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| 中国鄂温克族DXS7423，DXS7424，DXS7132，DXS7133，DXS6804位点多态性的研究 | |
| 作者姓名： | Gu SZ Tong ME Li XZ |
| 作者单位： | 1. 西安交通大学教育部环境与疾病相关基因重点实验室,陕西,西安,710061 2. 内蒙古高级人民法院司法鉴定技术处,内蒙古,呼和浩特,010000 3. 内蒙古人民检察院技术处,内蒙古,呼和浩特,010000 |
| 摘 要： | 目的以无关个体为研究对象,研究鄂温克族人群X染色体5个STR位点的遗传多态性,建立群体遗传数据库。方法用聚合酶链反应(PCR)、变性聚丙烯凝胶电泳和银染的方法,检测98名中国鄂温克族DXS7423,DXS7424,DXS7132,DXS7133,DXS6804位点的重复序列长度的变化。结果5个STR位点在鄂温克族群体均具有遗传多态性,χ2检验表明多态性分布符合Hardy-Weinberg平衡定律。结论中国鄂温克族X染色体5个STR基因座群体遗传数据资料,可用于法庭科学个体识别、亲子鉴定及其他人类学研究。 |
| 关 键 词： | X染色体 短串联重复序列(STR) 遗传多态性 中国鄂温克族群体 |
| 文章编号： | 1004-5619(2005)03-0192-03 |
| 修稿时间： | 2004年10月25 |
Genetic polymorphism of DXS7423, DXS7424, DXS7132, DXS7133, DXS6804 loci on X-chromosome in Ewenke population |
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| Gu SZ,Tong ME,Li XZ.Genetic polymorphism of DXS7423, DXS7424, DXS7132, DXS7133, DXS6804 loci on X-chromosome in Ewenke population[J].Journal of Forensic Medicine,2005,21(3):192-194. | |
| Authors: | Gu Shan-zhi Tong Mu-er Li Xiao-zhong |
| Institution: | The key Laboratory of Environment and Genes Related to Diseases of Ministry of Education, Xi'an Jiaotong University, Xi'an 710061, China. |
| Abstract: | Objective To study the genetic polymorphism of five STR loci on X- chromosome in 98Ewenke population of China and establish the related genetic database. Methods The sequence variationof DXS7423,DXS7424,DXS7132,DXS7133,DXS6804 loci on X- chromosome were analyzed by PCR fol-lowing PAG electrophoresis and silver staining. Results The genetic data of the 5 X- chromosome STRs inEwenke ethnic group of China is in accordance with Hard- Weinberg equilibrium. Conclusion Five X- STRloci could be used in forensic identification and population genetic research. |
| Keywords: | X-chromosome short tandem repeat(STR) genetic polymorphism Ewenke population |
| 本文献已被 CNKI 维普 万方数据 PubMed 等数据库收录！ | |