Distinguishing antemortem from postmortem injuries by LTB4 quantification |
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| Institution: | 1. Department of Neuroscience, Imaging and Clinical Sciences, “G.d’Annunzio” University, Via dei Vestini 31, 66100 Chieti, Italy;2. RiSSC – Research Centre on Security and Crime, Via Casoni 2, 36040 Torri di Quartesolo, Vicenza, Italy;1. Department of Medical and Surgical Sciences DIMEC, University of Bologna, Italy;2. Section of Legal Medicine, Department of Excellence SBSP, Università Politecnica delle Marche of Ancona, Italy;1. Biogeochemistry Research Centre, SoGEES, Plymouth University, Plymouth, Devon PL4 8AA, UK;2. Energy & Geoscience Institute, 423 Wakara Way Suite 300, Salt Lake City, UT 84108, USA;3. Department of Environmental Science, Mount Royal University, 4825 Mount Royal Gate SW, Calgary, Alberta T3E 6K6, Canada;4. Environment and Sustainability Institute, University of Exeter, Penryn Campus, Penryn, Cornwall TR10 9EZ, UK;5. Department of Civil and Environmental Engineering, University of Strathclyde, Glasgow G1 1XQ, UK;1. Department of Neurosurgery, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Inkosi Albert Luthuli Central Hospital, KwaZulu-Natal, South Africa;2. Trauma Unit and Trauma Intensive Care, Inkosi Albert Luthuli Central Hospital, South Africa;3. Department of Surgery, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, South Africa;1. Universidade Estadual de Santa Cruz, Programa de pós-graduação em Zoologia, Ilhéus, BA, Brazil;2. FMT-Faculdade Madre Thais, Ilhéus, BA, Brazil;3. Universidade Estadual de Santa Cruz, Departamento de Biologia, Ilhéus, BA, Brazil |
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| Abstract: | Leukotriene B4 (LTB4) in skin samples from seven forensic cases was detected by HPLC to distinguish their antemortem or postmortem origin. In total, there were thirteen antemortem and seven postmortem specimens. The results showed that LTB4 was found in all antemortem wound specimens which were either fresh, or refrigerated or fixed in formalin for less than 10 days. In contrast, LTB4 could not be detected in postmortem wound specimens. These results suggested that detecting the content of LTB4 is a useful method for distinguishing antemortem from postmortem injuries. |
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