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Genetic analysis of 15 STR loci in the population of Zhejiang Province (Southeast China)
Authors:Yuning Zhu   Shiming Lu   Zhenwei Xie   Yan Chen  Jianfei You
Affiliation:aWomen's Hospital, School of Medicine, Zhejiang University, Xueshi Road 2#, Hangzhou 310006, Zhejiang, China
Abstract:Fifteen autosomal STR loci were analyzed from a population sample of 598 unrelated individuals residing in Zhejiang Province. We report allele frequencies distribution and statistical parameters for all 15 STR loci, D8S1179, D21S11, D7S820, CSF1PO, D3S1358, THO1, D13S317, D16S539, D2S1338, D19S433, VWA, TPOX, D18S51, D5S818 and FGA. Allele frequencies, the observed heterozygosity (Ho), the polymorphic information content (PIC), and the probability of paternity exclusion (PE) were calculated. All loci were in accordance with Hardy–Weinberg equilibrium (P > 0.05). Our studied population data were compared with the previously published population data of other ethnic groups or areas in China. Our results of present study were valuable for human identification and paternity tests in Zhejiang Province.
Keywords:Forensic science   Population genetics   Short tandem repeats (STRs)   Zhejiang Province
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