Properties of novel and widely studied Y-STR loci in three South African populations |
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Authors: | Leat Neil Ehrenreich Liezle Benjeddou Mongi Cloete Kevin Davison Sean |
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Institution: | Biotechnology Department, University of the Western Cape, Private Bag X17, Bellville, 7535 Cape Town, South Africa. nleat@uwc.ac.za |
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Abstract: | The objective of the present study was to examine the properties of a set of single-copy Y-STR loci to assess their suitability for forensic casework in three South African populations. Three criteria were used to select markers for assessment. Firstly, the single-copy markers of the minimal haplotype were selected based on their established use in forensic studies. Secondly, 8 markers were selected on the basis of high gene diversity values reported for several population studies, and thirdly 19 markers were chosen from a survey of Y-chromosome sequence with selections made primarily on the basis of the number of repeated elements present. Samples were typed from 101 English-speaking Caucasians, 88 Xhosa individuals and 77 Asian Indians. Gene diversity values, the number of alleles identified and the average stutter was determined for each locus. |
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