| 中国鄂温克族人群15个STR基因座多态性研究 |
| |
| 作者姓名： | Huang YL Gu MB Wang J |
| |
| 作者单位： | 1. 黑龙江省公安厅刑事技术处遗传室,黑龙江,哈尔滨,150008
2. 内蒙古科技大学医学院,内蒙古,包头,014010 |
| |
| 摘 要： | 目的调查15个STR基因座在中国鄂温克族人群中的基因频率分布。方法应用PowerPlex16System复合扩增系统,对99名鄂温克族无关个的血样DNA进行多态性研究。结果在鄂温克族人群中15个STR基因座偶合率(Pm)在0.0205～0.1733之间,个体识别概率(DP)在0.8267～0.9795之间,杂合度在0.6061～0.9091之间,三联非父排除率(PE)在0.4038～0.7690之间,多态性信息总量(PIC)在0.5985～0.8734之间,15个STR基因座总TDP值为0.9999999999998,所有基因座经χ2检验符合Hard-Weinberg平衡。结论上述15个STR基因座在鄂温克族人群中等位基因分布较好,个体识别率高,适合法医个体识别和亲子鉴定。
|
| 关 键 词： | 法科学 鄂温克族 STR基因座 复合扩增 遗传多态性 |
| 文章编号： | 1004-5619(2004)03-0162-02 |
| 修稿时间： | 2003年10月28 |
A genetic study of 15 STR loci in Chinese E Wen-ke population |
| |
| Huang YL,Gu MB,Wang J.A genetic study of 15 STR loci in Chinese E Wen-ke population[J].Journal of Forensic Medicine,2004,20(3):162-163,166. |
| |
| Authors: | Huang Yu-li Gu Mming-bo Wang Jian |
| |
| Institution: | Criminal Science & Technology Institute of Hei-longjiang Province, Harbin 150008, China. |
| |
| Abstract: | Objective To investigate the genetic polymorphisms of15STRs loci in Chinese E Wen-ke population.Methods DNA samples from99unrelated individuals in Chinese E Wen-ke population were screened by Power Plex16System and ABI3100Genetic Analyzer.Results The genotype frequencies of these15STR loci meet the Hardy-Weinberg expectation.The Matching probability of15STRs loci were between0.0205-0.1733,discriminating power(DP)at0.8267-0.9795,heterozygosity(Ho)at0.6061-0.9091,power of exclusion(PE)at0.4038-0.7690,polymorphism information content(PIC)at0.5985-0.8734.The total DP of15STRs loci is0.9999999999998.Conclusion Our results showed that the15STRs loci of Power Plex16System are valuable STR loci genetic marker system having high DP and are useful in forensic case work in Chinese E Wen-ke population. |
| |
| Keywords: | forensic science E Wenke population STR loci multiplexing PCR genetic polymorphism |
| 本文献已被 CNKI 维普 万方数据 PubMed 等数据库收录！ |
|
