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Genetic analysis of 15 STR loci on Chinese Tibetan in Qinghai Province
Authors:Yan Jiangwei  Shen Chunmei  Li Yuanzhe  Yu Xiaoguang  Xiong Xin  Mu Haofang  Huang Yanqing  Deng Yajun  Yu Jun
Institution:Beijing Genomics Institute, Chinese Academy of Sciences, Beijing 101300, PR China.
Abstract:We report allele frequencies and statistical parameters of 15 short tandem repeats (STR) loci (D8S1179, D21S11, D7S820, CSF1PO, D3S1358, TH01, D13S317, D16S539, D2S1338, D19S433, vWA, TPOX, D18S51, D5S818 and FGA) determined in 850 unrelated individuals of Chinese Tibetan, an ethnic group residing in Qinghai Province, China. We observed 155 alleles with allele frequencies ranging from 0.0006 to 0.5682. The distribution of these observed genotypes were not significantly different from the expected distribution according to Hardy-Weinberg equilibrium. The forensic parameters from the data showed high values. In conclusion, the 15 STR loci are useful for forensic analysis, paternity tests for Tibetans in the region, and population genetic studies.
Keywords:Short tandem repeat (STR)  AmpFLSTR Identifiler™  Population data  Tibetan
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