| 青壮年猝死综合征心肌细胞内纤维连接蛋白免疫组化观察初探 |
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| 引用本文： | 胡丙杰,陈玉川.青壮年猝死综合征心肌细胞内纤维连接蛋白免疫组化观察初探[J].法医学杂志,1996,12(1):15-16. |
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| 作者姓名： | 胡丙杰 陈玉川 |
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| 作者单位： | 中山医科大学法医学系 |
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| 摘 要： | 本文应用免疫组化ＬＳＡＢ法首次对５例青壮年碎死综合征和１１例非心性死亡对照组进行心肌细胞内纤维连接蛋白的研究。发现青壮年猝死综合征５例中有３例心肌细胞内纤维连接蛋白阳性。１１例非心性死、对照组心肌细胞内纤维连接蛋白均呈阴性。说明上述３例青壮年猝死综合征的心肌细胞已发生不可逆损伤，实属早期心肌梗死。该研究为青壮年猝死综合征的死因研究提供了一个新的方向和手段。
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| 关 键 词： | 青壮年猝死综合征 纤维连接蛋白 免疫组化 LSAB法 |
Immunohistochemical Demonstration of Fibronectin in Myocytes of Sudden Manhood Death Syndrome |
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| Ha Bingjie, Chen Yachuan,Zhu Jinzhen.Immunohistochemical Demonstration of Fibronectin in Myocytes of Sudden Manhood Death Syndrome[J].Journal of Forensic Medicine,1996,12(1):15-16. |
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| Authors: | Ha Bingjie Chen Yachuan Zhu Jinzhen |
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| Abstract: | Immunohistochemical study of fibronectin (FN) was performed on the hearts of o cases of sudden manhood death syndromc (SMDS) and 11 cases of noncardiac death controls with LSAB-method. The results showed that FN was positive in cardiomyocytes of 3 cases of SMDS, but negative in all 11 non-cardiac death controls.It indicated that irreversible cell injury bad taken place in the 3 cases of SMDS,which.should be diagnosed as early myocardial infarction.This experiment provides a new approach for studying the causes of death of SMDS. |
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| Keywords: | sudden manhood death syndrome fibronectin immunohistochemistry LSAB-method |
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