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通督调神针刺结合化瘀通络灸治疗痰瘀阻络型后循环缺血性眩晕临床观察
作者姓名:张国庆  张 玲  朱玲玲  张君宇  童婷婷  王 颖  柳 刚  张利达  韩 为
作者单位:1.安徽中医药大学第二附属医院,安徽 合肥 230061;2.广州医科大学附属脑科医院,广东 广州 510370
基金项目:国家自然科学基金项目(81973933);安徽省第十三批115产业创新团队项目(皖人才办〔2020〕4号);安徽省教育厅高校优秀拔尖人才培育计划(gxbjZD16)
摘    要:目的 观察通督调神针刺结合化瘀通络灸治疗痰瘀阻络型后循环缺血性眩晕(posterior circulation ischemic vertigo,PCIV)的临床疗效。方法 将60例PCIV患者随机分为对照组和治疗组,每组30例。两组患者均接受基础治疗,治疗组患者再接受通督调神针刺和化瘀通络灸治疗,对照组患者再口服盐酸氟桂利嗪胶囊。治疗前后分别观察两组患者眩晕障碍量表(dizziness handicap inventory,DHI)评分、痰瘀阻络证积分、静脉血内皮祖细胞(endothelial progenitor cells,EPCs)计数,比较两组临床疗效。结果 治疗组、对照组分别脱落3、2例患者。与治疗前比较,两组患者治疗后DHI评分、痰瘀阻络证积分均显著降低(P<0.05),EPCs计数显著升高(P<0.05),且治疗组DHI评分、痰瘀阻络证积分降低程度和EPCs计数升高程度均显著大于对照组(P<0.05)。治疗组临床疗效显著优于对照组(P<0.05)。结论 通督调神针刺结合化瘀通络灸治疗PCIV的临床疗效确切。

关 键 词:后循环缺血性眩晕  痰瘀阻络证  通督调神针刺  化瘀通络灸  内皮祖细胞

Clinical Effect of Tongdu Tiaoshen Acupuncture Combined with Huayu Tongluo Moxibustion in Treatment of Posterior Circulation Ischemic Vertigo with Syndrome of Phlegm Stasis Blocking Collaterals
Institution:1.The Second Affiliated Hospital of Anhui University of Chinese Medicine, Anhui Hefei 230061, China; 2.The Affiliated Brain Hospital of Guangzhou Medical University, Guangdong Guangzhou 510370, China
Abstract:Objective To investigate the clinical effect of Tongdu Tiaoshen acupuncture combined with Huayu Tongluo moxibustion in the treatment of posterior circulation ischemic vertigo (PCIV) with syndrome of phlegm stasis blocking collaterals.Methods A total of 60 patients with PCIV were randomly divided into control group and treatment group, with 30 patients in each group. In addition to basic treatment, the patients in the treatment group were given Tongdu Tiaoshen acupuncture combined with Huayu Tongluo moxibustion, and those in the control group were given oral administration of flunarizine hydrochloride capsules. The two groups were observed in terms of Dizziness Handicap Inventory (DHI) score, syndrome score of phlegm stasis blocking collaterals, and the number of venous endothelial progenitor cells (EPCs) before and after treatment, and treatment outcome was compared between the two groups.Results Three patients in the treatment group and two in the control group were lost to follow up. After treatment, both groups had significant reductions in DHI score and syndrome score of phlegm stasis blocking collaterals (P<0.05) and a significant increase in the number of EPCs (P<0.05), and the treatment group had significantly greater changes in these indices than the control group (P<0.05). The treatment group had a significantly better clinical outcome than the control group (P<0.05).Conclusion Tongdu Tiaoshen acupuncture combined with Huayu Tongluo moxibustion has a marked clinical effect in the treatment of PCIV.
Keywords:Posterior circulation ischemic vertigo  Phlegm stasis blocking collaterals  Tongdu Tiaoshen acupuncture  Huayu Tongluo moxibustion  Endothelial progenitor cell
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