury in rats |
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| Chen Yu-chuan,Liu Shui-ping,Guo Wei. The changes of electrocardiogram and serum cardiac troponin I at the early stage of crush injury in rats[J]. Journal of Forensic Medicine, 2002, 18(2): 76-77 | |
| Authors: | Chen Yu-chuan Liu Shui-ping Guo Wei |
| Affiliation: | Department of Forensic Pathology, Sun Yat-sen University of Medical Sciences, Guangzhou 510080. |
| Abstract: | OBJECTIVE: To observe the changes of electrocardiogram and serum cardiac troponin I at the early stage of severe crush injury in rats. METHODS: Crush injury was produced in Sprague-Dawley rats. The changes of electrocardiogram were recorded with the standard II, the serum levels of cardiac troponin I were studied by automated chemiluminescence assay. RESULTS: The ST segment elevated considerably after crush injury and lasted 24 h, the levels of serum cTnI were much higher than those of the control groupes after 6 h of injury. CONCLUSION: Cardiomyocyte injury was induced in the early phase of crush injury. |
| Keywords: | crush injury cardiac troponin electrocardiogram. |
| 本文献已被 CNKI 维普 万方数据 PubMed 等数据库收录！ | |